Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Peter J. Meek"'
Publikováno v:
Current Proteomics. 5:181-190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb537e15872603c0d7bb53ae60ef9ff
https://doi.org/10.2174/157016408785909677
https://doi.org/10.2174/157016408785909677
Publikováno v:
Drug Discovery Today. 11:895-904
Identifying potential lead molecules is becoming a more automated process. We review Shape Signatures, a tool that is effective and easy to use compared with most computer aided drug design techniques. Laboratory researchers can apply this in silico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f968e280880d37d64bf559b17699b14
https://doi.org/10.1016/j.drudis.2006.08.014
https://doi.org/10.1016/j.drudis.2006.08.014
Autor:
John B C Findlay, Graham Whyteside, Michael A. Harrison, Malcolm E. Finbow, Stephen K Ball, Peter J Meek, Terence P. Kee, Neil Dixon
Publikováno v:
Biochemistry. 44:15024-15031
The macrolide antibiotic concanamycin is a potent and specific inhibitor of the vacuolar H(+)-ATPase (V-ATPase), binding to the V(0) membrane domain of this eukaryotic acid pump. Although binding is known to involve the 16 kDa proteolipid subunit, co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cd0c88860de97767278196bbf37ed4
https://doi.org/10.1021/bi051529h
https://doi.org/10.1021/bi051529h
Publikováno v:
Pharmaceutical Sciences Encyclopedia ISBN: 9780470571224
Pharmaceutical Sciences Encyclopedia
Pharmaceutical Sciences Encyclopedia
Defining similarity between molecules is a complex task. There is a vast expanse of in silico techniques that “detect” similarity between small molecules. In silico search techniques prove most useful when the similarity measurement (scoring inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::738b85ca9565a73ee7498aedb4eb0f90
https://doi.org/10.1002/9780470571224.pse032
https://doi.org/10.1002/9780470571224.pse032
