Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Peter J. M. Wilson"'
Autor:
Peter J. M. Wilson, Lakshminarayan R. Ranganath, George Bou‐Gharios, James A. Gallagher, Juliette H. Hughes
Publikováno v:
JIMD Reports, Vol 58, Iss 1, Pp 52-60 (2021)
Abstract Alkaptonuria (AKU) is caused by homogentisate 1,2‐dioxygenase (HGD) deficiency. This study aimed to determine if HGD and other enzymes related to tyrosine metabolism are associated with the location of ochronotic pigment. Liver, kidney, sk
Externí odkaz:
https://doaj.org/article/ec5232cb22854f4187c69420010d3314
Autor:
Brendan P. Norman, Andrew S. Davison, Bryony Hickton, Gordon A. Ross, Anna M. Milan, Andrew T. Hughes, Peter J. M. Wilson, Hazel Sutherland, Juliette H. Hughes, Norman B. Roberts, George Bou-Gharios, James A. Gallagher, Lakshminarayan R. Ranganath
Publikováno v:
Metabolites, Vol 12, Iss 10, p 927 (2022)
Metabolomic analyses in alkaptonuria (AKU) have recently revealed alternative pathways in phenylalanine-tyrosine (phe-tyr) metabolism from biotransformation of homogentisic acid (HGA), the active molecule in this disease. The aim of this research was
Externí odkaz:
https://doaj.org/article/e39b7f67a9a743138b22b940540aaf21
Autor:
Jane P, Dillon, Victoria J, Waring-Green, Adam M, Taylor, Peter J M, Wilson, Mark, Birch, Alison, Gartland, James A, Gallagher
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 816
Osteoblast cultures can be used to investigate the mechanisms of bone formation, to probe the cellular and molecular basis of bone disease, and to screen for potential therapeutic agents that affect bone formation. Here, we describe the methods for e