Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Peter J. Wyld"'
Autor:
Peter J. Wyld, Paul Rolan, Kelvin R. Palmer, Irving S. Benjamin, Peter M. Lloyd, F. Mullins, Felix Waldmeier, Gerard Flesch, Laurence J. Brookman, Antoine Sioufi
Publikováno v:
Clinical Pharmacology & Therapeutics. 62:272-278
Objectives Valsartan (CGP 48933), an orally active angiotensin II antagonist, is eliminated mainly by hepatic clearance. To characterize the compound(s) excreted in the bile, biliary excretion of valsartan was investigated by collection of bile after
Autor:
Peter J. Wyld
Publikováno v:
Journal of the Royal Society of Medicine. 76(4)
Autor:
Anna Pluzanska, Peter J. Wyld, Magdolna Dank, Raquel Lang, Dominique Becquart, Robert S. Smith, Ramon Perez-Carrion, Poonamalle P. Bapsy, Eeva Salminen, Corrado Boni, Henning T. Mouridsen, Mikhail Gershanovich, Yan Sun, H. A. Chaudri-Ross, Fritz Jaenicke, Harm Sleeboom, Justus Apffelstaedt, Alain Monnier, Ajay Bhatnagar, Raymond Snyder
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 21(11)
Purpose: To analyze overall survival (OS) and update efficacy data for letrozole versus tamoxifen as first-line therapy in postmenopausal women with locally advanced or metastatic breast cancer. Patients and Methods: This multicenter phase III trial
Autor:
Marie-Edith Anne Bonneterre, Austin James Combest, Ashley Erickson Simmons, Paulina Zelenay McAtee, J. Balkissoon, Peter J. Wyld, Angelena Moseley, Dirk J. Reitsma
Publikováno v:
Journal of Clinical Oncology. 32:e12526-e12526
e12526 Background: HER2 targeting in gastric cancer (GC) is a relatively new approach. The ToGA trial demonstrated the importance of HER2 over-expression in GC. Unlike breast cancer, little informa...
Autor:
Katherine M. Cooper, Jean L. Simmons, Lester I. Harrison, Peter J. Wyld, Bruce P. Ekholm, David Donnell
Publikováno v:
The Journal of pharmacy and pharmacology. 48(6)
A 28-day double-blind parallel group study has been conducted to compare the safety and tolerability of HFA-134a, a chlorofluorocarbon-free propellant in a pressurized metered-dose inhaler (MDI A), with a chlorofluorocarbon propellant (MDI C). Sixtee
Autor:
Quentin Campbell-Hewson, Darren Hargrave, Victoria Lock, John Lyons, Peter J. Wyld, Sarah Halford, Alan V. Boddy, Murray Yule, Martin Elliott, Bruce Morland, Andrew D.J. Pearson, Guy Makin, Lucas Moreno
Publikováno v:
Journal of Clinical Oncology. 30:9542-9542
9542 Background: AT9283, is a multi-targeted inhibitor, against Aurora A and B, JAK & ABL kinases. Aurora kinases are potential therapeutic targets in paediatric solid cancers. Methods: A phase I dose escalation study was performed using a 72 hour in
Publikováno v:
Cancer. 54:48-53
Two patients fulfilled the clinical and hematologic criteria for B-cell acute lymphoblastic leukemia: the malignant cells had L3 morphology, bore B-cell markers, and carried the specific t(8;14) translocation. The leukemic cells of one patient were t