Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Peter J. Jose"'
Autor:
Dolores M Conroy, Alison A Humbles, Sara M Rankin, Roger T Palframan, Paul D Collins, David A Griffiths-Johnson, Peter J Jose, Timothy J Williams
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 92, Pp 183-191 (1997)
Blood eosinophilia and tissue infiltration by eosinophils are frequently observed in allergic inflammation and parasitic infections. This selective accumulation of eosinophils suggested the existence of endogenous eosinophil-selective chemoattractant
Externí odkaz:
https://doaj.org/article/d426755c424140f5829a1315f0dc482c
Publikováno v:
Pediatric Asthma, Allergy & Immunology. 22:163-168
Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) patients both have chronic lung infection and neutrophilic inflammation, but there is a milder clinical phenotype in PCD. To understand the detailed inflammatory mechanisms in these two condit
Autor:
Maria-Jesus Sanz, Fernando B. Da Costa, Nilton S. Arakawa, Auro Nomizo, Peter J. Jose, Roberto Nicolete, Cristina Rius, Lúcia Helena Faccioli
Publikováno v:
Phytomedicine. 16:904-915
Budlein A has been reported to exert some analgesic and anti-inflammatory properties. In this study, we have evaluated its effect on LPS-induced leukocyte recruitment in vivo and the mechanisms involved in its anti-inflammatory activity. In vivo, int
Autor:
Andrew J. Tan, Peter J. Jose, Brian Leaker, Rachel C. Tennant, Andrew Bush, Edward M. Erin, Trevor T. Hansel, Peter J. Barnes, Gavin R. Jenkins, Onn Min Kon, Angela Zacharasiewicz, Helen Neighbour, Grant C. Nicholson
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 177:132-141
Rationale: Dithiothreitol (DTT) is commonly used to liquefy induced sputum samples before assessment of cytology, but causes reduction of disulfide bonds and denaturation of proteins.Objectives: To process sputum supernatants containing DTT to enable
Autor:
Rolf A.K. Stahl, Andrew C. Issekutz, Esteban J. Morcillo, Yafa Naim Abu Nabah, Amanda E. I. Proudfoot, Maria-Jesus Sanz, Peter J. Jose, Manuel de la Mata, Miguel Cerdá-Nicolás, Teresa Mateo, May Abu Taha, Julio Cortijo
Publikováno v:
ResearcherID
Angiotensin II (Ang-II) is associated with atherogenesis and arterial subendothelial mononuclear leukocyte infiltration. We have demonstrated that Ang-II causes the initial attachment of mononuclear cells to the arteriolar endothelium. We now report
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 171:814-822
Toll-like receptors 2 and 4 (TLR2, TLR4) enable cellular responses to bacterial lipoproteins, LPS, and endogenous mediators of cell damage. They have an established role in the activation of leukocytes, endothelial cells, and some smooth muscle cell
Autor:
Peter J. Jose, Mauro Perretti, Roderick J. Flower, Patrícia M.R. e Silva, Christianne Bandeira-Melo, Vinicius F. Carvalho, André Gustavo Bonavita, Bruno L. Diaz, Marco A. Martins
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 313:1416-1422
Previous investigations have provided evidence that the N-terminal peptide of annexin 1 (peptide Ac2-26) has the capacity of reproducing the anti-inflammatory actions of the full-length protein in many systems. In the current study, we report the eff
Autor:
Marc Conti, Dominique Henin, Peter J. Jose, Camille Taillé, Jorge Boczkowski, Jérôme Mégret, Michel Aubier, Christine Zedda, G. Martin, Abdelhamid Almolki
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 287:L26-L34
Heme oxygenase (HO), the heme-degrading enzyme, has shown anti-inflammatory effects in several models of pulmonary diseases. HO is induced in airways during asthma; however, its functional role is unclear. Therefore, we evaluated the role of HO on ai
Autor:
Antje Kirchem, Peter J. Jose, Fiona J. Culley, James E. Pease, Timothy J. Williams, Emma J Fadlon
Publikováno v:
European Journal of Immunology. 33:1302-1310
Chemokines play critical roles in governing the recruitment and activation of eosinophils at sites of allergic inflammation, particularly the asthmatic lung. However, we know little of how chemokine function is regulated post-translationally. Proteog
Autor:
Dorian O. Haskard, Sussan Nourshargh, Peter J. Jose, Timothy J. Williams, John P. Dangerfield, Karen Y. Larbi, Diane Marshall, Fiona J. Culley
Publikováno v:
Journal of Leukocyte Biology. 73:65-73
The study investigated the role of P-selectin in the responses of eosinophil transmigration and eotaxin generation in vivo elicited by interleukin (IL)-13, as compared with IL-4. Two murine models of leukocyte transmigration were used, migration into