Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Peter Jarzem"'
Pharmacological Treatment of Degenerative Cervical Myelopathy: A Critical Review of Current Evidence
Autor:
Jordan J Levett, Miltiadis Georgiopoulos, Simon Martel, Wissam Al Mugheiry, Nikolaos A. Stavropoulos, Miguel Vega-Arroyo, Carlo Santaguida, Michael H. Weber, Jeff D. Golan, Peter Jarzem, Jean A. Ouellet, Georgios Klironomos, Andreas K. Demetriades
Publikováno v:
Neurospine, Vol 21, Iss 2, Pp 375-400 (2024)
Degenerative cervical myelopathy (DCM) is the leading cause of spinal cord dysfunction in adults, representing substantial morbidity and significant financial and resource burdens. Typically, patients with progressive DCM will eventually receive surg
Externí odkaz:
https://doaj.org/article/5b0182aa252f408d8ad67150213a7db2
Autor:
Matthew Mannarino, Oliver Wu-Martinez, Kai Sheng, Li Li, Rodrigo Navarro-Ramirez, Peter Jarzem, Jean A. Ouellet, Hosni Cherif, Lisbet Haglund
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1257 (2023)
Background: Low back pain is a global health problem directly related to intervertebral disc (IVD) degeneration. Senolytic drugs (RG-7112 and o-Vanillin) target and remove senescent cells from IVDs in vitro, improving tissue homeostasis. One drawback
Externí odkaz:
https://doaj.org/article/e21c59e403a94bd093ec2f44b3e728dc
Autor:
Matthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Peter Jarzem, Michael H. Weber, Jean A. Ouellet, Lisbet Haglund
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background There is an increased level of senescent cells and toll-like teceptor-1, -2, -4, and -6 (TLR) expression in degenerating intervertebral discs (IVDs) from back pain patients. However, it is currently not known if the increase in ex
Externí odkaz:
https://doaj.org/article/7e24cf58fd5b4a58b08120a7b9dddf22
Autor:
Muadh AlZeedi, Salim Al Rawahi, Mashael Muwanis, Thamer M Alraiyes, Humaid Al Farii, Peter Jarzem
Publikováno v:
North American Spine Society Journal, Vol 9, Iss , Pp 100107- (2022)
Background: Total disc replacement as a treatment for degenerative disc disease is gaining increased popularity. There is limited data in the literature about formation of a pseudotumor as a complication following this procedure. We report a very rar
Externí odkaz:
https://doaj.org/article/8ecf7a39f50549e2827019c88133de0e
Publikováno v:
Cells, Vol 11, Iss 22, p 3589 (2022)
Human mesenchymal stem cell (hMSC) and extracellular vesicle (EV) therapy is a promising treatment for discogenic low back pain (LBP). Although promising, major obstacles remain to be overcome. Cellular senescence reduces self-renewal and multipotent
Externí odkaz:
https://doaj.org/article/024d98d234804e659de0666d80ba7d90
Autor:
Ahmed Aoude, Saber Ghadakzadeh, Hamzah Alhamzah, Maryse Fortin, Peter Jarzem, Jean A. Ouellet, Michael H. Weber
Publikováno v:
Asian Spine Journal, Vol 12, Iss 1, Pp 37-46 (2018)
Study DesignThis study was designed as a survey amongst Canadian spine surgeon to determine a scoring system to standardize pedicle screw placement assessment.PurposeThis study aimed to obtain and analyze the opinions of spine surgeons regarding the
Externí odkaz:
https://doaj.org/article/a4febac4e9134d2f8e998be14e26d2de
Publikováno v:
Asian Spine Journal, Vol 12, Iss 1, Pp 94-102 (2018)
Study DesignReliability study.PurposeTo examine the reliability of novice and experienced raters for measurements of the size and composition of the cervical extensor muscles using a thresholding technique.Overview of LiteratureAlthough some authors
Externí odkaz:
https://doaj.org/article/7f5aab3cb74a4c67acad42a9dc576a50
Autor:
Ahmed Aoude, Sultan Aldebeyan, Maryse Fortin, Anas Nooh, Peter Jarzem, Jean A. Ouellet, Michael H. Weber
Publikováno v:
Asian Spine Journal, Vol 11, Iss 6, Pp 880-891 (2017)
Study DesignRetrospective cohort study.PurposeThe purpose of this study was to assess the rate of blood transfusion after cervical fusion surgery, and its effect on complication rates.Overview of LiteratureCervical spine fusions have gained interest
Externí odkaz:
https://doaj.org/article/eae5d8ca24d341bea3459640aae413dd
Autor:
Jeffrey J Hebert, Edward Abraham, Niels Wedderkopp, Erin Bigney, Eden Richardson, Mariah Darling, Hamilton Hall, Charles G Fisher, Y Raja Rampersaud, Kenneth C Thomas, Bradley Jacobs, Michael Johnson, Jerome Paquet, Najmedden Attabib, Peter Jarzem, Eugene K Wai, Parham Rasoulinejad, Henry Ahn, Andrew Nataraj, Alexandra Stratton, Neil Manson
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224200 (2019)
OBJECTIVE:Identify patient subgroups defined by trajectories of pain and disability following surgery for degenerative lumbar spinal stenosis, and investigate the construct validity of the subgroups by evaluating for meaningful differences in clinica
Externí odkaz:
https://doaj.org/article/e59a1cb5625143a7a80619ad6d4132b4
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 7, Pp 15118-15135 (2015)
Painful degeneration of soft tissues accounts for high socioeconomic costs. Tissue engineering aims to provide biomimetics recapitulating native tissues. Biocompatible thermoplastics for 3D printing can generate high-resolution structures resembling
Externí odkaz:
https://doaj.org/article/7d91ac40f9464d038c6ddd75b3d50387