Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Peter J. Felsburg"'
Autor:
Olivier Humbert, Frieda Chan, Yogendra S. Rajawat, Troy R. Torgerson, Christopher R. Burtner, Nicholas W. Hubbard, Daniel Humphrys, Zachary K. Norgaard, Patricia O'Donnell, Jennifer E. Adair, Grant D. Trobridge, Andrew M. Scharenberg, Peter J. Felsburg, David J. Rawlings, Hans-Peter Kiem
Publikováno v:
Blood Advances, Vol 2, Iss 9, Pp 987-999 (2018)
Abstract: Hematopoietic stem-cell gene therapy is a promising treatment of X-linked severe combined immunodeficiency disease (SCID-X1), but currently, it requires recipient conditioning, extensive cell manipulation, and sophisticated facilities. With
Externí odkaz:
https://doaj.org/article/3e55cf5967d441c1ad4a379d1df78d1a
Autor:
Peter J. Felsburg
Publikováno v:
Schalm's Veterinary Hematology. :431-435
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1199c3ac0979ecdc86d0ab38b88445be
https://doi.org/10.1002/9781119500537.ch54
https://doi.org/10.1002/9781119500537.ch54
Autor:
Richard Schlegel, Bennett Jenson, Joseph T. Newsome, Peter J. Felsburg, Hajo Delius, Tania Apolinario, Vanessa A. Olcese, Hang Yuan, Shin-je Ghim, Mary Beth Martin
Publikováno v:
Virology. 359:28-36
A novel canine papillomavirus, CfPV-2, was cloned from a footpad lesion of a golden retriever. Unlike the known canine oral papillomavirus (COPV), which has a double-stranded DNA genome size of 8607 bps, the genome of CfPV-2 is 8101 bps. Some of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b18997894b0190c846ed0ea68fd15f
https://doi.org/10.1016/j.virol.2006.08.029
https://doi.org/10.1016/j.virol.2006.08.029
Autor:
Suk See De Ravin, Harry L. Malech, Christopher R. Burtner, Hans Peter Kiem, Peter J. Felsburg, Brian P. Sorrentino
Publikováno v:
Human gene therapy. Clinical development. 26(1)
Since the occurrence of T cell leukemias in the original human γ-retroviral gene therapy trials for X-linked severe combined immunodeficiency (XSCID), considerable effort has been devoted to developing safer vectors. This review summarizes gene ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ca483b1e58612961eae0295b6c6940
https://pubmed.ncbi.nlm.nih.gov/25603151
https://pubmed.ncbi.nlm.nih.gov/25603151
Autor:
Harry L. Malech, Brian J. Hartnett, Nora Naumann, Peter F Moore, William Vernau, Douglas R. Kennedy, Peter J. Felsburg, Uimook Choi, Gilda F. Linton, Suk See Ting-De Ravin, Jeffrey S. Kennedy, Narda L. Whiting-Theobald
Publikováno v:
Blood. 107:3091-3097
X-linked severe combined immunodeficiency (XSCID) is characterized by profound immunodeficiency and early mortality, the only potential cure being hematopoietic stem cell (HSC) transplantation or gene therapy. Current clinical gene therapy protocols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7917e168dfa3b6d63a0698b59d36dc6
https://doi.org/10.1182/blood-2005-10-4057
https://doi.org/10.1182/blood-2005-10-4057
Publikováno v:
American Journal of Veterinary Research. 63:358-362
Objective–To investigate the potential cell-mediated immune response of atopic dogs to the yeastMalassezia pachydermatisand to correlate it with the type-1 hypersensitivity (humoral) response of the same population of dogs.Animals–16 clinically n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cef4b66f087522a1c822986868988b1
https://doi.org/10.2460/ajvr.2002.63.358
https://doi.org/10.2460/ajvr.2002.63.358
Autor:
Hang Yuan, Peter J. Felsburg, Jennifer A. Luff, Peter F Moore, Richard Schlegel, Douglas R. Kennedy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e102033 (2014)
PLoS ONE, Vol 9, Iss 7, p e102033 (2014)
X-linked severe combined immunodeficiency (XSCID) is caused by a genetic mutation within the common gamma chain (γc), an essential component of the cytokine receptors for interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21. XSCID patients are mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7c55b9006d98f202460433136619a6
http://europepmc.org/articles/PMC4099134
http://europepmc.org/articles/PMC4099134
Autor:
Jennifer E. Adair, Christopher R. Burtner, David J. Rawlings, Brian C. Beard, Douglas R. Kennedy, Peter J. Felsburg, Andrew M. Scharenberg, Hans-Peter Kiem, Martin E. Wohlfahrt, Troy R. Torgerson, Grant D. Trobridge
Publikováno v:
Blood. 123(23)
Current approaches to hematopoietic stem cell (HSC) gene therapy involve the collection and ex vivo manipulation of HSCs, a process associated with loss of stem cell multipotency and engraftment potential. An alternative approach for correcting blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bddbe2950344847dc05aaee8a9e99b3
https://pubmed.ncbi.nlm.nih.gov/24642749
https://pubmed.ncbi.nlm.nih.gov/24642749
Autor:
Grant D. Trobridge, Peter J. Felsburg, Andrew M. Scharenberg, Olivier Humbert, Frieda Chan, Patricia O'Donnell, Daniel Humphrys, David J. Rawlings, Jennifer E. Adair, Hans-Peter Kiem, Nicholas Hubbard, Troy R. Torgerson
Publikováno v:
Blood. 128:1348-1348
In both humans and canines, X-linked severe combined immunodeficiency disease (XSCID) is caused by mutations in the interleukin-2 receptor gamma chain gene (IL2RG) which results in a lack of response to common gamma-chain (gammaC) dependent cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2efc44e4623a932090a038b0a8cffe99
https://doi.org/10.1182/blood.v128.22.1348.1348
https://doi.org/10.1182/blood.v128.22.1348.1348
Publikováno v:
Thrombosis and Haemostasis. 103:475-477
A mutation in the canine Kindlin-3 geneassociated with increased bleeding risk and susceptibility to infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8495b83a0e0f1b03ff899fc6694d7181
https://doi.org/10.1160/th09-09-0571
https://doi.org/10.1160/th09-09-0571