Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Peter Kletting"'
Autor:
Catherine Meyer, Vikas Prasad, Andreea Stuparu, Peter Kletting, Gerhard Glatting, Jonathan Miksch, Christoph Solbach, Katharina Lueckerath, Lea Nyiranshuti, Shaojun Zhu, Johannes Czernin, Ambros J. Beer, Roger Slavik, Jeremie Calais, Magnus Dahlbom
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Background PSMA-TO-1 (“Tumor-Optimized-1”) is a novel PSMA ligand with longer circulation time than PSMA-617. We compared the biodistribution in subcutaneous tumor-bearing mice of PSMA-TO-1, PSMA-617 and PSMA-11 when labeled with 68Ga an
Externí odkaz:
https://doaj.org/article/f0b657a7735b4a30a9347b512a4f3d6a
Autor:
Deni Hardiansyah, Ade Riana, Peter Kletting, Nouran R. R. Zaid, Matthias Eiber, Supriyanto A. Pawiro, Ambros J. Beer, Gerhard Glatting
Publikováno v:
EJNMMI Physics, Vol 8, Iss 1, Pp 1-13 (2021)
Abstract Background The calculation of time-integrated activities (TIAs) for tumours and organs is required for dosimetry in molecular radiotherapy. The accuracy of the calculated TIAs is highly dependent on the chosen fit function. Selection of an a
Externí odkaz:
https://doaj.org/article/74dfce0f17c6427eb96b50034c91076e
Publikováno v:
EJNMMI Physics, Vol 7, Iss 1, Pp 1-14 (2020)
Abstract Background Individualized dosimetry is recommended for [177Lu]Lu-PSMA radioligand therapy (RLT) which is resource-intensive and protocols are often not optimized. Therefore, a simulation study was performed focusing on the determination of e
Externí odkaz:
https://doaj.org/article/9b0d79fee9c0425fb10d389915a913a3
Autor:
Elham Yousefzadeh-Nowshahr, Gordon Winter, Peter Bohn, Katharina Kneer, Christine A F von Arnim, Markus Otto, Christoph Solbach, Sarah Anderl-Straub, Dörte Polivka, Patrick Fissler, Joachim Strobel, Peter Kletting, Matthias W Riepe, Makoto Higuchi, Gerhard Glatting, Albert Ludolph, Ambros J Beer, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266906 (2022)
PurposeThe recent developments of tau-positron emission tomography (tau-PET) enable in vivo assessment of neuropathological tau aggregates. Among the tau-specific tracers, the application of 11C-pyridinyl-butadienyl-benzothiazole 3 (11C-PBB3) in PET
Externí odkaz:
https://doaj.org/article/5e8b71795e9c4e0099d9d89336fde267
Autor:
Nouran R. R. Zaid, Peter Kletting, Gordon Winter, Vikas Prasad, Ambros J. Beer, Gerhard Glatting
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2132 (2021)
In vivo alpha particle generators have great potential for the treatment of neuroendocrine tumors in alpha-emitter-based peptide receptor radionuclide therapy (α-PRRT). Quantitative pharmacokinetic analyses of the in vivo alpha particle generator an
Externí odkaz:
https://doaj.org/article/9fe4ba5e4e5b40dcb1620c823a7df539
Autor:
Peter Kletting, Christiane Schuchardt, Harshad R Kulkarni, Mostafa Shahinfar, Aviral Singh, Gerhard Glatting, Richard P Baum, Ambros J Beer
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162303 (2016)
In molecular radiotherapy with 177Lu-labeled prostate specific membrane antigen (PSMA) peptides, kidney and/or salivary glands doses limit the activity which can be administered. The aim of this work was to investigate the effect of the ligand amount
Externí odkaz:
https://doaj.org/article/84cf762f2a6e41a3bd5c9d80d2f21c84
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127934 (2015)
Radioimmunotherapy (RIT) with 90Y-labeled anti-CD66 antibody is used to selectively irradiate the red marrow (RM) before blood stem cell transplantation of acute leukemia patients. To calculate the activity to administer, time-integrated activity coe
Externí odkaz:
https://doaj.org/article/976796eff93b4754b6c2a42227773241
A Whole-Body Physiologically Based Pharmacokinetic Model for Alpha Particle Emitting Bismuth in Rats
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 37:41-46
Introduction/Aim: α particle emitting bismuth (212Bi) as decay product of 212Pb-labeled pharmaceuticals has been effective in targeted α particle therapy (TAT). Estimating the contribution of 212Bi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7ab21fa97154987b707ed9ded02137
https://doi.org/10.1089/cbr.2021.0028
https://doi.org/10.1089/cbr.2021.0028
Autor:
Christoph Solbach, Albert C. Ludolph, Patrick Fissler, Christine A. F. von Arnim, Peter Kletting, Katharina Kneer, Gordon Winter, Gerhard Glatting, Ambros J. Beer, Markus Otto, Sarah Anderl-Straub, Elham Yousefzadeh-Nowshahr, D. Polivka, Matthias W. Riepe, Vikas Prasad, Makoto Higuchi, Peter Bohn
Publikováno v:
Zeitschrift für medizinische Physik 31(1), 37-47 (2021). doi:10.1016/j.zemedi.2020.12.002
Quantification of tau load using 11C-PBB3-PET has the potential to improve diagnosis of neurodegenerative diseases. Although MRI-based pre-processing is used as a reference method, not all patients have MRI. The feasibility of a PET-based pre-process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b40ad3c19271fb613942cdef7f0f459
https://doi.org/10.1016/j.zemedi.2020.12.002
https://doi.org/10.1016/j.zemedi.2020.12.002
Publikováno v:
Nuklearmedizin - NuclearMedicine. 60:33-37
Aim The aim of this work was to systematically investigate the influence of the radionuclide half-life and affinity of prostate-specific membrane antigen (PSMA)-targeting ligands on the activity concentration for PET/CT imaging. Methods A whole-body
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755ad6e15c7432cb038cd479c7b9e5fa
https://doi.org/10.1055/a-1253-1535
https://doi.org/10.1055/a-1253-1535