Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Peter J. Reiser"'
Autor:
Douglas R. Moellering, Kelley Smith-Johnston, Christian Kelley, Melissa J. Sammy, Jason Benedict, Guy Brock, Jillian Johnson, Kedryn K. Baskin, Wael N. Jarjour, Martha A. Belury, Peter J. Reiser, Prabhakara R. Nagareddy, Beatriz Y. Hanaoka
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Insulin resistance affects a substantial proportion of patients with rheumatoid arthritis (RA). Skeletal muscle mitochondrial dysfunction results in the accumulation of lipid intermediates that interfere with insulin signaling. We
Externí odkaz:
https://doaj.org/article/9fb94adc1c0b4699a29dab1d74a767ad
Autor:
Peter J. Reiser, Paul M. L. Janssen
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/8c4945a2c034430c94987cecb14e30d6
Autor:
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Cory S. Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Small molecule cardiac troponin activators could potentially enhance cardiac muscle contraction in the treatment of systolic heart failure. We designed a small molecule, RPI-194, to bind cardiac/slow skeletal muscle troponin (Cardiac muscle and slow
Externí odkaz:
https://doaj.org/article/756603ce756d47d9bebb8a3a2a2a53cd
Autor:
Peter J. Reiser, Paul M. L. Janssen
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/d464c3ca68d9475391b34ea03cae1fe5
Autor:
Eric R. Hantz, Svetlana B. Tikunova, Natalya Belevych, Jonathan P. Davis, Peter J. Reiser, Steffen Lindert
Publikováno v:
bioRxiv
Despite large investments from academia and industry, heart failure, which results from a disruption of the contractile apparatus, remains a leading cause of death. Cardiac muscle contraction is a calcium-dependent mechanism, which is regulated by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578c04f314b7a447cbb16c91c643237c
https://europepmc.org/articles/PMC9934531/
https://europepmc.org/articles/PMC9934531/
Autor:
Samantha R. Queeno, Peter J. Reiser, Caley M. Orr, Terence D. Capellini, Kirstin N. Sterner, Matthew C. O'Neill
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 281:111415
Autor:
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Corey Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Richard Schulz, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Journal of Comparative Physiology B. 189:717-734
In marine mammals, muscular development has been identified as a rate-limiting factor in achieving adult dive capacities. This study investigates the rate that myosin heavy chain (MHC) composition matures in a postural and locomotor skeletal muscle f
Autor:
Paul M.L. Janssen, Peter J. Reiser
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology, Vol 11 (2020)
Autor:
Andres F. Cuesta, Peter J. Reiser, Monica X. Li, Peter M. Hwang, Jonathan P. Davis, Morgan V. Price, Natalya Belevych, Svetlana B. Tikunova, Brandon J. Biesiadecki
Publikováno v:
The Journal of General Physiology
Cardiac troponin activators could be beneficial in systolic heart failure. Tikunova et al. demonstrate that, unlike previously known calcium sensitizers, the small molecule 3-chlorodiphenylamine does not activate isolated cardiac troponin C but inste