Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Peter Kuckenberg"'
Autor:
Caroline Kubaczka, Claire Senner, Marcos J. Araúzo-Bravo, Neha Sharma, Peter Kuckenberg, Astrid Becker, Andreas Zimmer, Oliver Brüstle, Michael Peitz, Myriam Hemberger, Hubert Schorle
Publikováno v:
Stem Cell Reports, Vol 2, Iss 2, Pp 232-242 (2014)
Trophoblast stem cells (TSCs) are in vitro equivalents to the precursor cells of the placenta. TSCs are cultured in serum-rich medium with fibroblast growth factor 4, heparin, and embryonic-fibroblast-conditioned medium. Here, we developed a simple m
Externí odkaz:
https://doaj.org/article/bf3b7ad7543542b0b80dc969a20137d6
Autor:
Daniel Holl, Peter Kuckenberg, Tatiana Woynecki, Angela Egert, Astrid Becker, Sebastian Huss, Dirk Stabenow, Andreas Zimmer, Percy Knolle, René Tolba, Hans-Peter Fischer, Hubert Schorle
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22034 (2011)
BackgroundThe transcription factor Tcfap2c has been demonstrated to be essential for various processes during mammalian development. It has been found to be upregulated in various undifferentiated tumors and is implicated with poor prognosis. Tcfap2c
Externí odkaz:
https://doaj.org/article/173b8efce5f548cc942fd9a96206ad71
Autor:
Elke Winterhager, Betina van Fürden, Friederike Seiffe, Alexey Tomilin, Sandra Buhl, Tatiana Woynecki, E. N. Tolkunova, Hubert Schorle, Markus Moser, Peter Kuckenberg
Publikováno v:
Molecular and Cellular Biology. 30:3310-3320
In mammals, cell lineage specification is established at the blastocyst stage. At this stage, transcription factor Cdx2 represses pluripotency genes, thus promoting extraembryonic trophoblast fate. Recently, transcription factor Gata3 was shown to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64216b0067f6cbdf5adcdf2d660f76a8
https://doi.org/10.1128/mcb.01215-09
https://doi.org/10.1128/mcb.01215-09
Autor:
Dawid Eckert, Daniel Nettersheim, Katharina Biermann, Hubert Schorle, Ad J. M. Gillis, Leendert H. J. Looijenga, Susanne Weber, Sabine Schäfer, Julia Ehlermann, Peter Kuckenberg, Uwe Werling
Publikováno v:
Biology of Reproduction. 82:214-223
Formation of the germ cell lineage involves multiple processes, including repression of somatic differentiation and reacquisition of pluripotency as well as a unique epigenetic constitution. The transcriptional regulator Prdm1 has been identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda084b429cbf2f00e3086a7de6d6211
https://doi.org/10.1095/biolreprod.109.078717
https://doi.org/10.1095/biolreprod.109.078717
Autor:
Elisabeth Kühnel, Yvonne Koch, Elke Winterhager, Neha Sharma, Hubert Schorle, Stephanie Kaiser, Alexandra Gellhaus, Peter Kuckenberg
Publikováno v:
Biology of Reproduction. 93
Tfap2c is required for placental development and trophoblast stem cell maintenance. Deletion of Tfap2c results in early embryonic loss because of failure in placental development. We evaluated the effect of reduced Tfap2c expression on fetal outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::087e9a889ee75576264446a27aef230d
https://doi.org/10.1095/biolreprod.114.126474
https://doi.org/10.1095/biolreprod.114.126474
Autor:
Stephanie, Kaiser, Yvonne, Koch, Elisabeth, Kühnel, Neha, Sharma, Alexandra, Gellhaus, Peter, Kuckenberg, Hubert, Schorle, Elke, Winterhager
Publikováno v:
Biology of reproduction. 93(2)
Tfap2c is required for placental development and trophoblast stem cell maintenance. Deletion of Tfap2c results in early embryonic loss because of failure in placental development. We evaluated the effect of reduced Tfap2c expression on fetal outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfa7e942bb12a4447f8b769eb943475e
https://pubmed.ncbi.nlm.nih.gov/26063869
https://pubmed.ncbi.nlm.nih.gov/26063869
Publikováno v:
Reproductive biomedicine online. 25(1)
In recent years, knowledge regarding the genetic and epigenetic programmes governing specification, maintenance and differentiation of the extraembryonic lineage has advanced substantially. Establishment and analysis of mice deficient in genes implic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407acc5c5e1d6a2b4b0e3579620f5b25
https://pubmed.ncbi.nlm.nih.gov/22560121
https://pubmed.ncbi.nlm.nih.gov/22560121
Autor:
Hubert Schorle, Percy A. Knolle, Sebastian Huss, Angela Egert, Peter Kuckenberg, D Stabenow, Astrid Becker, Hans-Peter Fischer, Daniel Holl, Tatiana Woynecki, Andreas Zimmer, Rene Tolba
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e22034 (2011)
PLOS ONE 6(7), e22034 (2011). doi:10.1371/journal.pone.0022034
PLoS ONE, Vol 6, Iss 7, p e22034 (2011)
PLOS ONE 6(7), e22034 (2011). doi:10.1371/journal.pone.0022034
PLoS one 6(7), e22034 (2011). doi:10.1371/journal.pone.0022034
Published by PLoS [u.a.], Lawrence, Kan.
Published by PLoS [u.a.], Lawrence, Kan.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f54f91127f514df2b54b6c5ffa1b40
https://pubmed.ncbi.nlm.nih.gov/21779369
https://pubmed.ncbi.nlm.nih.gov/21779369
Autor:
Oliver Brüstle, Caroline Kubaczka, Michael Peitz, Astrid Becker, Angela Egert, Andreas Zimmer, Eva Wardelmann, Hubert Schorle, Peter Kuckenberg
Publikováno v:
Molecular and cellular biology. 31(8)
In mammals, the first cell fate decision is initialized by cell polarization at the 8- to 16-cell stage of the preimplantation embryo. At this stage, outside cells adopt a trophectoderm (TE) fate, whereas the inside cell population gives rise to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65262891dac4c92e3f7138c984827bcd
https://pubmed.ncbi.nlm.nih.gov/21300784
https://pubmed.ncbi.nlm.nih.gov/21300784
Autor:
Susanne, Weber, Dawid, Eckert, Daniel, Nettersheim, Ad J M, Gillis, Sabine, Schäfer, Peter, Kuckenberg, Julia, Ehlermann, Uwe, Werling, Katharina, Biermann, Leendert H J, Looijenga, Hubert, Schorle
Publikováno v:
Biology of reproduction. 82(1)
Formation of the germ cell lineage involves multiple processes, including repression of somatic differentiation and reacquisition of pluripotency as well as a unique epigenetic constitution. The transcriptional regulator Prdm1 has been identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::144b64a50ecda01c6bea4113f1fcd705
https://pubmed.ncbi.nlm.nih.gov/19776388
https://pubmed.ncbi.nlm.nih.gov/19776388