Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Peter J. Kim"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The lysosomal protein TMEM106B was identified as a risk modifier of multiple dementias including frontotemporal dementia and Alzheimer’s disease. The gene comes in two major haplotypes, one associated with disease risk, and by comparison, the other
Externí odkaz:
https://doaj.org/article/ac3f8cd9009243edb4a2e96bbb2cac97
Autor:
Tingting Zhang, Weilun Pang, Tuancheng Feng, Jennifer Guo, Kenton Wu, Mariela Nunez Santos, Akshayakeerthi Arthanarisami, Alissa L. Nana, Quynh Nguyen, Peter J. Kim, Joanna L. Jankowsky, William W. Seeley, Fenghua Hu
Publikováno v:
Science advances, vol 9, iss 18
TMEM106B, a lysosomal transmembrane protein, has been closely associated with brain health. Recently, an intriguing link between TMEM106B and brain inflammation has been discovered, but how TMEM106B regulates inflammation is unknown. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b10a012b9f2292823f38252b702b9a
https://doi.org/10.1126/sciadv.add2676
https://doi.org/10.1126/sciadv.add2676
Autor:
George A. Edwards, Caleb A. Wood, Quynh Nguyen, Peter J. Kim, Ruben Gomez-Gutierrez, Kyung-Won Park, Cody Zurhellen, Ismael Al-Ramahi, Joanna L. Jankowsky
Publikováno v:
bioRxiv
TMEM106B is a risk modifier for a growing list of age-associated dementias including Alzheimer’s and frontotemporal dementia, yet its function remains elusive. Two key questions that emerge from past work are whether the conservative T185S coding v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35efc887c352c91bc32018a12862200
https://europepmc.org/articles/PMC10055407/
https://europepmc.org/articles/PMC10055407/
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26536 (2011)
Marginal zone B cells (MZB) mount a rapid antibody response, potently activate naïve T cells, and are enriched in autoreactive B cells. MZBs express high levels of CD1d, the restriction element for invariant natural killer T cells (iNKT). Here, we e
Externí odkaz:
https://doaj.org/article/3a77ff2020e248a7bfaea01b26896121
Autor:
Nikhita D. Mansukhani, Linda M. Guiney, Mark C. Hersam, Eduardo Larios, Diego Alducin, Arturo Ponce, Yichao Zhao, Miguel Jose Yacaman, Peter J. Kim
Publikováno v:
Small. 12:294-300
Conditions for the dispersion of molybdenum disulfide (MoS2) in aqueous solution at concentrations up to 0.12 mg mL(-1) using a range of nonionic, biocompatible block copolymers (i.e., Pluronics and Tetronics) are identified. Furthermore, the optimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21936cdb453c5682b7b3e972fcffb1c3
https://doi.org/10.1002/smll.201503082
https://doi.org/10.1002/smll.201503082
Autor:
Ann-Jay Tong, William H. McBride, Prabhat Kumar Purbey, Keisuke S. Iwamoto, Philip O. Scumpia, Stephen T. Smale, Peter J. Kim
Publikováno v:
Immunity, vol 47, iss 3
Summary Environmental insults are often detected by multiple sensors that activate diverse signaling pathways and transcriptional regulators, leading to a tailored transcriptional output. To understand how a tailored response is coordinated, we exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a067b7cc9c149ce487e0bcdfc77e08e
https://escholarship.org/uc/item/8mr7200g
https://escholarship.org/uc/item/8mr7200g
Publikováno v:
Clinical and Experimental Immunology. 173:18-27
Summary Patients with systemic lupus erythematosus (SLE) display reduced numbers and functions of invariant natural killer T (iNK T) cells, which are restored upon treatment with corticosteroids and rituximab. It is unclear whether the iNK T cell ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d352aef08fb2773fcf04d1dac83d015e
https://doi.org/10.1111/cei.12079
https://doi.org/10.1111/cei.12079
Autor:
Syed F. Ali, Nina M. Shinday, Jerrold S. Meyer, Brian J. Piper, Dominik Biezonski, Peter J. Kim
Publikováno v:
European Journal of Pharmacology. 701:176-180
Although the recreational drug 3,4-methylenedioxymethamphetamine (MDMA) is often described as a selective serotonergic neurotoxin, some research has challenged this view. The objective of this study was to determine the influence of MDMA on subsequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8733831652e20a7e9e7a82894249f2a
https://doi.org/10.1016/j.ejphar.2012.12.024
https://doi.org/10.1016/j.ejphar.2012.12.024
Publikováno v:
Journal of Clinical Immunology. 32:106-113
CD1d presents glycolipid antigens such as α-galactosylceramide (αGalCer) to invariant natural killer T cells (iNKT). We have reported that activated iNKTs inhibit IL-10-producing autoreactive B cells, while promoting or leaving intact the normal B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0131c144dedb7b40dc34d1f667bf1e
https://doi.org/10.1007/s10875-011-9590-y
https://doi.org/10.1007/s10875-011-9590-y
Autor:
Madhu V. Midathada, Peter J. Kim, Nicholas P. Lang, Rangaswamy Govindarajan, Lawrence T. Kim, Luke Ratnasinghe, Eric R. Siegel, Randall J. Owens, Debra L. Simmons
Publikováno v:
Journal of Clinical Oncology. 25:1476-1481
Purpose Peroxisome proliferator-activated receptor gamma (PPARγ) mediates cell cycle arrest and adipocyte differentiation; has tumor suppressor activity in liposarcoma, lung, and prostate cancers; and suppresses colonic polyp formation in adenomatou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9112f9d6d4ea98c742df9dbeb7468d
https://doi.org/10.1200/jco.2006.07.2777
https://doi.org/10.1200/jco.2006.07.2777