Comparison of rosmarinic acid content in commercial tinctures produced from fresh and dried lemon balm (Melissa officinalis)

Autor: Alberto Sanchez-Medina, Christopher J. Etheridge, Geoffrey E. Hawkes, Peter J. Hylands, Barbara A. Pendry, Michael J. Hughes, Olivia Corcoran

Publikováno v: Journal of Pharmacy & Pharmaceutical Sciences, Vol 10, Iss 4 (2007)

Purpose. To measure the rosmarinic acid content of eight commercial tinctures derived from fresh (n= 5) and dried (n=3) Melissa officinalis herb. Methods. Rosmarinic acid and the internal standard (esculin) were purchased from Aldrich Chemical Co. Th

Externí odkaz: https://doaj.org/article/548d3f28803a473c8f3e6e6024b741fa

Proteomic landscape of TGF-β1-induced fibrogenesis in renal fibroblasts

Autor: Manuel Mayr, Mazhar Noor, Peter J. Hylands, Shujun Zhou, Xiaoke Yin, Qihe Xu

Publikováno v: Zhou, S, Yin, X, Mayr, M, Noor, M, Hylands, P & Xu, Q 2020, ' Proteomic landscape of TGF-β1-induced fibrogenesis in renal fibroblasts ', Scientific Reports, vol. 10, no. 1, 19054 . https://doi.org/10.1038/s41598-020-75989-4
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports

Transforming growth factor-β1 (TGF-β1) plays a premier role in fibrosis. To understand the molecular events underpinning TGF-β1-induced fibrogenesis, we examined the proteomic profiling of a TGF-β1-induced in vitro model of fibrosis in NRK-49F no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fefbed62da876c0669ff2139e1374e3
https://kclpure.kcl.ac.uk/ws/files/149532156/Proteomic_landscape_of_TGF_1_induced_XU_Publishedonline4November2020_GOLD_VoR_CC_BY_.pdf

Assessment ofPolygonum capitatumBuch.-Ham. ex D.Don by metabolomics based on gas chromatography with mass spectrometry

Autor: Cristina Legido-Quigley, Yong Huang, Pei Han, Peter J. Hylands

Publikováno v: Journal of Separation Science. 39:1979-1986

Polygonum capitatum is widely used in southwest China. It has considerable therapeutic efficacy for urinary tract infections. P. capitatum contains multiple components and quality assessment can be achieved by means of metabolic fingerprinting. In th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcf1b919a23b870ab074640b4a234d40
https://doi.org/10.1002/jssc.201501331

The double mutation of cytochrome P450's and fatty acid desaturases affect lipid regulation and longevity in C. elegans

Autor: Stephen R. Stürzenbaum, Peter J. Hylands, Soudabeh Imanikia

Publikováno v: Biochemistry and Biophysics Reports

An imbalance between energy uptake and energy expenditure can lead to obesity and increase the risk of coronary heart disease, high blood pressure, stroke, type II diabetes and some cancers. Given that key elements of the energy pathway are evolution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221f622f40aa1279191398044052c5ef

Metabolic phenotyping in the mouse model of urinary tract infection shows that 3-hydroxybutyrate in plasma is associated with infection

Autor: Peter J. Hylands, Yaoyao Wang, Cristina Legido-Quigley, Pei Han, Yumin Xie, Wu Yang, Wenying Xiang, Yong Huang

Publikováno v: PLoS ONE
Han, P, Huang, Y, Xie, Y, Yang, W, Wang, Y, Xiang, W, Hylands, P J & Legido Quigley, C 2017, ' Metabolic phenotyping in the mouse model of urinary tract infection shows that 3-hydroxybutyrate in plasma is associated with infection ', PL o S One, vol. 12, no. 10, e0186497 . https://doi.org/10.1371/journal.pone.0186497
PLoS ONE, Vol 12, Iss 10, p e0186497 (2017)

Urinary tract infection is one of the most common bacterial infections worldwide. Current diagnosis of urinary tract infection chiefly relies on its clinical presentation, urine dipstick tests and urine culture. Small molecules found in bio-fluids re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9851ea3a8bb8b8a4812893191fca94e3
https://pubmed.ncbi.nlm.nih.gov/29036204