Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Peter Kharchenko"'
Autor:
Harrison Specht, Edward Emmott, Aleksandra A. Petelski, R. Gray Huffman, David H. Perlman, Marco Serra, Peter Kharchenko, Antonius Koller, Nikolai Slavov
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background Macrophages are innate immune cells with diverse functional and molecular phenotypes. This diversity is largely unexplored at the level of single-cell proteomes because of the limitations of quantitative single-cell protein analys
Externí odkaz:
https://doaj.org/article/48c645d97c414b82abdbbbe683278eab
Autor:
Guo-Cheng Yuan, Long Cai, Michael Elowitz, Tariq Enver, Guoping Fan, Guoji Guo, Rafael Irizarry, Peter Kharchenko, Junhyong Kim, Stuart Orkin, John Quackenbush, Assieh Saadatpour, Timm Schroeder, Ramesh Shivdasani, Itay Tirosh
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Single-cell analysis is a rapidly evolving approach to characterize genome-scale molecular information at the individual cell level. Development of single-cell technologies and computational methods has enabled systematic investigation of ce
Externí odkaz:
https://doaj.org/article/52a3f62434394e26b80ed3c3002e85e6
Abstract 2456: Transcriptional signatures of stem cell phenotypes in normal and clonal hematopoiesis
Publikováno v:
Cancer Research. 83:2456-2456
Clonal hematopoiesis (CH) is an age-related clonal expansion of hematopoietic stem cells (HSCs). Factors that shape the progression of CH are only beginning to be characterized. HSCs are a heterogeneous population of cells with distinct clonal output
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bebbb7fd32a63854772e2604b58f4b2
https://doi.org/10.1158/1538-7445.am2023-2456
https://doi.org/10.1158/1538-7445.am2023-2456
Autor:
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte Verhoeven, Alexander Subtelny, Dimitar Zlatev, Matthew Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Macosko, Chin-Lee Wu, David Scadden, Douglas Dahl, Ninib Baryawno, Philip Saylor, Peter Kharchenko, David Sykes
SummaryThe treatment of primary prostate cancer delicately balances an active surveillance approach for low-risk disease with multimodal treatment including surgery, radiation therapy, and hormonal therapy for high-risk disease. Recurrence and develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d477c7edfdcd15d9f7b24e12f8d9997
https://doi.org/10.1101/2022.03.18.484781
https://doi.org/10.1101/2022.03.18.484781
Autor:
Teng Gao, Ruslan Soldatov, Hirak Sarkar, Adam Kurkiewicz, Evan Biederstedt, Po-Ru Loh, Peter Kharchenko
Genome instability and aberrant alterations of transcriptional programs both play important roles in cancer. However, their relationship and relative contribution to tumor evolution and therapy resistance are not well-understood. Single-cell RNA sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7187407c7a0b48ef2e5ccd2508968b6
https://doi.org/10.1101/2022.02.07.479314
https://doi.org/10.1101/2022.02.07.479314
Autor:
Dorsa Toghani, Sharon Zeng, Elmir Mahammadov, Edie I. Crosse, Negar Seyedhassantehrani, Christian Burns, David Gravano, Stefan Radtke, Hans-Peter Kiem, Sonia Rodriguez, Nadia Carlesso, Amogh Pradeep, Nicola K. Wilson, Sarah J. Kinston, Berthold Göttgens, Claus Nerlov, Eric Pietras, Marion Mesnieres, Christa Maes, Atsushi Kumanogoh, Thomas Worzfeld, Peter Kharchenko, David T. Scadden, Antonio Scialdone, Joel A Spencer, Lev Silberstein
Publikováno v:
SSRN Electronic Journal.
SUMMARYTissue stem cells are hierarchically organized. Those that are most primitive serve as key drivers of regenerative response but the signals that selectively preserve their functional integrity are largely unknown. Here, we identify a secreted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ead9460423646c6c024b0a87f5366d6
https://doi.org/10.2139/ssrn.4016764
https://doi.org/10.2139/ssrn.4016764
Autor:
Christa Haase, Karin Gustafsson, Shenglin Mei, Jelena Milosevic, Shu-Chi Yeh, David Sykes, Peter Kharchenko, David Scadden, Charles Lin
Publikováno v:
Experimental Hematology. 100:S51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee60e848e7129694b0109eca1d899f32
https://doi.org/10.1016/j.exphem.2021.12.238
https://doi.org/10.1016/j.exphem.2021.12.238
Autor:
Blue B. Lake, Song Chen, Brandon C. Sos, Jean Fan, Yun Yung, Gwendolyn E. Kaeser, Thu E. Duong, Derek Gao, Jerold Chun, Peter Kharchenko, Kun Zhang
Detailed characterization of the cell types comprising the highly complex human brain is essential to understanding its function. Such tasks require highly scalable experimental approaches to examine different aspects of the molecular state of indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a84d24561e7ed59b01ad4be6867016a
https://doi.org/10.1101/128520
https://doi.org/10.1101/128520
Autor:
Daniel Segrè, Jeremy Zucker, Jeremy Katz, Xiaoxia Lin, Patrik D'Haeseleer, Wayne P. Rindone, Peter Kharchenko, Dat H. Nguyen, Matthew A. Wright, George M. Church
Publikováno v:
OMICS: A Journal of Integrative Biology; Sep2003, Vol. 7 Issue 3, p301-316, 16p