Zobrazeno 1 - 10 of 79 pro vyhledávání: '"Peter J. Hanson"'
1
IOT honeynet for military deception and indications and warnings
Autor: Lucas Truax, Peter J. Hanson, David D. Saranchak
Publikováno v: Autonomous Systems: Sensors, Vehicles, Security, and the Internet of Everything.
Honeyman, named for the American Revolutionary War spy and source of disinformation, is an IoT distributed deception platform (DDP), aka “honeynet”, based approach to military deception and indications and warning (I&W) generation. While DDP appr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e3a0623a3f5923b25bed68f91146054
https://doi.org/10.1117/12.2305071
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3
A novel concentration dependent amino acid ion pair strategy to mediate drug permeation using indomethacin as a model insoluble drug
Autor: Peter J. Hanson, Afzal-Ur-Rahman Mohammed, Amr ElShaer
Publikováno v: European Journal of Pharmaceutical Sciences. 62:124-131
Assessment of oral drug bioavailability is an important parameter for new chemical entities (NCEs) in drug development cycle. After evaluating the pharmacological response of these new molecules, the following critical stage is to investigate their i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7cf1bf1a27ed5c4278377e57ddd11a
https://doi.org/10.1016/j.ejps.2014.05.022
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4
Physicochemical characterisation, drug polymer dissolution and in vitro evaluation of phenacetin and phenylbutazone solid dispersions with polyethylene glycol 8000
Autor: Peter J. Hanson, Afzal-Ur-Rahman Mohammed, Sheraz Khan, Hannah Batchelor, Yvonne Perrie
Publikováno v: Journal of Pharmaceutical Sciences. 100:4281-4294
Poor water solubility leads to low dissolution rate and consequently, it can limit bioavailability. Solid dispersions, where the drug is dispersed into an inert, hydrophilic polymer matrix can enhance drug dissolution. Solid dispersions were prepared
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46ed90d981ee4bfbf94d549e255717b
https://doi.org/10.1002/jps.22613
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5
Genomic evaluation during permeability of indomethacin and its solid dispersion
Autor: Peter J. Hanson, Ayesha S. Rahman, Yvonne Perrie, Afzal-Ur-Rahman Mohammed, Sheraz Khan, Amr ElShaer
Publikováno v: Journal of Drug Targeting. 19:615-623
Drug resistance was first identified in cancer cells that express proteins known as multidrug resistance proteins that extrude the therapeutic agents out of the cells resulting in alteration of pharmacokinetics, tissue distribution, and pharmacodynam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883732775560a496ef6ba26895eb57a8
https://doi.org/10.3109/1061186x.2010.531730
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6
Paracellular permeability is increased by basal lipopolysaccharide in a primary culture of colonic epithelial cells; an effect prevented by an activator of Toll-like receptor-2
Autor: Peter J. Hanson, Anthony P. Moran, Kate Butler
Publikováno v: Innate Immunity. 17:269-282
Lipopolysaccharide (LPS), which generally activates Toll-like receptor 4 (TLR4), is expressed on commensal colonic bacteria. In a number of tissues, LPS can act directly on epithelial cells to increase paracellular permeability. Such an effect in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a38caf7fea183c0d3ffcc5c53d0e96f
https://doi.org/10.1177/1753425910367813
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7
Lipoplexes Formulation and Optimisation: In Vitro Transfection Studies Reveal No Correlation with In Vivo Vaccination Studies
Autor: Yvonne Perrie, Peter J. Hanson, Vincent W. Bramwell, Anil Vangala, Sarah E. McNeil
Publikováno v: Current Drug Delivery. 7:175-187
The aim of these studies was to compare the effect of liposome composition on physico-chemical characteristics and transfection efficacy of cationic liposomes both in vitro and in vivo. Comparison between 4 popularly used cationic lipids, showed 3b-N
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd8ba4d3465552e9fb18612f2fd1be8
https://doi.org/10.2174/156720110791011774
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8
High permeability of the anionic form restricts accumulation of indomethacin by cultured gastric surface epithelial cells exposed to low apical pH
Autor: Klairi M. Kavvada, Vanessa Moore, James G. Murray, Peter J. Hanson, Alan G. A. Coombes
Publikováno v: European Journal of Pharmacology. 549:41-49
The 'ion-trapping' hypothesis suggests that the intracellular concentration of acidic non-steroidal anti-inflammatory drugs in gastric epithelial cells could be much higher than in the gastric lumen, and that such accumulation could contribute to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c7b7ec1e9726a0c5cfd7407a025353
https://doi.org/10.1016/j.ejphar.2006.08.033
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9
Forecasting Annual Harvests of Atlantic and Gulf Menhaden
Autor: Douglas S. Vaughan, Sridhar Narayan, Peter J. Hanson
Publikováno v: North American Journal of Fisheries Management. 26:753-764
Continuous records of annual landings and fishing effort exist in the Atlantic purse-seine fishery for Atlantic menhaden Brevoortia tyrannus since 1940 and the Gulf of Mexico fishery for Gulf menhaden B. patronus since 1946. Currently, year-ahead for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::943b271d0e01818833636ee04ddd42f5
https://doi.org/10.1577/m04-096.1
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