Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Peter Kjellén"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:473-482
Collagen induced arthritis (CIA) is a common mouse model for rheumatoid arthritis. Two sets of truncated peptides derived from type II collagen have been prepared and tested for binding to A(q), a MHC-II molecule associated with development of CIA. B
Autor:
Marta E. Alarcón-Riquelme, Roland Jonsson, Åsa Johansson, Martin Sundler, Rikard Holmdahl, Andrew D. Cook, Peter Kjellén, Britt Nakken, Anne Isine Bolstad, Anna-Karin B. Lindqvist, Martina Johannesson
Publikováno v:
European Journal of Immunology. 31:1847-1856
The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjogren′s syndrome. To investigate whether NOD genes also promote autoimmune-mediatedarthritis we established a NOD strain with an MHC class
Publikováno v:
Journal of Autoimmunity. 11:213-221
T cell recognition of type II collagen (CII) is a crucial event in the induction of collagen-induced arthritis in the mouse. Several CII peptides have been shown to be of importance, dependent on which MHC haplotype the mouse carries. By sequencing t
Publikováno v:
International Immunology. 10:333-340
A protracted and relapsing form of experimental allergic encephalomyelitis (EAE) develops in the DA rat after immunization with rat spinal cord homogenate (SCH) emulsified in incomplete Freund's adjuvant (IFA). The genetic influence on this model has
Autor:
Ianeric Ivarsson, Rikard Holmdahl, Ulrica Brunsberg, Mikael Vestberg, Johan Broddefalk, Arne Svejgaard, Lars Fugger, Åke Engström, Bjarke E. Hansen, Peter Kjellén, Jan Kihlberg
Publikováno v:
European Journal of Immunology. 28:755-766
The Aq major histocompatibility complex (MHC) class II molecule is associated with susceptibility to murine collagen-induced arthritis (CIA), whereas the closely related H-2Ap molecule is not. To understand the molecular basis for this difference, we
Autor:
Martin Sundler, Anna-Karin B. Lindqvist, Kathrine Skarstein, Britt Nakken, Roland Jonsson, Peter Kjellén, Rikard Holmdahl
Publikováno v:
Scandinavian Journal of Immunology; 61(2), pp 119-127 (2005)
We investigated the role of the major histocompatibility complex (MHC) region in the specificity of autoimmunity by analysing specifically the development of sialadenitis, but also insulitis, nephritis and autoantibody production in autoimmune-prone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9540d93e17e14ce2d6dac3eda210ee
https://lup.lub.lu.se/record/133971
https://lup.lub.lu.se/record/133971
Autor:
Erik Wallström, Tomas Olsson, Peter Kjellén, Rikard Holmdahl, Johan Jirholt, Hans Lassmann, Khairul-Bariah Abdul-Majid, Robert A. Harris, Andreas Stefferl, Christine Stadelmann
Publikováno v:
Journal of neuroimmunology. 111(1-2)
We identified H-2(q) as a susceptible genotype for MOG-induced EAE by systematic screening of a series of H-2 congenic B10 mouse strains. A series of H-2(q)-bearing strains with divergent gene backgrounds were subsequently investigated. DBA/1 mice we
Publikováno v:
International immunology. 11(12)
The impact of the strength and promiscuity of the self peptide-MHC class II interaction on susceptibility to autoimmune disease is uncertain. Here we studied allelic differences in the affinity of rat MHC class II molecules for myelin basic protein (
Publikováno v:
Journal of Neuroimmunology
Autor:
Ülo Langel, Tiit Land, Kalev Kask, Anders Juréus, Juha Halonen, Külliki Saar, Peter Kjellén, Homa Hasanvan, Margus Pooga, Khadijeh Rezaei, Sandor Solyom, Uno Mäeorg, Tamas Bartfai, Asko Uri
Publikováno v:
Karolinska Institutet
ResearcherID
Europe PubMed Central
ResearcherID
Europe PubMed Central
Galanin is a neuroendocrine peptide which is 29/30 amino acids in length and is recognised by G-protein-coupled central nervous system receptors via its N-terminus. We synthesised several galanin receptor ligands and fragments around C-terminal exten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492c5e1b78883df104fe84befa53e051
http://www.ncbi.nlm.nih.gov/pubmed/9495593
http://www.ncbi.nlm.nih.gov/pubmed/9495593