Zobrazeno 1 - 10
of 323
pro vyhledávání: '"Peter Lönnecke"'
Autor:
Lydia Kuhnert, Robert Kuhnert, Menyhárt B. Sárosi, Cathleen Lakoma, Birte K. Scholz, Peter Lönnecke, Evamarie Hey‐Hawkins, Walther Honscha
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 280-290 (2024)
Success of chemotherapy is often hampered by multidrug resistance. One mechanism for drug resistance is the elimination of anticancer drugs through drug transporters, such as breast cancer resistance protein (BCRP; also known as ABCG2), and causes a
Externí odkaz:
https://doaj.org/article/e96a44f6f69c429da99bfd278b0a0705
Autor:
Kyzgaldak Ramazanova, Anna Karina Müller, Peter Lönnecke, Oldamur Hollóczki, Barbara Kirchner, Evamarie Hey-Hawkins
Publikováno v:
Molecules, Vol 28, Iss 20, p 7163 (2023)
The reactive P-N bond in 1-phospha-2-azanorbornenes is readily cleaved by simple alcohols to afford P-chiral 2,3-dihydrophosphole derivatives as a racemic mixture. The isolation of the products was not possible due to the reversibility of the reactio
Externí odkaz:
https://doaj.org/article/a831b413631e478ba1556cca250dd6d4
Autor:
Kyzgaldak Ramazanova, Soumyadeep Chakrabortty, Fabian Kallmeier, Nadja Kretzschmar, Sergey Tin, Peter Lönnecke, Johannes G. de Vries, Evamarie Hey-Hawkins
Publikováno v:
Molecules, Vol 28, Iss 17, p 6210 (2023)
Sulfur-protected enantiopure P-chiral 1-phosphanorbornane silyl ethers 5a,b are obtained in high yields via the reaction of the hydroxy group of P-chiral 1-phosphanorbornane alcohol 4 with tert-butyldimethylsilyl chloride (TBDMSCl) and triphenylsilyl
Externí odkaz:
https://doaj.org/article/f636491c077c4c2ab4054dfd93a6fb20
Autor:
Aleksandr Kazimir, Benedikt Schwarze, Peter Lönnecke, Sanja Jelača, Sanja Mijatović, Danijela Maksimović-Ivanić, Evamarie Hey-Hawkins
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1769 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/ae97df690827404188397063486b55c6
Autor:
Sebastian Braun, Sanja Jelača, Markus Laube, Sven George, Bettina Hofmann, Peter Lönnecke, Dieter Steinhilber, Jens Pietzsch, Sanja Mijatović, Danijela Maksimović-Ivanić, Evamarie Hey-Hawkins
Publikováno v:
Molecules, Vol 28, Iss 11, p 4547 (2023)
Targeting inflammatory mediators and related signaling pathways may offer a rational strategy for the treatment of cancer. The incorporation of metabolically stable, sterically demanding, and hydrophobic carboranes in dual cycloxygenase-2 (COX-2)/5-l
Externí odkaz:
https://doaj.org/article/4f70741954bc43e89ae933ec951f77bd
Autor:
Ivana Predarska, Mohamad Saoud, Ibrahim Morgan, Peter Lönnecke, Goran N. Kaluđerović, Evamarie Hey-Hawkins
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 595 (2023)
Organotin(IV) carboxylates are a class of compounds explored as alternatives to platinum-containing chemotherapeutics due to propitious in vitro and in vivo results, and distinct mechanisms of action. In this study, triphenyltin(IV) derivatives of no
Externí odkaz:
https://doaj.org/article/9e6474c0a2c64cefbe21977ed436cfe8
Autor:
Zeno B. G. Fickenscher, Peter Lönnecke, Anna K. Müller, Oldamur Hollóczki, Barbara Kirchner, Evamarie Hey-Hawkins
Publikováno v:
Molecules, Vol 28, Iss 6, p 2574 (2023)
Two heterobimetallic Mo,M’ complexes (M’ = IrIII, RhIII) were synthesized and fully characterized. Their catalytic activity in homogeneous carbon dioxide hydrogenation to formate was studied. A pronounced synergistic effect between the two metals
Externí odkaz:
https://doaj.org/article/0e2346ea2abc448b89cd661948e14afb
Autor:
Aleksandr Kazimir, Benedikt Schwarze, Peter Lönnecke, Sanja Jelača, Sanja Mijatović, Danijela Maksimović-Ivanić, Evamarie Hey-Hawkins
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 682 (2023)
The luminal A-subtype of breast cancer, where the oestrogen receptor α (ERα) is overexpressed, is the most frequent one. The prodrug tamoxifen (1) is the clinically used agent, inhibiting the ERα activity via the formation of several active metabo
Externí odkaz:
https://doaj.org/article/f3ca02a462c746968109a80d7bc93e0c
Autor:
Antonio Buzharevski, Svetlana Paskas, Markus Laube, Peter Lönnecke, Wilma Neumann, Blagoje Murganic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Jens Pietzsch, Evamarie Hey-Hawkins
Publikováno v:
ACS Omega, Vol 4, Iss 5, Pp 8824-8833 (2019)
Externí odkaz:
https://doaj.org/article/e85dd4b4cc654f5fa2d028f50f44e932
Autor:
Martin Kellert, Jan-Simon Jeshua Friedrichs, Nadine Anke Ullrich, Alexander Feinhals, Jonas Tepper, Peter Lönnecke, Evamarie Hey-Hawkins
Publikováno v:
Molecules, Vol 26, Iss 7, p 2057 (2021)
The development of novel, tumor-selective and boron-rich compounds as potential agents for use in boron neutron capture therapy (BNCT) represents a very important field in cancer treatment by radiation therapy. Here, we report the design and synthesi
Externí odkaz:
https://doaj.org/article/e6a23bb2b2874a639d2eb7978073ddf6