Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Peter L. Tsenovoy"'
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Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway
Autor: Rita Rezzani, Komal Sodhi, Robert C. Touchon, Ellen Thompson, Peter L. Tsenovoy, Joseph I. Shapiro, Nader G. Abraham, John R. Falck, Jian Cao
Publikováno v: Prostaglandins & Other Lipid Mediators. :76-86
Myocardial infarction (MI) is complicated by ventricular fibrosis and associated diastolic and systolic failure. Emerging studies implicate Wnt1 signaling in the formation of new blood vessels. Epoxyeicosatrienoic acids (EETs)-mediated up-regulation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c953633a1e9bba9da7ce72ec891f5cfd
https://doi.org/10.1016/j.prostaglandins.2015.01.002
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2
Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin Sensitivity and Glucose Tolerance
Autor: Luigi Fabrizio Rodella, Susumu Ikehara, Ming Li, Rita Rezzani, Dong Hyun Kim, Wilbert S. Aronow, Stephen J. Peterson, Nader G. Abraham, Peter L. Tsenovoy
Publikováno v: Diabetes. 57:1526-1535
OBJECTIVE—We hypothesized that the induction of heme oxygenase (HO)-1 and increased HO activity, which induces arterial antioxidative enzymes and vasoprotection in a mouse and a rat model of diabetes, would ameliorate insulin resistance, obesity, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d4dbe6d65323e5f597232193f2090b
https://doi.org/10.2337/db07-1764
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3
Heme Oxygenase-Mediated Increases in Adiponectin Decrease Fat Content and Inflammatory Cytokines Tumor Necrosis Factor-α and Interleukin-6 in Zucker Rats and Reduce Adipogenesis in Human Mesenchymal Stem Cells
Autor: Nitin Puri, Angela Burgess, Ming Li, Peter L. Tsenovoy, John A. McClung, Nader G. Abraham, Francesco Addabbo, Dong Hyun Kim
Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 325:833-840
Adiponectin, an abundant adipocyte-derived plasma protein that modulates vascular function in type 2 diabetes, has been shown to provide cytoprotection to both pancreatic and vascular systems in diabetes. Therefore, we examined whether up-regulation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fe1084c62ad78a118005ed5a492d0f
https://doi.org/10.1124/jpet.107.135285
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4
Heme oxygenase expression in diabetes and in renal diseases: Mechanisms of cytoprotection
Autor: Peter L. Tsenovoy, Alvin I. Goodman, Nader G. Abraham
Publikováno v: Drug Discovery Today: Disease Mechanisms. 4:41-46
Heme oxygenase (HO) has been shown to be critical for attenuating reactive oxygen species (ROS) through its ability to degrade heme and produce carbon monoxide (CO) and bilirubin. Excess free heme and proinflammatory growth factors are major contribu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::804984d24e02cf077a757dec543a5fc9
https://doi.org/10.1016/j.ddmec.2007.06.006
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5
Patients with infective endocarditis and increased cardiac troponin I levels have a higher incidence of in-hospital mortality and valve replacement than those with normal cardiac troponin I levels
Autor: Wilbert S. Aronow, Magdaline S. Kopacz, Julie Joseph, Peter L. Tsenovoy
Publikováno v: Cardiology. 112(3)
Objectives: To investigate the association of increased cardiac troponin I levels with in-hospital mortality and valve replacement in patients with infective endocarditis (IE). Methods: The 62 patients included 36 men and 26 women, with a mean age of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce26e7103fc6ed4b278a26c7112ea671
https://pubmed.ncbi.nlm.nih.gov/18667821
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