Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Peter Kulmburg"'
Autor:
Beata Mezes, Peter Kulmburg, Roland Mertelsmann, Albrecht Lindemann, Andreas Mackensen, Lei Cao, Hendrik Veelken, Felicia M. Rosenthal
Publikováno v:
Scopus-Elsevier
New strategies based on gene transfer technology are employed in cancer therapy. Cytokines are polypeptides involved in immunity and inflammation, and essentially control the magnitude of the immune response. Genetically modified tumor cells releasin
Autor:
Gabriele Köhler, I. Hentrich, Dirk Behringer, Michael Lahn, Albrecht Lindemann, David N. Iklé, Regina Kunzmann, Peter Kulmburg, Paul Fisch, Hendrik Veelken, Birgit Muschal, Heike Jesuiter
Publikováno v:
European Urology. 35:70-80
The objectives of this study were to assess cytokine secretion in human renal cell carcinoma (RCC) and to identify cytokines contributing to the immunomodulatory effect of tumor cells.Cytokine secretion in the supernatant of primary tumor cell cultur
Autor:
Peter Kulmburg, Andreas Mackensen, C. Schmoor, Albrecht Lindemann, Hendrik Veelken, R H Mertelsmann, F. M. Rosenthal
Publikováno v:
Journal of Molecular Medicine. 75:223-229
We evaluated the survival, transgene production, and copy numbers of integrated plasmid units per host genome after lipofection with mono- and bicistronic plasmid vectors in different cell lines and under various conditions. The addition of an integr
Autor:
Felicia M. Rosenthal, Andreas Mackensen, Albrecht Lindemann, J. Hasse, Gabriele Köhler, B Franke, W Schultze-Seemann, Hendrik Veelken, U Brennscheidt, D Becker, Peter Kulmburg, M Lahn, H Keller, E.H. Farthmann, Roland Mertelsmann
Publikováno v:
International Journal of Cancer. 70:269-277
Tumor cells transfected to express immunostimulatory cytokines, or admixed with similarly modified bystander cells, are able to induce immune responses against unmodified tumor cells in animal models. For treatment of human patients, a vaccine compos
Autor:
Roland Mertelsmann, Albrecht Lindemann, Gabriele Köhler, Reinhard Früh, Peter Kulmburg, Andreas Mackensen, Carolin Pfeifer, Hendrik Veelken, Felicia M. Rosenthal
Publikováno v:
Scopus-Elsevier
Although long-term expression of therapeutic molecules is necessary for the treatment of permanent deficiencies, short-term expression of therapeutic molecules inducing local or systemic effects is preferable in clinical situations where temporary su
Autor:
Hans-Eckart Schaefer, Albrecht Lindemann, Andreas Mackensen, Hendrik Veelken, Birgit Herbst, Gabriele Köhler, Felicia M. Rosenthal, Roland Mertelsmann, Peter Kulmburg, Paul Fisch
Publikováno v:
Blood. 88:2541-2548
We have demonstrated recently that Birbeck granule-positive Langerhans cells (LC) can be derived from CD34+ peripheral blood progenitor cells in the presence of a seven-cytokine cocktail (CC7–7). Here, we show that the sequential use of early-actin
Autor:
Guang Y. Wang, Peter Kulmburg, Alexander D. Bach, Ulrich Kneser, Stefan Schultze-Mosgau, Raymund E. Horch, Jing N. Huan, Harun Seyhan, Mark D. Jeschke, Sheng D. Ge, Steven Dooley, Jürgen Kopp, Kang Ying
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 10(1)
Epidermal regeneration is a complex process, strongly influenced by growth factors, including keratinocyte growth factor (KGF). The objective of this study was to establish immortalized HaCaT keratinocytes and KMST-6-fibroblasts stably expressing KGF
Autor:
Jean J.M.C.H. delaRosette, Filippo Di Loro, J.D. VanGool, W.L. Strohmaier, J. VandeWalle, Michael Marberger, K.H. Bichler, Martin Schostak, P. Hoebeke, Ingrid C. Wettig, A. Páez, Andrea Amorosi, Albrecht Lindemann, M. Luján, Laura Ishak, Takashi Morita, Gabriele Köhler, K. Everaert, Rüdiger Heicappell, Francesco Pagano, Harrie P. Beerlage, Thomas Sauter, Vito Pansadoro, Herbert Leyh, E. VanLaecke, Pierfrancesco Bassi, Dirk Behringer, David N. Iklé, Kurt Miller, FransM.J. Debruyne, Hessel Wijkstra, Michael Lahn, Peter Kulmburg, Regina Kunzmann, Vincent Ravery, Rene G. Aarnink, A. Herrero, Cora N. Sternberg, Paul Fisch, Markus Müller, Tomonori Yamanishi, Kazuki Kawabe, Andrea Fanfani, Yukio Homma, I. Hentrich, Ursula Steiner, Birgit Muschal, Jeremy Crew, C.A. Hajivassiliou, E. Sánchez, Uwe Treiber, A. Berenguer, E. Martín, Roberto Ponchietti, Kosaku Yasuda, Hendrik Veelken, Pierre Conort, T. Keller, Laurent Boccon-Gibod, Heike Jesuiter
Publikováno v:
European urology. 35(1)
Autor:
Hendrik Veelken, Albrecht Lindemann, B Leutgeb, H.H. Fiebig, Peter Kulmburg, Andreas Mackensen
Publikováno v:
Scopus-Elsevier
Success of gene replacement therapy depends on long-term, high level expression of the transgene. Gene therapy vectors incorporating a promoter of a constitutively active eukaryotic gene may allow long-term expression in vivo, but the expression leve
Autor:
T. Dodic, Cao L, C. Andree, X. Y. Jiao, Peter Kulmburg, E. Tanczos, B. Flis, G. B. Stark, J. Kopp
Publikováno v:
Biological Matrices and Tissue Reconstruction ISBN: 9783642643477
Gene transfer offers an attractive method for the localized and persistent active delivery of growth factors to healing wounds: Gene therapy allows the controlled modification of cells to secrete the continuous localized production of polypeptides in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b74784d47c6b4528ef1e765f34b3323e
https://doi.org/10.1007/978-3-642-60309-9_6
https://doi.org/10.1007/978-3-642-60309-9_6