Inner Beauty: Suffering Explained

Autor: Peter Kussell

Publikováno v: Journal of Interdisciplinary History of Ideas, Vol 13, Iss 25 (2024)

This essay is an exploration of the intertextual peregrinations of the Icarus myth. My aim is to trace how the idea of human suffering was taken up in four distinct sub-fields in the history of ideas: its classical origin in Ovid’s Metamorphoses; i

Externí odkaz: https://doaj.org/article/122c55de123b44feaa0126cda44e03ca

Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice

Autor: Verena Untiet, Felix R. M. Beinlich, Peter Kusk, Ning Kang, Antonio Ladrón-de-Guevara, Wei Song, Celia Kjaerby, Mie Andersen, Natalie Hauglund, Zuzanna Bojarowska, Björn Sigurdsson, Saiyue Deng, Hajime Hirase, Nicolas C. Petersen, Alexei Verkhratsky, Maiken Nedergaard

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Astrocytes act as a dynamic Cl− reservoir regulating Cl− homeostasis in the CNS. Astrocytic Cl− is high and stable during sleep, it is lower during wakefulness and fluctuates in response to sensory input and motor activity. Efflux of Cl− from

Externí odkaz: https://doaj.org/article/38d2da81b87c466da2c47d8b24e79713

Distinct patterns of serum and urine macrophage migration inhibitory factor kinetics predict death in sepsis: a prospective, observational clinical study

Autor: Janos Toldi, Leonardo Kelava, Sandor Marton, Diana Muhl, Peter Kustan, Zsolt Feher, Klaudia Maar, Janos Garai, Eszter Pakai, Andras Garami

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Abstract Macrophage migration inhibitory factor (MIF) has been considered as a biomarker in sepsis, however the predictive value of the pattern of its kinetics in the serum and in the urine has remained unclarified. It is also unclear whether the kin

Externí odkaz: https://doaj.org/article/d8b11ea9d2fb45b982159c2d79488989

Impact of elexacaftor/tezacaftor/ivacaftor on lung function, nutritional status, pulmonary exacerbation frequency and sweat chloride in people with cystic fibrosis: real-world evidence from the German CF RegistryResearch in context

Autor: Sivagurunathan Sutharsan, Stefanie Dillenhoefer, Matthias Welsner, Florian Stehling, Folke Brinkmann, Manuel Burkhart, Helmut Ellemunter, Anna-Maria Dittrich, Christina Smaczny, Olaf Eickmeier, Matthias Kappler, Carsten Schwarz, Sarah Sieber, Susanne Naehrig, Lutz Naehrlich, Klaus Tenbrock, Claus Pfannenstiel, Dirk Steffen, Jochen Meister, Britta Welzenbach, Anette Scharschinger, Markus Kratz, Maike Pincus, Tobias Tenenbaum, Mirjam Stahl, Kerstin Landwehr, Stefanie Dillenhöfer, Hans Kössel, Petra Kaiser, Manfred Käding, Simone Stolz, Stefan Blaas, Jutta Hammermann, Monika Gappa, Antje Schuster, Dana Spittel, Sabine Zirlik, Sabina Schmitt, Joachim Bargon, Malte Cremer, Sebastian Fähndrich, Andrea Heinzmann, Lutz Nährlich, Stefan Kuhnert, Sebastian Schmidt, Bettina Wollschläger, Anna Nolde, Inka Held, Wolfgang Kamin, Felix C. Ringshausen, Sabine Wege, Olaf Sommerburg, Norbert Geier, Sara Lisa Fleser, Heinrike Wilkens, Michael Lorenz, Paul Vöhringer, Martin Schebek, Christian Timke, Ingrid Bobis, Thomas Nüßlein, Doris Dieninghoff, Ernst Rietschel, Bastian Klinkhammer, Freerk Prenzel, Alexandra Wald, Axel Kempa, Eva Lücke, Ines Adams, Krystyna Poplawska, Simone Lehmkühler, Monika Bauck, Anne Pfülb, Rainald Fischer, Gudrun Schopper, Susanne Nährig, Matthias Griese, Jörg Grosse, Peter Küster, Birte KinderHolger Köster, Susanne Büsing, Margarethe Pohl, Andreas Artlich, Alexander Kiefer, Manfred Ballmann, Nikola Gjorgjevski, Markus A. Rose, Friederike Ruf, Rolf Mahlberg, Wolfgang Thomas, Ute Graepler, Sebastian Bode, hilipp Meyn, Josef Rosenecker, Cordula Koerner, Klaus-Michael Keller, Tina Teßmer, Helge Hebestreit, Gerhild Lohse

Publikováno v: The Lancet Regional Health. Europe, Vol 32, Iss , Pp 100690- (2023)

Summary: Background: Treatment with elexacaftor/tezacaftor/ivacaftor (ETI) improves multiple clinical outcomes in people with cystic fibrosis (pwCF) with at least one F508del allele. This study evaluated the real-world impact of ETI on lung function,

Externí odkaz: https://doaj.org/article/cb7f1132ad9145b4909f1a838def4b95

2023 DZ2 Planetary Defense Campaign

Autor: Vishnu Reddy, Michael S. Kelley, Lance Benner, Jessie Dotson, Nicolas Erasmus, Davide Farnocchia, Tyler Linder, Joseph R. Masiero, Cristina Thomas, James Bauer, Miguel R. Alarcon, Paolo Bacci, Daniel Bamberger, Adam Battle, Zouhair Benkhaldoun, Guido Betti, Mirel Birlan, Marina Brozovic, Brian Burt, David C. Cantillo, Sunil Chandra, Gregoire Chomette, Ashley Coates, Francesca DeMeo, Maxime Devogèle, Petr Fatka, Marin Ferrais, Paolo Fini, Carel van Gend, Jon D. Giorgini, Dmitry Glamazda, Robert Holmes, Joseph L. Hora, Shinji Horiuchi, Kamil Hornoch, Marco Iozzi, Cristóvão Jacques, Emmanuel Jehin, Hai Jiang, Galina Kaiser, Peter Kušnirák, Eduard Kuznetsov, Julia de León, Alexios Liakos, Javier Licandro, Tim Lister, Jing Liu, Andy Lopez-Oquendo, Martina Maestripieri, Donovan Mathias, Marco Micheli, Shantanu P. Naidu, Alessandro Nastasi, Alin Nedelcu, Elisabeta Petrescu, Marcel Popescu, Stephen B. Potter, Petr Pravec, Juan Sanchez, Toni Santana-Ros, Miquel Serra-Ricart, Nick Sioulas, Adrian Sonka, Alessio Squilloni, Maura Tombelli, Madalina Trelia, David E. Trilling, Elizabeth Warner, Guy Wells, Lorien Wheeler, Mike Wiles

Publikováno v: The Planetary Science Journal, Vol 5, Iss 6, p 141 (2024)

We present the results of a fourth planetary defense exercise, focused this time on the small near-Earth asteroid (NEA) 2023 DZ2 and conducted during its close approach to the Earth in 2023 March. The International Asteroid Warning Network (IAWN), wi

Externí odkaz: https://doaj.org/article/5803dc0c1d9f4ae3b0af7b6a2cfe0c0b