Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Peter J. Syribeys"'
Autor:
John Vernachio, Jeff T. Hutchins, Andrea Hall, Paul Domanski, Elena Gorovits, Brenda Ames, Cathy Y. Chang, Joseph M. Patti, Peter J. Syribeys
Publikováno v:
Microbial Pathogenesis. 43:55-66
Enterococci are opportunistic pathogens known to cause numerous clinical infections and complications in humans. Adhesin-mediated binding to extracellular matrix (ECM) proteins of the host is thought to be a crucial step in the pathogenesis of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b0a7a950a94e9627d5821b66caa749
https://doi.org/10.1016/j.micpath.2007.03.003
https://doi.org/10.1016/j.micpath.2007.03.003
Autor:
Joseph M. Patti, Bradley D. Prater, Brenda Ames, Yule Liu, John Vernachio, Elena Gorovits, Peter J. Syribeys
Publikováno v:
Infection and Immunity. 72:6237-6244
Staphylococcus capitis ( S. capitis ) has been implicated in a large proportion of coagulase-negative staphylococcal infections in very-low-birth-weight infants. To identify potential therapeutic targets, the S. capitis genome was probed for the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c434fe55e8057cb960ec6b8a6e338a
https://doi.org/10.1128/iai.72.11.6237-6244.2004
https://doi.org/10.1128/iai.72.11.6237-6244.2004
Autor:
Edward O. Yonter, Magnus Höök, Rick A. Wetsel, Lawrence Y. L. Lee, Eric L. Brown, Peter J. Syribeys, John Vernachio, David L. Haviland
Publikováno v:
The Journal of Infectious Diseases. 190:571-579
Staphylococcus aureus can cause a variety of acute and chronic diseases. The ability of S. aureus to cause persistent infections has been linked to its ability to evade or inactivate host immune responses. We have identified a secreted 19-kDa protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb73b580be514d8380b6b25e2129a7af
https://doi.org/10.1086/422259
https://doi.org/10.1086/422259
Autor:
Andrea Hall, Patel Pratisksha, Jeff T. Hutchins, Michael A. Johnson, Julia M. Ross, John Vernachio, Elena Gorovits, Paul Domanski, Peter J. Syribeys, Joseph M. Patti
Publikováno v:
Infection and Immunity. 71:6864-6870
The Staphylococcus aureus MSCRAMM (microbial surface components recognizing adhesive matrix molecules) protein clumping factor A (ClfA) has been shown to be a critical virulence factor in several experimental models of infection. This report describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367b6aa8c95c9be6c49a417e84773913
https://doi.org/10.1128/iai.71.12.6864-6870.2003
https://doi.org/10.1128/iai.71.12.6864-6870.2003
Autor:
Amy Schneider, Thuan P. Le, John Vernachio, Brenda Ames, Bradley D. Prater, Yin-Li Chai, Peter J. Syribeys, Joseph M. Patti, Jeff Robbins, Arnold S. Bayer
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:3400-3406
SA-IGIV is a human polyclonal immunoglobulin containing elevated levels of antibodies specific for the fibrinogen-binding MSCRAMM protein clumping factor A (ClfA). In vitro, SA-IGIV specifically recognized ClfA that was expressed on the surface ofSta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77814b70dd4723d6a2bb9ff744db4f1
https://doi.org/10.1128/aac.47.11.3400-3406.2003
https://doi.org/10.1128/aac.47.11.3400-3406.2003
Autor:
Peter J. Syribeys, Paul Domanski, Andrea Hall, Elena Gorovits, Jeff T. Hutchins, Patel Pratisksha, John Vernachio, Bradley D. Prater, Joseph M. Patti
Publikováno v:
Hybridoma (2005). 26(1)
Staphylococcus epidermidis is an important opportunistic human pathogen that has recently emerged as a major cause of foreign-body infections. The most important stage contributing to the pathogenesis of this bacteria is the initial adherence to host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfc878c9480b1283757ef8b2736f403
https://pubmed.ncbi.nlm.nih.gov/17316083
https://pubmed.ncbi.nlm.nih.gov/17316083
Autor:
Dawn Bryant, Bradley D. Prater, Joseph M. Patti, Brenda Ames, Elena Gorovits, John Vernachio, Arnold S. Bayer, Peter J. Syribeys
A human donor-selected immunoglobulin G for intravenous injection (IGIV) product with elevated titers against the staphylococcal fibrinogen-binding MSCRAMM proteins ClfA and SdrG (INH-A21) was tested in vitro and in vivo. INH-A21 contained a signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c3de7a15a292d321875ce6b728e8af
https://europepmc.org/articles/PMC1366878/
https://europepmc.org/articles/PMC1366878/
Autor:
John Vernachio, Andrea Hall, Peter J. Syribeys, Paul Domanski, Li Zhang, Joseph M. Patti, Elena Gorovits, Dawn Bryant, Patel Pratisksha, Jeff T. Hutchins, Arnold S. Bayer
We report the humanization and characterization of monoclonal antibody (MAb) T1-2 or tefibazumab, a monoclonal antibody that recognizes clumping factor A expressed on the surface of Staphylococcus aureus . We demonstrate that the binding kinetics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af08b81772fd9fd9b98d556eeb5a231a
https://europepmc.org/articles/PMC1201235/
https://europepmc.org/articles/PMC1201235/