Výsledky vyhledávání - "Peter L. Walinsky"

Effect of NADPH oxidase inhibition on cardiopulmonary bypass-induced lung injury

Autor: David B. Pearse, Jay G. Shake, David J. Caparrelli, Peter L. Walinsky, Jay L. Zweier, Eric A. Peck, Laura E. Welsh, William A. Baumgartner, Jorge D. Salazar, Jeffrey M. Dodd-o, Roy C. Ziegelstein

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 287:H927-H936

Cardiopulmonary bypass (CPB) causes acute lung injury. Reactive oxygen species (ROS) from NADPH oxidase may contribute to this injury. To determine the role of NADPH oxidase, we pretreated pigs with structurally dissimilar NADPH oxidase inhibitors. L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4f871568ea4f39f4ca34e74a8590d3
https://doi.org/10.1152/ajpheart.01138.2003

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Left Atrial–Inferior Vena Cava Bypass Achieves Retroperfusion of the Porcine Spinal Cord: Morphologic and Preliminary Physiologic Studies

Autor: J.Mark Redmond, John R. Doty, Vincent L. Gott, William A. Baumgartner, Melissa Haggerty, J. Brawn, Jorge D. Salazar, Peter L. Walinsky

Publikováno v: Journal of Surgical Research. 108:157-164

Background. Spinal cord injury remains a devastating complication after procedures on the descending thoracic aorta. A new model for retrograde perfusion of the spinal cord during aortic cross-clamping was evaluated for its potential role in preventi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac14310ec83aee565a431c45d3f99b20
https://doi.org/10.1006/jsre.2002.6534

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Reoperative MIDCAB grafting: 3-year clinical experience

Autor: Jorge D. Salazar, James D. Fonger, Marc S. Sussman, Peter L. Walinsky, Neal W. Salomon, John R. Doty

Publikováno v: European Journal of Cardio-Thoracic Surgery. 13:641-649

Objective: Minimally invasive direct coronary artery bypass (MIDCAB) is performed under direct vision without sternotomy or cardiopulmonary bypass. The technique is used in reoperative patients through various incisions to revascularize one or two ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2705b344f8119fb80062bd378002cd2a
https://doi.org/10.1016/s1010-7940(98)00086-4

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Assessing the impact of cerebral injury after cardiac surgery: will determining the mechanism reduce this injury?

Autor: Michael V. Johnston, John R. Doty, Elaine E. Tseng, Mary E. Blue, Malcolm V. Brock, J.Mark Redmond, Jorge D. Salazar, Juan C. Troncoso, William A. Baumgartner, Maura A. Goldsborough, Peter L. Walinsky

Publikováno v: The Annals of Thoracic Surgery. 67:1871-1873

Background . Central nervous system dysfunction continues to produce significant morbidity and associated mortality in patients undergoing cardiac surgery. Using a closed-chest canine cardiopulmonary bypass model, dogs underwent 2 h of hypothermic ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c5eaf84c7c0db261856d19bd4a7160
https://doi.org/10.1016/s0003-4975(99)00445-2

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Effect of bronchial artery blood flow on cardiopulmonary bypass-induced lung injury

Autor: Stephen M. Cattaneo, Brian T. Bethea, William A. Baumgartner, Laura E. Welsh, Eric A. Peck, Jorge D. Salazar, David B. Pearse, Jay G. Shake, Jeffrey M. Dodd-o, David J. Caparrelli, Peter L. Walinsky

Publikováno v: American journal of physiology. Heart and circulatory physiology. 286(2)

Cardiovascular surgery requiring cardiopulmonary bypass (CPB) is frequently complicated by postoperative lung injury. Bronchial artery (BA) blood flow has been hypothesized to attenuate this injury. The purpose of the present study was to determine t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf985477ff88709f122dd1cf02f428dd
https://pubmed.ncbi.nlm.nih.gov/14563666

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Wall tension is a potent negative regulator of in vivo thrombomodulin expression

Autor: Antony Y. Kim, David A. Kass, Jeffrey J. Rade, Ce Bian, Clayton B. Deming, Peter L. Walinsky, Renu Virmani, Frank D. Kolodgie, Jason L. Sperry

Publikováno v: Circulation research. 92(1)

Thrombomodulin (TM), a key component of the anticoagulant protein C pathway, is a major contributor to vascular thromboresistance. We previously found that TM protein expression is dramatically reduced in autologous vein grafts during the first two w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21361aa109d4ce237d038c020f987e2f
https://pubmed.ncbi.nlm.nih.gov/12522115

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Early loss of thrombomodulin expression impairs vein graft thromboresistance: implications for vein graft failure

Autor: Jason L. Sperry, Jay G. Shake, Clayton B. Deming, R. Scott Stuart, Charles T. Esmon, Jeffrey J. Rade, Richard H. Sohn, Frank D. Kolodgie, Peter L. Walinsky, Gregory B. Ang, Renu Virmani, Antony Y. Kim, Ce Bian, Eric A. Peck

Publikováno v: Circulation research. 90(2)

Thrombosis is the major cause of early vein graft failure. Our aim was to determine whether alterations in the expression of the anticoagulant proteins, thrombomodulin (TM) and the endothelial cell protein C receptor (EPCR), impair endothelial thromb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302b5b138a416c8e17df8e124f2d6280
https://pubmed.ncbi.nlm.nih.gov/11834714

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Initial experience with MIDCAB grafting using the gastroepiploic artery

Autor: Neal W. Salomon, John R. Doty, James D. Fonger, Peter L. Walinsky, Jorge D. Salazar

Publikováno v: The Annals of thoracic surgery. 68(2)

Background . Minimally invasive direct coronary artery bypass grafting with the gastroepiploic artery can be used in primary operations and reoperations to revascularize the inferior or anterior surface of the heart. Methods . Patients who had sympto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699cb7a0c3b62f74f1c49507cae58929
https://pubmed.ncbi.nlm.nih.gov/10475408

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Loss of thrombomodulin expression impairs vein graft thromboresistance

Autor: Gregory B. Ang, Charles T. Esmon, Eric A. Peck, Jason L. Sperry, Peter L. Walinsky, Renu Virmani, Jeffrey J. Rade, Frank D. Kolodgie, Jay G. Shake, Clayton B. Deming, Kenneth L. Baughman, Ce Bian, Antony Y. Kim

Publikováno v: Journal of the American College of Cardiology. 39:451

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41969ae679d511a1dee21762a76ce1b5
https://doi.org/10.1016/s0735-1097(02)82027-7

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Early experience with minimally invasive direct coronary artery bypass grafting with the internal thoracic artery

Autor: Peter L. Walinsky, James D. Fonger, Jorge D. Salazar, Neal W. Salomon, John R. Doty

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. (5):873-880

Objective: Minimally invasive direct coronary artery bypass is performed under direct vision without sternotomy or cardiopulmonary bypass. The technique can be used in both primary and reoperative cases by employing the internal thoracic artery to pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52e0e3575411d4447acb5f6e8487fca

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