Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter L. D. Wildfong"'
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 78, Iss 5, Pp 485-489 (2022)
The title compound, C10H13BrN2O3S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide
Externí odkaz:
https://doaj.org/article/275c0a7004734184b07f0e20ec05403e
Crystal structure of tert-butyl 4-[4-(4-fluorophenyl)-2-methylbut-3-yn-2-yl]piperazine-1-carboxylate
Autor:
Ashwini Gumireddy, Kevin DeBoyace, Alexander Rupprecht, Mohit Gupta, Saloni Patel, Patrick T. Flaherty, Peter L. D. Wildfong
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 77, Iss 4, Pp 360-365 (2021)
The title sterically congested piperazine derivative, C20H27FN2O2, was prepared using a modified Bruylants approach. A search of the Cambridge Structural Database identified 51 compounds possessing an N-tert-butyl piperazine substructure. Of these on
Externí odkaz:
https://doaj.org/article/f6a62e9d6de648d9ac40a4ad19ea1acb
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1126 (2021)
Ribavirin is a water-soluble antiviral compound which, owing to its inability to cross the blood–brain barrier, has limited effectiveness in treating viruses affecting the central nervous system. Direct nose-to-brain delivery was investigated for r
Externí odkaz:
https://doaj.org/article/903caee581ea48fe9ff802ab68f01b1b
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 7, Pp o1336-o1337 (2008)
There are two independent molecules in the asymmetric unit of the title compound, C11H13N3O3. The interplanar angles for the two rings of the benzimidazole ring system is 2.21 (12)° in one molecule and 0.72 (12)° in the other. The nitro group is tw
Externí odkaz:
https://doaj.org/article/e71307cbdef34686b5fbcee1cb598c05
Publikováno v:
Molecular Pharmaceutics. 19:3959-3972
Specific noncovalent drug-polymer interactions were analytically identified using Raman and Fourier transform infrared spectroscopy for amorphous solid dispersions (ASD) formed between either chlorpropamide or tolbutamide and polyvinylpyrrolidone vin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a561199a0d321d37b72f073df0a3065
https://doi.org/10.1021/acs.molpharmaceut.2c00434
https://doi.org/10.1021/acs.molpharmaceut.2c00434
Publikováno v:
Molecular Pharmaceutics. 19:303-317
A molecular descriptor known as R3m (the R-GETAWAY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89deee9141cb24748719e8689fe1e8dd
https://doi.org/10.1021/acs.molpharmaceut.1c00783
https://doi.org/10.1021/acs.molpharmaceut.1c00783
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 39(1-2)
An analytical, non-destructive method using parallel-beam transmission powder X-ray diffractometry (PXRD) is presented for in situ whole compact detection and quantification of solid-state phase transformations in powder compacts. Accurate quantifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddc4c3ee11eb6c2809164b97e0c63e41
https://pubmed.ncbi.nlm.nih.gov/15869857
https://pubmed.ncbi.nlm.nih.gov/15869857