Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Peter K. Wellauer"'
Publikováno v:
The EMBO Journal. 15:4317-4329
We report the isolation of cDNA for the p48 DNA-binding subunit of the heterooligomeric transcription factor PTF1. A sequence analysis of the cDNA demonstrates that p48 is a new member of the family of basic helix-loop-helix (bHLH) transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad9f1b60719039d13cb46e4b5e396601
https://doi.org/10.1002/j.1460-2075.1996.tb00806.x
https://doi.org/10.1002/j.1460-2075.1996.tb00806.x
Autor:
Otto Hagenbüchle, Peter K. Wellauer
Publikováno v:
Nucleic Acids Research. 20:3555-3559
We describe a rapid and general method for isolating DNA-binding proteins in high yield from purified nuclei of animal cells. The method has been tested for the isolation of a series of different DNA-binding activities including those of transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320548e8bcc4431664ae7dc0e1ced0e8
https://doi.org/10.1093/nar/20.14.3555
https://doi.org/10.1093/nar/20.14.3555
Autor:
Liliana Kockel, Otto Hagenbüchle, Peter K. Wellauer, Alexandra Delacour, Alessandra Strom, Pedro Luis Herrera, Virginie Nepote
Publikováno v:
Genesis, Vol. 44, No 6 (2006) pp. 287-296
Mice bearing a Cre-encoding transgene driven by a compound [SV40 small t antigen/mousealpha-amylase-2] promoter expressed the recombinase at early developmental stages broadly in the embryonic endoderm before the pancreas and lungs begin to outgrow,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2472c17d74681af519562ca73612a90
https://pubmed.ncbi.nlm.nih.gov/16786601
https://pubmed.ncbi.nlm.nih.gov/16786601
Autor:
Emma L. Edghill, Graham Goodwin, Peter K. Wellauer, Richard S. Houlston, Karen Barker, Gabrielle S. Sellick, Richard J. Coleman, Christine Garrett, Christina M. Fleischmann, Andrew T. Hattersley, Irene Stolte-Dijkstra, Anna L. Gloyn
Publikováno v:
Nature Genetics, 36(12), 1301-1305. Nature Publishing Group
Individuals with permanent neonatal diabetes mellitus usually present within the first three months of life and require insulin treatment(1,2). We recently identified a locus on chromosome 10p13-p12.1 involved in permanent neonatal diabetes mellitus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf08d298fb1c11c5ad08982e3556a0c2
https://pubmed.ncbi.nlm.nih.gov/15543146
https://pubmed.ncbi.nlm.nih.gov/15543146
Autor:
Andrea Krapp, Catherine Berney, Kurt Bürki, Otto Hagenbüchle, Peter K. Wellauer, Birgit Ledermann, Nicole Zoerkler, Martin Knöfler
We have generated a mouse bearing a null allele of the gene encoding basic helix–loop–helix (bHLH) protein p48, the cell-specific DNA-binding subunit of hetero-oligomeric transcription factor PTF1 that directs the expression of genes in the exocr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b0e55f0749e42e386a26d1fe36cc17
https://europepmc.org/articles/PMC317250/
https://europepmc.org/articles/PMC317250/
Publikováno v:
The Journal of biological chemistry. 271(36)
We have cloned and characterized the rat gene that encodes the p48 DNA-binding subunit of pancreas transcription factor 1 (Ptf1), a cell-specific basic region helix-loop-helix (bHLH) protein. The ptf1-p48 gene measures 1.8 kilobases in size and occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1a9730b1c72655292e80e2f3d2ed3d
https://pubmed.ncbi.nlm.nih.gov/8703005
https://pubmed.ncbi.nlm.nih.gov/8703005
Publikováno v:
Cell. 67(5)
The pancreas-specific transcription factor PTF1 is a heterooligomer that exists as two variants, alpha and beta, both of which bind DNA. The nucleus contains exclusively alpha while the cytoplasm contains both forms. Alpha and beta differ in protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e314320833640aa4a06efbb2e5e3c1d
https://pubmed.ncbi.nlm.nih.gov/1720355
https://pubmed.ncbi.nlm.nih.gov/1720355
Publikováno v:
Journal of Molecular Biology. 182:1-10
Several members of the Amy-2 alpha-amylase multigene family from the CE/J strain of mouse have been cloned in cosmid vectors. Structural analysis of these recombinants reveals that the cloned Amy-2 copies contain tandem 5′ termini. The duplicated 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d49da9ee5b93132c7a32a95a926c07
https://doi.org/10.1016/0022-2836(85)90022-1
https://doi.org/10.1016/0022-2836(85)90022-1
Publikováno v:
Journal of Molecular Biology. 89:397-407
Secondary structure mapping in the electron microscope was applied to ribosomal RNA and precusor ribosomal RNA molecules isolated from nucleoli and the cytoplasm of mouse L-cells. Highly reproducible loop patterns were observed in these molecules. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb729890d16cfd41e69d340e0b163f52
https://doi.org/10.1016/0022-2836(74)90527-0
https://doi.org/10.1016/0022-2836(74)90527-0
Autor:
Igor B. Dawid, Peter K. Wellauer
Publikováno v:
Journal of Molecular Biology. 126:769-782
Sequences in the cloned Drosophila melanogaster rDNA fragments described by Dawid et al. (1978) were compared by heteroduplex mapping. The nontranscribed spacer regions in all fragments are homologous but vary in length. Deletion loops were observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1bf978de5e085811696d92c9e4421d1
https://doi.org/10.1016/0022-2836(78)90019-0
https://doi.org/10.1016/0022-2836(78)90019-0