Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Peter J. O'Shaughnessy"'
Autor:
Liza O’Donnell, Laura F. Dagley, Michael Curley, Annalucia Darbey, Peter J. O’Shaughnessy, Thorsten Diemer, Adrian Pilatz, Daniela Fietz, Peter G. Stanton, Lee B. Smith, Diane Rebourcet
Publikováno v:
PLoS ONE, Vol 18, Iss 9 (2023)
Sertoli cells support the development of sperm and the function of various somatic cells in the interstitium between the tubules. Sertoli cells regulate the function of the testicular vasculature and the development and function of the Leydig cells t
Externí odkaz:
https://doaj.org/article/b12856a5a9754a999cd00b7cc1ae9dd5
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract Objective Steroid hormones are responsible for the control of a wide range of physiological processes such as development, growth, reproduction, metabolism, and aging. Because of the variety of enzymes, substrates and products that take part
Externí odkaz:
https://doaj.org/article/8b179297a1f64a8396ad084b065eee14
Autor:
Zoe C. Johnston, Michelle Bellingham, Panagiotis Filis, Ugo Soffientini, Denise Hough, Siladitya Bhattacharya, Marc Simard, Geoffrey L. Hammond, Peter King, Peter J. O’Shaughnessy, Paul A. Fowler
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth the adrenals are essential for neonate salt retention through secretion of
Externí odkaz:
https://doaj.org/article/884a4e21a4714467b1d19fd81a10cfae
Autor:
Pablo Capilla-Lasheras, Davide M. Dominoni, Simon A. Babayan, Peter J. O'Shaughnessy, Magdalena Mladenova, Luke Woodford, Christopher J. Pollock, Tom Barr, Francesco Baldini, Barbara Helm
Publikováno v:
Frontiers in Ecology and Evolution, Vol 5 (2017)
Urban and forest habitats differ in many aspects that can lead to modifications of the immune system of wild animals. Altered parasite communities, pollution, and artificial light at night in cities have been associated with exacerbated inflammatory
Externí odkaz:
https://doaj.org/article/5f256a2e898b4e9782cfb6d4dce8242e
Autor:
Peter J O'Shaughnessy, Jean Philippe Antignac, Bruno Le Bizec, Marie-Line Morvan, Konstantin Svechnikov, Olle Söder, Iuliia Savchuk, Ana Monteiro, Ugo Soffientini, Zoe C Johnston, Michelle Bellingham, Denise Hough, Natasha Walker, Panagiotis Filis, Paul A Fowler
Publikováno v:
PLoS Biology, Vol 17, Iss 2, p e3000002 (2019)
Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen
Externí odkaz:
https://doaj.org/article/4dcdf7a075af42d591b0e1daf4f6113a
Autor:
Diane Rebourcet, Ana Monteiro, Lyndsey Cruickshanks, Nathan Jeffery, Sarah Smith, Laura Milne, Peter J O'Shaughnessy, Lee B Smith
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219524 (2019)
ObjectivesThe current study aims to identify markers that would reflect the number of Leydig cells present in the testis, to help determine whether labour-intensive methods such as stereology are necessary. We used our well-characterised Sertoli cell
Externí odkaz:
https://doaj.org/article/e9650f18fd44449583ca01c5a02eae31
Publikováno v:
Current Opinion in Endocrine and Metabolic Research. 6:42-48
Since Enrico Sertoli's first depiction of Sertoli cells in the 19th century, the role of Sertoli cells as a hub for both testis biology and as a potential therapeutic tool, continues to grow. The function of Sertoli cells in the orchestration of test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb4891290174d837bf8032733fa2c98e
https://doi.org/10.1016/j.coemr.2019.04.003
https://doi.org/10.1016/j.coemr.2019.04.003
Autor:
Diane Rebourcet, Peter J O'Shaughnessy, Ana Monteiro, Laura Milne, Lyndsey Cruickshanks, Nathan Jeffrey, Florian Guillou, Tom C Freeman, Rod T Mitchell, Lee B Smith
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105687 (2014)
The Sertoli cells are critical regulators of testis differentiation and development. In the adult, however, their known function is restricted largely to maintenance of spermatogenesis. To determine whether the Sertoli cells regulate other aspects of
Externí odkaz:
https://doaj.org/article/02d3787fbc174929a7cbb0de59766329
Autor:
Peter G. Stanton, Lee B. Smith, Julien M. D. Legrand, Giuseppe Infusini, Frédéric Chalmel, Diane Rebourcet, Andrew I. Webb, Raouda Sgaier, Laura F. Dagley, Adrian Pilatz, Robin M. Hobbs, Wolfgang Weidner, Liza O'Donnell, Robert I McLachlan, Thorsten Diemer, Daniela Fietz, Peter J. O'Shaughnessy
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
FASEB Journal, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
The FASEB Journal
FASEB J
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
FASEB Journal, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
The FASEB Journal
FASEB J
International audience; Sperm develop from puberty in the seminiferous tubules, inside the blood-testis barrier to prevent their recognition as "non-self" by the immune system, and it is widely assumed that human sperm-specific proteins cannot access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fa447f4187acfb621b5d367509ed92
https://hal.archives-ouvertes.fr/hal-03169602
https://hal.archives-ouvertes.fr/hal-03169602
Autor:
Els Atema, Kees van Oers, Christa Mateman, Maaike de Jong, Michelle Bellingham, Peter J. O'Shaughnessy, Lisa Trost, Gavin Blackburn, Barbara Helm, Marcel E. Visser, Pietro B. D'Amelio, Davide M. Dominoni, Jessica Clark
Globally increasing levels of artificial light at night (ALAN) are associated with shifts in circadian rhythms of behaviour in many wild species. However, it is still unclear whether changes in behavioural timing are underlined by parallel shifts in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61f68106ec3e49a7f192d2e8e0341df7
https://doi.org/10.1101/2020.12.18.423473
https://doi.org/10.1101/2020.12.18.423473