Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Peter L Santa Maria"'
Autor:
Viktoria Schiel, Ritwija Bhattacharya, Ankur Gupta, Kourosh Eftekharian, Anping Xia, Peter L Santa Maria
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract The activation of the NLRP3 inflammasome has been linked to several inflammatory and autoinflammatory diseases. Despite cases of potential hearing improvement in immune-mediated diseases, direct evidence of the efficacy of targeting this mec
Externí odkaz:
https://doaj.org/article/6e9ff430e2f042b784066914ecbaa7a4
Autor:
Anping Xia, Anthony Thai, Zhixin Cao, Xiaohua Chen, Jing Chen, Brian Bacacao, Laurent A. Bekale, Viktoria Schiel, Paul L. Bollyky, Peter L. Santa Maria
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Chronic suppurative otitis media (CSOM) is the most common cause of permanent hearing loss in children in the developing world. A large component of the permanent hearing loss is sensory in nature and our understanding of the mech
Externí odkaz:
https://doaj.org/article/958afb0cf6b0467980759237b07e4366
Autor:
Alexander M. Choi MD, Michael J. Brenner MD, Daniel Gorelik, Isaac D. Erbele MD, Matthew G. Crowson MD, PhD, Prajoy Kadkade MD, Masayoshi Takashima MD, Peter L. Santa Maria MBBS, PhD, Robert S. Hong MD, Austin S. Rose MD, MBA, Benjamin T. Ostrander MD, MSE, Cyrus C. Rabbani MD, Robert J. Morrison MD, Philip A. Weissbrod MD, Alan D. Tate MD, Joshua J. Kain MD, Ioan A. Lina MD, Scott R. Shaffer MD, Omar G. Ahmed MD
Publikováno v:
OTO Open, Vol 6 (2022)
Objective To evaluate new medical devices and drugs pertinent to otolaryngology–head and neck surgery that were approved by the Food and Drug Administration (FDA) in 2021. Data Sources Publicly available FDA device and drug approvals from ENT (ear,
Externí odkaz:
https://doaj.org/article/8a6f35df2ea44d299a76fd277b91a61f
Publikováno v:
Otolaryngology Case Reports, Vol 23, Iss , Pp 100404- (2022)
Cochlear implants (CIs) are common treatments for people with severe to profound bilateral hearing loss and are used throughout the world in patients of all ages. While CIs provide management for people with severe hearing problems to hear and unders
Externí odkaz:
https://doaj.org/article/58c0e5683d064d9abc0a18f03549c137
Autor:
Michael J. Brenner MD, Jared A. Shenson MD, Austin S. Rose MD, MBA, Tulio A. Valdez MD, MSc, Masayoshi Takashima MD, Omar G. Ahmed MD, Philip A. Weissbrod MD, Robert S. Hong MD, PhD, Hamid Djalilian MD, Jeffrey S. Wolf MD, Robert J. Morrison MD, Peter L. Santa Maria MBBS, PhD, Isaac D. Erbele MD
Publikováno v:
OTO Open, Vol 5 (2021)
Objectives To evaluate new drugs and devices relevant to otolaryngology–head and neck surgery that were approved by the US Food and Drug Administration (FDA) in 2020. Data Sources Publicly available device and therapeutic approvals from ENT (ear, n
Externí odkaz:
https://doaj.org/article/90267ef6f02d4d93a83c75aa4a0c7a8e
Autor:
Adam C. Kaufman, Brian S. Bacacao, Betul Berkay, Devesh Sharma, Anupam Mishra, George A. O'Toole, James E. Saunders, Anping Xia, Laurent A. Bekale, Peter L. Santa Maria
Publikováno v:
Otol Neurotol
HYPOTHESIS: Commercially available povidone-iodine solution can eliminate biofilms and persister cells rapidly in in vivo achievable concentrations without inducing ototoxicity. BACKGROUND: Chronic suppurative otitis media (CSOM) is a substantial glo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441d8b365e56d98bc4ce7915d255a51b
https://doi.org/10.1097/mao.0000000000003726
https://doi.org/10.1097/mao.0000000000003726
Autor:
Jennifer S. Lin, Laurent A. Bekale, Natalia Molchanova, Josefine Eilsø Nielsen, Megan Wright, Brian Bacacao, Gill Diamond, Håvard Jenssen, Peter L. Santa Maria, Annelise E. Barron
Publikováno v:
ACS Infectious Diseases. 8:1823-1830
Although persister cells are the root cause of resistance development and relapse of chronic infections, more attention has been focused on developing antimicrobial agents against resistant bacterial strains than on developing anti-persister agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f06059634a99cfd151d0ad86b3e3a8
https://doi.org/10.1021/acsinfecdis.2c00288
https://doi.org/10.1021/acsinfecdis.2c00288
Autor:
Zhixin Cao, Xiaohua Chen, Jing Chen, Anping Xia, Brian Bacacao, Jessica Tran, Devesh Sharma, Laurent A. Bekale, Peter L. Santa Maria
Publikováno v:
Nanoscale
Persister cells are responsible for relapses of infections common in cystic fibrosis and chronic suppurative otitis media (CSOM). Yet, there are no Food and Drug Administration (FDA) approved antibiotics to eradicate persister cells. Frustratingly, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42c24d3ef5040097ad675fd474a9ff4
https://doi.org/10.1039/d2nr01003h
https://doi.org/10.1039/d2nr01003h
Publikováno v:
Polymers. 14(24)
Muco-adhesive drug delivery systems continue to be one of the most studied for controlled pharmacokinetics and pharmacodynamics. Briefly, muco-adhesive polymers, can be described as bio-polymers that adhere to the mucosal (mucus) surface layer, for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dafa25435ed573278a43c436acc35d
https://pubmed.ncbi.nlm.nih.gov/36559825
https://pubmed.ncbi.nlm.nih.gov/36559825
Publikováno v:
Otolaryngology–Head and Neck Surgery. 167:341-349
To report health utilization patterns and outcomes of medical and surgical management in patients with chronic suppurative otitis media (CSOM).Retrospective cohort.Academic otology clinic.This study included 175 patients with CSOM with a first clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfb0dfb583255c6bbff47760be3eb61
https://doi.org/10.1177/01945998211050626
https://doi.org/10.1177/01945998211050626