Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Peter K Park"'
Autor:
Jing Gong, Yajuan Li, Chun-jie Liu, Yu Xiang, Chunlai Li, Youqiong Ye, Zhao Zhang, David H. Hawke, Peter K. Park, Lixia Diao, John A. Putkey, Liuqing Yang, An-Yuan Guo, Chunru Lin, Leng Han
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1968-1981 (2017)
Summary: Increasing evidence has demonstrated that small nucleolar RNAs (snoRNAs) play important roles in tumorigenesis. We systematically investigated the expression landscape and clinical relevance of snoRNAs in >10,000 samples across 31 cancer typ
Externí odkaz:
https://doaj.org/article/343f6a7854ef42bbb2c9e9581b2ab6ed
Autor:
Kevin O. Saunders, Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R. Ryan Meyerhoff, Robert Parks, William E. Walkowicz, Baptiste Aussedat, Nelson R. Wu, Fangping Cai, Yusuf Vohra, Peter K. Park, Amanda Eaton, Eden P. Go, Laura L. Sutherland, Richard M. Scearce, Dan H. Barouch, Ruijun Zhang, Tarra Von Holle, R. Glenn Overman, Kara Anasti, Rogier W. Sanders, M. Anthony Moody, Thomas B. Kepler, Bette Korber, Heather Desaire, Sampa Santra, Norman L. Letvin, Gary J. Nabel, David C. Montefiori, Georgia D. Tomaras, Hua-Xin Liao, S. Munir Alam, Samuel J. Danishefsky, Barton F. Haynes
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2175-2188 (2017)
Summary: Induction of broadly neutralizing antibodies (bnAbs) that target HIV-1 envelope (Env) is a goal of HIV-1 vaccine development. A bnAb target is the Env third variable loop (V3)-glycan site. To determine whether immunization could induce antib
Externí odkaz:
https://doaj.org/article/f020d40e9877461f93e8d9d15c7fa9e4
Autor:
Margaret Beckwith, Daniel Cushman, Tyler Clark, Peter K Park, Taylor Burnham, Robert Burnham, Zachary L McCormick, Aaron Conger
Publikováno v:
Pain Medicine. 24:150-157
Intro. Genicular nerve radiofrequency ablation (GNRFA) is an effective treatment for chronic knee pain related to osteoarthritis. It is often utilized when conservative management has failed and patients wish to avoid arthroplasty, are poor surgical
Autor:
Chunru Lin, Haoqiang Ying, Leng Han, Liuqing Yang, Mien-Chie Hung, David H. Hawke, Jeffrey R. Marks, Yan Zhou, Jianwei Zhou, Shouyu Wang, Tina K. Nguyen, Peter K. Park, Arun Sreekumar, Cristian Coarfa, Nagireddy Putluri, Vasanta Putluri, Feng Jin, Qingsong Hu, Chunlai Li, Yu Xiang, Liang Yan, Ke Liang, Yanyan Zhang, Zhen Xing
Long noncoding RNA (lncRNA) is yet to be linked to cancer metabolism. Here, we report that upregulation of the lncRNA LINC00538 (YIYA) promotes glycolysis, cell proliferation, and tumor growth in breast cancer. YIYA is associated with the cytosolic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c00c8c592d854db5bd3277a268a043f
https://doi.org/10.1158/0008-5472.c.6509790
https://doi.org/10.1158/0008-5472.c.6509790
Autor:
Chunru Lin, Haoqiang Ying, Leng Han, Liuqing Yang, Mien-Chie Hung, David H. Hawke, Jeffrey R. Marks, Yan Zhou, Jianwei Zhou, Shouyu Wang, Tina K. Nguyen, Peter K. Park, Arun Sreekumar, Cristian Coarfa, Nagireddy Putluri, Vasanta Putluri, Feng Jin, Qingsong Hu, Chunlai Li, Yu Xiang, Liang Yan, Ke Liang, Yanyan Zhang, Zhen Xing
Supplementary Figure and Supplementary Figure legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3477a0500d52900a50dcc13fe2a19a
https://doi.org/10.1158/0008-5472.22417233.v1
https://doi.org/10.1158/0008-5472.22417233.v1
Autor:
Zhenqiu Hong, Brian E. Fink, Darpandeep Aulakh, Peng Li, Gregory D. Vite, Xiaoping Hou, Dawn Sun, Aaron Smith, Bei Wang, Amy A. Sarjeant, James Kempson, Arvind Mathur, Lan-Ying Qin, Martins S. Oderinde, Rulin Zhao, Peter K. Park, Lalgudi S. Harikrishnan, Dauh-Rurng Wu, Joseph Pawluczyk, Cornelius Lyndon A M, Huiping Zhang, Janet Caceres-Cortes, Shiuhang Yip, Dharmpal S. Dodd
Publikováno v:
The Journal of organic chemistry. 86(13)
We describe a stereodefined synthesis of the newly identified non-natural phosphorothioate cyclic dinucleotide (CDN) STING agonist, BMT-390025. The new route avoids the low-yielding racemic approach using P(III)-based reagents, and the stereospecific
Autor:
Yinghong Pan, Qingsong Hu, Ke Liang, Vasanta Putluri, Kurt W. Evans, Sri Ramya Donepudi, Abigail S. Caudle, Lieping Chen, David H. Hawke, Jiewei Liu, Youqiong Ye, Aifu Lin, Chunru Lin, Mien Chie Hung, Jing Gong, Gabriel N. Hortobagyi, Jun Yao, Chandrashekar R. Ambati, Yaohua Zhang, Peter K. Park, Cristian Coarfa, Preethi H. Gunaratne, Yajuan Li, Liuqing Yang, Weiya Xia, Leng Han, Michael A. Curran, Dihua Yu, Funda Meric-Bernstam, Li Chuan Chan, Jeffrey R. Marks, Aysegul A. Sahin, Sujash S. Chatterjee, Arun Sreekumar, Nagireddy Putluri, Sergey D. Egranov, Tina K. Nguyen
Publikováno v:
Nature immunology
The mechanisms through which tumor cells genetically lose antigenicity and evade immune checkpoints remain largely elusive. Here, we report that tissue-specific expression of the human long-noncoding RNA LINK-A in mouse mammary glands initiated metas
Autor:
Shirly J. Kuruvila, Peter K. Park, Edwin D. Santiago, Gabriel B. Ayala, Hie Ji Ko, Kieu A. Doan, Tina Marie Briere, Zhifei Wen, Amol J. Ghia
Publikováno v:
Medical Dosimetry. 44:303-308
Spine stereotactic radiosurgery (SSRS) is a noninvasive treatment for metastatic spine lesions. MD Anderson Cancer Center reports a quality assurance (QA) failure rate approaching 15% for SSRS cases, which we hypothesized is due to difficulties in ac
Autor:
Jianwei Zhou, Chunru Lin, Peter K. Park, Yanyan Zhang, Cristian Coarfa, David H. Hawke, Liang Yan, Yu Xiang, Tina Kim Nguyen, Vasanta Putluri, Feng Jin, Haoqiang Ying, Arun Sreekumar, Nagireddy Putluri, Mien Chie Hung, Jeffrey R. Marks, Leng Han, Shouyu Wang, Chunlai Li, Yan Zhou, Qingsong Hu, Liuqing Yang, Zhen Xing, Ke Liang
Publikováno v:
Cancer Research. 78:4524-4532
Long noncoding RNA (lncRNA) is yet to be linked to cancer metabolism. Here, we report that upregulation of the lncRNA LINC00538 (YIYA) promotes glycolysis, cell proliferation, and tumor growth in breast cancer. YIYA is associated with the cytosolic c
Autor:
Matt Soars, Lisa M. Kopcho, Carolyn A. Weigelt, Shilpa Demes, Gregory D. Vite, Mary J. Harner, Rohit Malik, Guo Li, David G. Harden, Charles F. Voliva, Kevin O’Malley, Zheming Ruan, Lan-Ying Qin, Brian J. Arey, Peter K. Park, Jennifer Price, Steven Sheriff, Gerald J. Duke, Ashvinikumar V. Gavai, JIngjing Deng, Brian E. Fink, Christopher M. Barbieri, Max Ruzanov, Muge Celiktas, Mark R. Witmer, Yuval Blat, William D. Schmitz, Joseph G. Naglich, Iyoncy Rodrigo
Publikováno v:
Cancer Research. 81:1140-1140
The chromosome 9p21 (chr9p21) locus is deleted in almost 10% of all cancer types. This locus includes the CDKN2A gene that encodes the critical tumor suppressors p19-ARF and p16-INK4a. Methylthioadenosine phosphorylase (MTAP), a gene proximal to CDKN