Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Peter K Hwang"'
Autor:
Cindy Benod, Rosa Villagomez, Carly S Filgueira, Peter K Hwang, Paul G Leonard, Guillaume Poncet-Montange, Senapathy Rajagopalan, Robert J Fletterick, Jan-Åke Gustafsson, Paul Webb
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99440 (2014)
Nuclear receptors (NRs) are an important group of ligand-dependent transcriptional factors. Presently, no natural or synthetic ligand has been identified for a large group of orphan NRs. Small molecules to target these orphan NRs will provide unique
Externí odkaz:
https://doaj.org/article/137a4a00219b404e842bee770fbb9ed8
Publikováno v:
Traffic. 6:346-350
The clathrin triskelion self-assembles into a lattice that coats transport vesicles participating in several key membrane traffic pathways. A new model of a clathrin lattice at approximately 8 A resolution, generated by Fotin et al. (Nature 2004;432:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::175b66126e0046953444ba520d297d75
https://doi.org/10.1111/j.1600-0854.2005.00277.x
https://doi.org/10.1111/j.1600-0854.2005.00277.x
Publikováno v:
The EMBO Journal. 22:4980-4990
The clathrin triskelion self-assembles into a polyhedral coat surrounding membrane vesicles that sort receptor cargo to the endocytic pathway. A triskelion comprises three clathrin heavy chains joined at their C-termini, extending into proximal and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc169d308349e7178a64b41f74729a5d
https://doi.org/10.1093/emboj/cdg511
https://doi.org/10.1093/emboj/cdg511
Autor:
Robert J. Fletterick, Raymond H. Jacobson, Peter K. Hwang, Paul Webb, Suparna Bhattacharya, Kanagalaghatta R. Rajashankar, Xiaoping Wang, Jan-Åke Gustafsson, Xiaohua Lou
Transcription factor II D (TFIID) is a multiprotein complex that nucleates formation of the basal transcription machinery. TATA binding protein-associated factors 1 and 7 (TAF1 and TAF7), two subunits of TFIID, are integral to the regulation of eukar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53aee0421386100bd2922b2fb636469
https://europepmc.org/articles/PMC4078864/
https://europepmc.org/articles/PMC4078864/
Publikováno v:
Traffic. 1:474-479
We present a summary of the structures of 13 proteins involved in the docking and fusion of intracellular transport vesicles to their target membranes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa3e59a422999397038b9c66aa44aa69
https://doi.org/10.1034/j.1600-0854.2000.010605.x
https://doi.org/10.1034/j.1600-0854.2000.010605.x
Autor:
Shu-Hui Liu, Thomas Earnest, Kai Lin, Joel A. Ybe, Robert J. Fletterick, Kay Hofmann, Lin Chen, Frances M. Brodsky, Peter K. Hwang
Publikováno v:
Nature. 399:371-375
Clathrin is a triskelion-shaped cytoplasmic protein that polymerizes into a polyhedral lattice on intracellular membranes to form protein-coated membrane vesicles. Lattice formation induces the sorting of membrane proteins during endocytosis and orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b803de9daa66ea2841af0c4d30282f8c
https://doi.org/10.1038/20708
https://doi.org/10.1038/20708
Publikováno v:
Journal of Biological Chemistry. 270:13748-13756
Muscle and brain glycogen phosphorylases differ in their responses to activation by phosphorylation and AMP. The muscle isozyme is potently activated by either phosphorylation or AMP. In contrast, the brain isozyme is poorly activated by phosphorylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed026bd49460e366637b69baebe5e97c
https://doi.org/10.1074/jbc.270.23.13748
https://doi.org/10.1074/jbc.270.23.13748
Autor:
Peter K. Hwang, Michael Lane, Benjamin D. Sellers, Robert J. Fletterick, Frances M. Brodsky, Jeremy D. Wilbur, Matthew P. Jacobson, Joel A. Ybe
Summary Clathrin-coated vesicle formation is responsible for membrane traffic to and from the endocytic pathway during receptor-mediated endocytosis and organelle biogenesis, influencing how cells relate to their environment. Generating these vesicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0ede83cc196c36cd05ebac29af4496
https://europepmc.org/articles/PMC2975025/
https://europepmc.org/articles/PMC2975025/
Autor:
Anne E. Goldfeld, Peter K. Hwang, James V. Falvo, Dimitris Thanos, Tom Maniatis, Alla V. Tsytsykova, Charles H. Lin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(50)
The transcription factor NFATp integrates multiple signal transduction pathways through coordinate binding with basic-region leucine zipper (bZIP) proteins and other transcription factors. The NFATp monomer, even in the absence of its activation doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e264ee586797a2c113a0c59eb67d3504
https://pubmed.ncbi.nlm.nih.gov/19060202
https://pubmed.ncbi.nlm.nih.gov/19060202
Autor:
Chih Ying Chen, Peter K. Hwang, Robert J. Fletterick, Jeremy D. Wilbur, Venus Manalo, Frances M. Brodsky
The huntingtin-interacting protein family members (Hip1 and Hip1R in mammals and Sla2p in yeast) link clathrin-mediated membrane traffic to actin cytoskeleton dynamics. Genetic data in yeast have implicated the light chain subunit of clathrin in regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b84e62a1c00849db4efcc3da0134376
https://europepmc.org/articles/PMC2583295/
https://europepmc.org/articles/PMC2583295/