Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Peter J. Nijweide"'
Publikováno v:
Current Osteoporosis Reports. 1:5-10
The osteocyte is the most abundant cell type of bone. There are approximately 10 times as many osteocytes as osteoblasts in adult human bone, and the number of osteoclasts is only a fraction of the number of osteoblasts. Our current knowledge of the
Publikováno v:
Histochemistry and Cell Biology. 106:495-501
Cultures of isolated osteocytes may offer an appropriate system to study osteocyte function, since isolated osteocytes in culture behave very much like osteocytes in vivo. In this paper we studied the capacity of osteocytes to change their surroundin
Autor:
Peter J. Nijweide, Jenneke Klein-Nulend, T. Vrijheid-Lammers, N.E. Ajubi, Elisabeth H. Burger, M. J. Alblas
Publikováno v:
Biochemical and Biophysical Research Communications. 225:62-68
It has been postulated that the transduction of mechanical stress signals to bone cells occurs via loading-dependent flow of interstitial fluid through the lacuno-canalicular network of bone. We have shown earlier that chicken osteocytes release enha
Publikováno v:
The Journal of Nutrition. 125:2020S-2023S
Although osteocytes are by far the most abundant cell type of bone, they are least understood in terms of function and regulation. Previous studies have concentrated on their possible role as mobilizers of bone calcium, via the process of osteocytic
Publikováno v:
Pflügers Archiv. 429:663-671
Many cell types respond to mechanical membrane perturbation with intracellular Ca2+ responses. Stretch-activated (SA) ion channels may be involved in such responses. We studied the occurrence as well as the underlying mechanisms of cell membrane stre
Publikováno v:
Ultrasound in Medicine & Biology. 21:121-127
The effect of therapeutic doses of ultrasound was tested on endochondral ossification of in vitro developing metatarsal long bone rudiments of 16- and 17-day-old fetal mice. Bone growth, calcification and resorption following exposure to several dose
Publikováno v:
Bone. 16:171-177
Investigating the potentiality of cord monocytes to differentiate toward osteoclast-like cells (OCL) in vitro, we previously reported that in the presence of 1,25(OH)2 vitamin D3 (1,25-(OH)2D3), multinucleated-cells generated by cord monocyte culture
Autor:
Dirk L. Ypey, B. van Duijn, M. P. M. Herrmann-Erlee, A. van der Plas, J. M. van der Meer, Peter J. Nijweide, A Maassen van den Brink, A. Wiltink, Peter H.G.M. Willems
Publikováno v:
Cell Calcium. 14:591-600
The present study evaluates the effect of parathyroid hormone (PTH) on intracellular calcium. Intracellular calcium ion concentrations ([Ca2+]i) in fetal rat osteoblasts in primary culture (ROB) and in UMR106-01 osteogenic sarcoma cells were monitore
Autor:
Dirk L. Ypey, Peter J. Nijweide, Arnoud van der Laarse, Karin M. Höld, Adam F. Weidema, Arie van der Plas, Jan H. Ravesloot
Publikováno v:
Journal of bone and mineral research, 7(2 S), S377-S387. Wiley-Blackwell
Embryonic chick bone cells express various types of ionic channels in their plasma membranes for as yet unresolved functions. Chick osteoclasts (OCL) have the richest spectrum of channel types. Specific for OCL is a K+ channel, which activates (opens
Autor:
Takuya Sato, Tetsu Matsuo, Mitsue Ohta, Kenichi Tezuka, Yoshiyuki Hakeda, Kayo Tanaka, Peter J. Nijweide, Noriyoshi Kurihara, Hiroshi Kamioka, Masayoshi Kumegawa
Publikováno v:
Biochemical and Biophysical Research Communications. 186:911-917
Bone remodeling is a complex process coupling bone formation and resorption. Osteoblasts, the bone-forming cells, are known to produce various bone matrix proteins and cytokines; however, little is known about protein factors produced by osteoclasts