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pro vyhledávání: '"Peter John Richardson"'
Autor:
Daniel P. Smith, Olly Oechsle, Michael J. Rawling, Ed Savory, Alix M.B. Lacoste, Peter John Richardson
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The onset of the 2019 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic necessitated the identification of approved drugs to treat the disease, before the development, approval and widespread administration of suitable vaccines. T
Externí odkaz:
https://doaj.org/article/2fbc02dfda9d46a5b1da373a8184b9af
Autor:
Andrew D MacKinnon, Sabine Mueller, Sara Temelso, Ashirwad Merve, Alan Mackay, Reda Stankunaite, Chris Jones, Daniel P. Smith, Safa Al-Sarraj, Andres Morales La Madrid, Jacques Grill, Adam Donovan, Ofelia Cruz, Mike Hubank, David Sheppard, Cinzia Lavarino, Anne Phelan, Bassel Zebian, Valeria Molinari, Angel M. Carcaboso, Diana Carvalho, Jeremy Pryce, Elizabeth A Corley, Fernando Carceller, Ruth Ruddle, Nagore G. Olaciregui, Akos Pal, Florence I. Raynaud, Peter John Richardson, John P. Overington
Publikováno v:
Cancer Discovery. 12:416-431
Somatic mutations in ACVR1 are found in a quarter of children with diffuse intrinsic pontine glioma (DIPG), but there are no ACVR1 inhibitors licensed for the disease. Using an artificial intelligence–based platform to search for approved compounds