Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Peter L E M van Lent"'
Autor:
Onno J Arntz, Bartijn C H Pieters, Peter L E M van Lent, Marije I Koenders, Peter M van der Kraan, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236508 (2020)
Extracellular vesicles (EVs) are cell membrane-derived phospholipid bilayer nanostructures that contain bioactive proteins, enzymes, lipids and polymers of nucleotides. They play a role in intercellular communication and are present in body fluids. E
Externí odkaz:
https://doaj.org/article/16f57ed371db47b689c9c415c50d4931
Autor:
Rebecca Rogier, Thomas H A Ederveen, Harm Wopereis, Anita Hartog, Jos Boekhorst, Sacha A F T van Hijum, Jan Knol, Johan Garssen, Birgitte Walgreen, Monique M Helsen, Peter M van der Kraan, Peter L E M van Lent, Fons A J van de Loo, Shahla Abdollahi-Roodsaz, Marije I Koenders
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0227517 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0219366.].
Externí odkaz:
https://doaj.org/article/e8f37efd65e74fe29b0a7b6a14b2ed58
Autor:
Rebecca Rogier, Thomas H A Ederveen, Harm Wopereis, Anita Hartog, Jos Boekhorst, Sacha A F T van Hijum, Jan Knol, Johan Garssen, Birgitte Walgreen, Monique M Helsen, Peter M van der Kraan, Peter L E M van Lent, Fons A J van de Loo, Shahla Abdollahi-Roodsaz, Marije I Koenders
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219366 (2019)
The intestinal microbiome is perturbed in patients with new-onset and chronic autoimmune inflammatory arthritis. Recent studies in mouse models suggest that development and progression of autoimmune arthritis is highly affected by the intestinal micr
Externí odkaz:
https://doaj.org/article/70f558271bb5407ab58ed64170a7d680
Autor:
Claire E J Waterborg, Marije I Koenders, Peter L E M van Lent, Peter M van der Kraan, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205902 (2018)
Rheumatoid arthritis is an auto-immune disease of the synovial joints, hallmarked by chronic inflammation and subsequent progressive tissue destruction. TYRO3, AXL and MER (gene name Mertk) (TAM) receptors are part of a negative feedback signaling sy
Externí odkaz:
https://doaj.org/article/e80541c2489a478b8885789171037e56
Autor:
Mathijs G A Broeren, Marieke de Vries, Miranda B Bennink, Peter L E M van Lent, Peter M van der Kraan, Marije I Koenders, Rogier M Thurlings, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167076 (2016)
Osteoarthritis (OA) is a degenerative joint disease affecting cartilage and is the most common form of arthritis worldwide. One third of OA patients have severe synovitis and less than 10% have no evidence of synovitis. Moreover, synovitis is predict
Externí odkaz:
https://doaj.org/article/bc6c8d22553b4ed388e67602cb7f9c54
Autor:
Bartijn C H Pieters, Onno J Arntz, Miranda B Bennink, Mathijs G A Broeren, Arjan P M van Caam, Marije I Koenders, Peter L E M van Lent, Wim B van den Berg, Marieke de Vries, Peter M van der Kraan, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121123 (2015)
ScopeExtracellular vesicles, including exosomes, have been identified in all biological fluids and rediscovered as an important part of the intercellular communication. Breast milk also contains extracellular vesicles and the proposed biological func
Externí odkaz:
https://doaj.org/article/f09e52a2843b43f2bebd39101869033a
Autor:
Eline A Vermeij, Marije I Koenders, Miranda B Bennink, Lindsey A Crowe, Lionel Maurizi, Jean-Paul Vallée, Heinrich Hofmann, Wim B van den Berg, Peter L E M van Lent, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126687 (2015)
Superparamagnetic Iron Oxide Nanoparticles (SPION) are used in diagnostic imaging of a variety of different diseases. For such in-vivo application, an additional coating with a polymer, for example polyvinyl alcohol (PVA), is needed to stabilize the
Externí odkaz:
https://doaj.org/article/65221a7ed41b49c39dfa59621959c74c
Autor:
Nathalie G. M. Thielen, Margot Neefjes, Elly L. Vitters, Henk M. van Beuningen, Arjen B. Blom, Marije I. Koenders, Peter L. E. M. van Lent, Fons A. J. van de Loo, Esmeralda N. Blaney Davidson, Arjan P. M. van Caam, Peter M. van der Kraan
Publikováno v:
Cells, Vol 11, Iss 7, p 1232 (2022)
During osteoarthritis (OA), hypertrophy-like chondrocytes contribute to the disease process. TGF-β’s signaling pathways can contribute to a hypertrophy(-like) phenotype in chondrocytes, especially at high doses of TGF-β. In this study, we examine
Externí odkaz:
https://doaj.org/article/a631d94a620f4eafa36cfb68ffd19d7e
Autor:
Onno J. Arntz, Bartijn C. H. Pieters, Rogier M. Thurlings, Mark H. Wenink, Peter L. E. M. van Lent, Marije I. Koenders, Frank H. J. van den Hoogen, Peter M. van der Kraan, Fons A. J. van de Loo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that mainly affects synovial joints. Validated laboratory parameters for RA diagnosis are higher blood levels of rheumatoid factor IgM (IgM-RF), anti-citrullinated protein autoantibodies
Externí odkaz:
https://doaj.org/article/f63d323f91014ff290801a9c8a3e777a
Autor:
Martijn H J van den Bosch, Thomas Vogl, Johannes Roth, Marije I. Koenders, Irene Di Ceglie, Peter L E M van Lent, Edwin J. W. Geven, Arjen B. Blom
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Arthritis Research & Therapy
Arthritis Research & Therapy, 23
Arthritis Research & Therapy, 23, 1
Arthritis Research & Therapy
Arthritis Research & Therapy, 23
Arthritis Research & Therapy, 23, 1
Background Excessive osteoclast activity, which is strongly stimulated by pro-inflammatory mediators, results in bone and cartilage degeneration as central features of many arthritides. Levels of the alarmin S100A8/A9 and interleukin (IL)-1β are bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e48952204a435b24a1f6386fba5caf
https://doaj.org/article/007fde91b5b342df9e647aa4c1e5e630
https://doaj.org/article/007fde91b5b342df9e647aa4c1e5e630