Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Peter J. Maniak"'
Autor:
Yotesawee Srisomboon, Noriyuki Ohkura, Koji Iijima, Takao Kobayashi, Peter J. Maniak, Hirohito Kita, Scott M. O’Grady
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9071 (2021)
Polyethyleneimine (PEI) induced immune responses were investigated in human bronchial epithelial (hBE) cells and mice. PEI rapidly induced ATP release from hBE cells and pretreatment with glutathione (GSH) blocked the response. PEI activated two cond
Externí odkaz:
https://doaj.org/article/81129f8e72ec4fafabe821ebfe81b4fc
Autor:
Yotesawee Srisomboon, Koji Iijima, Mathia Colwell, Peter J. Maniak, Marissa Macchietto, Christopher Faulk, Hirohito Kita, Scott M. O’Grady
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:494-508.e6
Alternaria alternata and house dust mite exposure evokes IL-33 secretion from the airway epithelium, which functions as an alarmin to stimulate type 2 immunity. Extracellular DNA (eDNA) is also an alarmin that intensifies inflammation in cystic fibro
Autor:
Takao Kobayashi, Peter J. Maniak, Koji Iijima, Scott M. O'Grady, Noriyuki Ohkura, Hirohito Kita, Yotesawee Srisomboon
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9071, p 9071 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
Polyethyleneimine (PEI) induced immune responses were investigated in human bronchial epithelial (hBE) cells and mice. PEI rapidly induced ATP release from hBE cells and pretreatment with glutathione (GSH) blocked the response. PEI activated two cond
Publikováno v:
J Physiol
Key points Alternaria aeroallergens induce the release of ATP from human bronchial epithelial (HBE) cells by activating a conductive pathway involving voltage-dependent anion channel-1 (VDAC-1) and by exocytosis of ATP localized within membrane vesic
Autor:
Diane L. Squillace, Koji Iijima, Nandadevi Patil, Peter J. Maniak, Scott M. O'Grady, Hirohito Kita, Erik L. Anderson, Masaru Uchida
Publikováno v:
Allergy. 72:1521-1531
Background Interleukin (IL)-33 is implicated in the pathophysiology of asthma and allergic diseases. However, our knowledge is limited regarding how IL-33 release is controlled. The transcription factor nuclear factor-erythroid-2-related factor 2 (Nr
Publikováno v:
The FASEB Journal. 33
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 310:L50-L58
Carvedilol functions as a nonselective β-adrenergic receptor (AR)/α1-AR antagonist that is used for treatment of hypertension and heart failure. Carvedilol has been shown to function as an inverse agonist, inhibiting G protein activation while stim
Publikováno v:
American Journal of Physiology-Cell Physiology. 309:C847-C855
Human airway epithelial cells express β-adrenergic receptors (β-ARs), which regulate mucociliary clearance by stimulating transepithelial anion transport and ciliary beat frequency. Previous studies using airway epithelial cells showed that stimula
Autor:
Chatsri Deachapunya, Scott M. O'Grady, Yotesawee Srisomboon, Nathan A. Zaidman, Peter J. Maniak
The objective of this study was to determine the molecular identity of ion channels involved in K+ secretion by the mammary epithelium and to examine their regulation by purinoceptor agonists. Apical membrane voltage-clamp experiments were performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4c3c2097011f3593293fc85b7ab4af
https://europepmc.org/articles/PMC6008065/
https://europepmc.org/articles/PMC6008065/
Autor:
Nandadavi Patil, Tamene Melkamu, Peter J. Maniak, Cheryl A. Lancto, Hirohito Kita, Scott M. O'Grady
Publikováno v:
The Journal of Physiology. 591:4595-4609
Exposure of human bronchial epithelial (HBE) cells from normal and asthmatic subjects to extracts from Alternaria alternata evoked a rapid and sustained release of ATP with greater efficacy observed in epithelial cells from asthmatic patients. Previo