Sacral Spinal Cord Transection and Isolated Sacral Cord Preparation to Study Chronic Spinal Cord Injury in Adult Mice

Autor: Carmelo Bellardita, Maite Marcantoni, Peter Löw, Ole Kiehn

Publikováno v: Bio-Protocol, Vol 8, Iss 7 (2018)

Spinal cord injury (SCI) is characterized by multiple sensory/motor impairments that arise from different underlying neural mechanisms. Linking specific sensory/motor impairments to neural mechanism is limited by a lack of direct experimental access

Externí odkaz: https://doaj.org/article/e8573f05ab9e4033b4fdfb1b61c63666

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

On the (in)consistency of perturbation theory at finite temperature

Autor: Peter Lowdon, Owe Philipsen

Publikováno v: Journal of High Energy Physics, Vol 2024, Iss 8, Pp 1-22 (2024)

Abstract A well-known difficulty of perturbative approaches to quantum field theory at finite temperature is the necessity to address theoretical constraints that are not present in the vacuum theory. In this work, we use lattice simulations of scala

Externí odkaz: https://doaj.org/article/1bf20f4ccf60443eb060745f1a869d92

Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

Autor: Raghavendra Selvan, Ilary Allodi, Ole Kiehn, Roser Montañana-Rosell, Peter Löw

Publikováno v: Nature Communications
Allodi, I, Montañana-Rosell, R, Selvan, R, Löw, P & Kiehn, O 2021, ' Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons ', Nature Communications, vol. 12, no. 1, 3251 . https://doi.org/10.1038/s41467-021-23224-7
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

ALS is characterized by progressive inability to execute movements. Motor neurons innervating fast-twitch muscle-fibers preferentially degenerate. The reason for this differential vulnerability and its consequences on motor output is not known. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccdc89c04a0317bdef7c2aaf98a8855
http://europepmc.org/articles/PMC8166981

Early delivery and prolonged treatment with nimodipine prevents the development of spasticity after spinal cord injury in mice

Autor: Dusan Bartsch, Peter Löw, Ole Kiehn, Maite Marcantoni, Andrea Fuchs, Carmelo Bellardita

Publikováno v: Science Translational Medicine. 12

Spasticity, one of the most frequent comorbidities of spinal cord injury (SCI), disrupts motor recovery and quality of life. Despite major progress in neurorehabilitative and pharmacological approaches, therapeutic strategies for treating spasticity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7e6174966e63cec2bb94a28768bda5
https://doi.org/10.1126/scitranslmed.aay0167