Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Peter J. Jenks"'
Publikováno v:
Journal of Medical Microbiology. 68:188-196
Purpose Members of the ST127 uropathogenic E. coli (UPEC) clone have a high virulence potential and are also highly virulent in insect infection models. However, strains of this lineage are reported in relatively low numbers in many studies. ST127 st
Host Adaptation and Immune Modulation Are Mediated by Homologous Recombination inHelicobacter pylori
Publikováno v:
The Journal of Infectious Diseases. 191:579-587
Rearrangement of genomic DNA via homologous recombination provides an alternative mechanism of gene regulation that is essential for successful colonization of the gastric mucosa by Helicobacter pylori. Inoculation of outbred mice with the H. pylori
Publikováno v:
The Journal of Pathology. 201:596-602
The aims of this study were to determine whether colonization with Helicobacter felis resulted in the accumulation of mutations within murine gastric tissue and whether the degree of genetic damage was increased by p53 deficiency. Female C57BL/6 mice
Autor:
Paul Williams, David W. Ussery, Peter J. Jenks, Faye M. Barnard, Michael P. Messenger, Michael F. Loughlin, Hernan P. Fainberg
Publikováno v:
Molecular Microbiology. 51:15-32
Although successful and persistent colonization of the gastric mucosa depends on the ability to respond to changing environmental conditions and co-ordinate the expression of virulence factors during the course of infection, Helicobacter pylori posse
Autor:
Peter J Jenks, David I. Edwards
Publikováno v:
International Journal of Antimicrobial Agents. 19:1-7
Modern triple drug regimens are highly effective for treating Helicobacter pylori infection, but bacterial resistance to one of the most effective antibiotics, metronidazole, is a serious and increasing problem. The activity of metronidazole in H. py
Autor:
Richard L. Ferrero, Peter J. Jenks
The specificity of Helicobacter pylori for the human host is the consequence of a series of adaptations that probably occurred many thousands of years ago. This adaptation has provided H. pylori with an important advantage in vivo because unlike most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baa8a45e9f9caa86b909c418b30b33b7
https://doi.org/10.1128/9781555818005.ch46
https://doi.org/10.1128/9781555818005.ch46
Autor:
Peter J. Jenks
Publikováno v:
Journal of Medical Microbiology. 50:485-488
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:777-781
The Helicobacter pylori SS1 mouse model was used to characterize the development of resistance in H. pylori after treatment with metronidazole monotherapy and to examine the effect of prior exposure to metronidazole on the efficacy of a metronidazole
Autor:
Peter J. Jenks
Publikováno v:
BMJ. 317:1568-1571
Considerable advances in automated DNA sequencing and bioinformatics have made the sequencing of entire microbial genomes a reality (see fig 1). Researchers have been quick to recognise the scientific value of microbial sequence data, and there is no