Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Peter Joseph Benedict Helms"'
Publikováno v:
Respiratory Medicine. 109:689-700
Summary Background Airway epithelial cells (AEC) are key contributors to immune function in the lungs but little is known about their role and function in children. Objectives Having previously established that nasal AEC mediator release correlates w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7f7329c892aeaa5ff7f2b4b67bc243
https://doi.org/10.1016/j.rmed.2015.04.001
https://doi.org/10.1016/j.rmed.2015.04.001
Publikováno v:
British Journal of Clinical Pharmacology. 80:844-854
Aims A systematic review of the literature published in English over 10 years was undertaken in order to describe the use of electronic healthcare data in the identification of potential adverse drug reactions (ADRs) in children. Methods MEDLINE and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee6167c6ea0db80fc9fe49f37d36bbb9
https://doi.org/10.1111/bcp.12645
https://doi.org/10.1111/bcp.12645
Autor:
Graham Devereux, Leone C A Craig, Geraldine McNeill, Keith Allan, Bradley Kirby, Peter Joseph Benedict Helms, Anthony Seaton, James S. McLay, Nanda Prabhu, Stephen W Turner, Jon G Ayres
Publikováno v:
European Respiratory Journal. 45:1027-1036
Are maternal vitamin D and E intakes during pregnancy associated with asthma in 10-year-old children?In a longitudinal study of 1924 children born to women recruited during pregnancy, maternal vitamin D intake during pregnancy was assessed by the Foo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ce2a3d2421fcc7f148507c61d8473b
https://doi.org/10.1183/09031936.00102214
https://doi.org/10.1183/09031936.00102214
Publikováno v:
British Journal of Clinical Pharmacology. 78:1143-1150
Aims The aim of this study was to assess opinions of frontline healthcare professionals on the linking of routinely collected national (Scottish) paediatric data for the purpose of identifying earlier signals of adverse drug reactions. Methods Strati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cb7af4ff8d5a2212f8f5afe30f8db45
https://doi.org/10.1111/bcp.12445
https://doi.org/10.1111/bcp.12445
Publikováno v:
Journal of the American Medical Informatics Association. 21:e6-e10
Objective: To review the literature on the views of healthcare professionals to the linkage of healthcare data and to identify any potential barriers and/or facilitators to participation in a data linkage system. Methods: Published papers describing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b5a6d1e1d0dfdaed3592e04b5dfce90
https://doi.org/10.1136/amiajnl-2012-001575
https://doi.org/10.1136/amiajnl-2012-001575
Publikováno v:
Clinical Investigation. 3:433-439
Although research in children can be challenging for investigators, children and their families, it is only through well-designed and ethical studies that improvements in diagnosis, disease prevention and disease management can be made. The Scottish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5dbf3c8ae40fc9e9063245451a60c72
https://doi.org/10.4155/cli.13.22
https://doi.org/10.4155/cli.13.22
Publikováno v:
BMJ Open
OBJECTIVES: The aim was to explore the views of professional stakeholders and healthcare professionals (HCPs) on the linkage of UK National Health Service (NHS) data for paediatric pharmacovigilance purposes and to make recommendations for such a sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175c11dce27c1f8a1da1a1c3b295610d
Publikováno v:
Research in Social & Administrative Pharmacy
Background: Adverse drug events are a major cause of patient safety incidents. Current systems of pharmacovigilance under-report adverse drug reactions (ADRs), especially in children, leading to delays in their identification. This is of particular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898893f29af0f00c1f75a910b43f0c3b
https://openaccess.city.ac.uk/id/eprint/15922/7/1-s2.0-S1551741115001230-main.pdf
https://openaccess.city.ac.uk/id/eprint/15922/7/1-s2.0-S1551741115001230-main.pdf
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 111:396-401
Drug switching is a common medical practice. It indicates continuation of treatment regardless of the reason why the original therapy was stopped and switched. Therefore, the aims of this study were to develop a novel method for determining drug swit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ba9b3932fde0bfa7134e6863eed7be
https://doi.org/10.1111/j.1742-7843.2012.00917.x
https://doi.org/10.1111/j.1742-7843.2012.00917.x
Autor:
Guohua Zhu, Dag E. Undlien, Peter Joseph Benedict Helms, Jorrit Gerritsen, Karin C. Lødrup Carlsen, Moira K. B. Whyte, Sreekumar G. Pillai, Petter Mowinckel, Tale Mæhre Torjussen, Monica Cheng Munthe-Kaas, Kevin V. Shianna, Warren Lenney, Kai-Håkon Carlsen
Publikováno v:
Pediatric Allergy and Immunology. 23:40-49
Background: The CHRNA 3 and 5 genes on chromosome 15 encode the alpha subunits of the nicotinic acetylcholine receptor, mediating airway cholinergic activity. Polymorphisms are associated with cigarette smoking, chronic obstructive pulmonary disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d3b44f5100e9c726831fc4c82ce662d
https://doi.org/10.1111/j.1399-3038.2011.01222.x
https://doi.org/10.1111/j.1399-3038.2011.01222.x