Zobrazeno 1 - 10
of 446
pro vyhledávání: '"Peter J. Dyck"'
Autor:
David Adams, Ole B. Suhr, Peter J. Dyck, William J. Litchy, Raina G. Leahy, Jihong Chen, Jared Gollob, Teresa Coelho
Publikováno v:
BMC Neurology, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Patisiran is an investigational RNA interference (RNAi) therapeutic in development for the treatment of hereditary ATTR (hATTR) amyloidosis, a progressive disease associated with significant disability, morbidity, and mortality. M
Externí odkaz:
https://doaj.org/article/af4683532dd9463a8cea7c211ead29bc
Autor:
Pannathat Soontrapa, Peter J. Dyck, P. James B. Dyck, Caroline M. Klein, JaNean Engelstad, Jenny Davies, Shelly Shahar, W. Scott Harmsen, Jay Mandrekar, Robert J. Spinner, Cristiane M. Ida, Christopher J. Klein
Publikováno v:
Journal of the Peripheral Nervous System.
Autor:
Jenny L. Davies, Karen A. Lodermeier, Diane M. Klein, Rickey E. Carter, P. James B. Dyck, William J. Litchy, Peter J. Dyck
Publikováno v:
Muscle & Nerve.
Autor:
Marcus V. Pinto, Peng‐Soon Ng, Ruple S. Laughlin, Prabin Thapa, Catarina Aragon Pinto, Shahar Shelly, Kamal Shouman, Peter J. Dyck, P. James B. Dyck
Publikováno v:
Muscle Nerve
Recently, our group found an association between diabetes mellitus (DM) and lumbosacral radiculoplexus neuropathy (LRPN) in Olmsted County, Minnesota; we found a higher risk (odds ratio [OR], 7.91) for developing LRPN in diabetic compared with nondia
Autor:
Kamal Shouman, Michelle L. Mauermann, Robert J. Spinner, Benjamin M. Howe, JaNean Engelstad, Peter J. Dyck, Grayson Beecher, Bruce V. Taylor, Christopher J. Klein, Shahar Shelly, John Mills, Divyanshu Dubey, Elie Naddaf, P. James B. Dyck, Sarah E. Berini, Jennifer M. Martinez-Thompson
Publikováno v:
Neurology. 97:e1392-e1403
Background and ObjectivesTo longitudinally investigate patients with multifocal acquired demyelinating sensory and motor neuropathy (MADSAM), quantifying timing and location of sensory involvements in motor onset patients, along with clinicohistopath
Autor:
Kimberly K. Amrami, Peter J. Dyck, Divyanshu Dubey, Kamal Shouman, Rocio Vazquez Do Campo, Ja Nean K. Engelstad, Shahar Shelly, Robert J. Spinner, P. James B. Dyck, Pritikanta Paul, Christopher J. Klein
Publikováno v:
Neurology. 96:e2078-e2089
ObjectiveSensory loss with normal nerve conduction studies (NCS) from focal sensory root inflammatory demyelination is characteristic of chronic immune sensory polyradiculopathy (CISP). However, nonpure cases involving motor and distal sensory nerves
Autor:
P. James B. Dyck, Benjamin M. Howe, Prabin Thapa, Peter J. Dyck, Marcus V. Pinto, Ruple S. Laughlin, Peng Soon Ng
Publikováno v:
Neurology
ObjectiveTo determine whether patients in the community with lumbosacral radiculoplexus neuropathy (LRPN) have milder neuropathy than referral patients, we characterized the outcomes and survival of population-based compared to referral-based LRPN co
Autor:
Shiangtung W. Jung, Li Jung Tai, Márcia Waddington-Cruz, William J. Litchy, Sotirios Tsimikas, Peter J. Dyck, Cecilia Monteiro, Gustavo Buchele, Julian D. Gillmore, Michela Brambatti, John L. Berk, Eugene Schneider, Yukio Ando, Teresa Coelho, Morie A. Gertz, Merrill D. Benson, Nicholas J. Viney, Louis O'Dea, Richard S. Geary, Brett P. Monia, Sami Khella, Laura Obici
Publikováno v:
Neurology and therapy, vol 10, iss 1
Neurology and Therapy
Neurology and Therapy
Introduction AKCEA-TTR-LRx is a ligand-conjugated antisense (LICA) drug in development for the treatment of hereditary transthyretin amyloidosis (hATTR), a fatal disease caused by mutations in the transthyretin (TTR) gene. AKCEA-TTR-LRx shares the sa
Autor:
Brian A. Crum, Kimberly K. Amrami, P. James B. Dyck, Matthew C. Kiernan, Robert J. Spinner, Michelle L. Mauermann, Bruce V. Taylor, Jennifer A. Tracy, Peter J. Dyck
Publikováno v:
Journal of Clinical Neuromuscular Disease. 22:1-10
Objectives The objective of the study is to distinguish the mechanisms of disease for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal motor neuropathy (MMN), which we believe to be fundamentally different. However, dis
Autor:
Janice F. Wiesman, Michael Polydefkis, William J. Litchy, Michelle L. Mauermann, P. James B. Dyck, Shiangtung W. Jung, Brenda F. Baker, Michael L. Pollock, Spencer D. Guthrie, John C. Kincaid, Peter J. Dyck, Elizabeth J. Ackermann
Publikováno v:
Muscle & Nerve
Introduction Inotersen, an antisense oligonucleotide inhibitor of transthyretin (TTR) protein production, demonstrated significant benefit versus placebo in the modified Neuropathy Impairment Score (NIS) +7 neurophysiologic tests (mNIS+7) in patients