Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter J. Blanco Carcache"'
Autor:
Peter J. Blanco Carcache, Ines Y. Castro-Dionicio, Nathan P. Mirtallo Ezzone, Eric D. Salinas-Arrellano, Joshua Bahar, Steven K. Clinton, A. Douglas Kinghorn
Publikováno v:
Molecules, Vol 29, Iss 20, p 4919 (2024)
Currently, clinically available cancer chemopreventive drug options are limited to mostly tamoxifen and its derivatives, such as raloxifene, and approved specifically for breast cancer. Thus, the availability of chemopreventive drug molecules for oth
Externí odkaz:
https://doaj.org/article/8fc3ad2a6b26454587d1fd5af3bf42b2
Autor:
Peter J. Blanco Carcache, Gerardo D. Anaya Eugenio, Tran Ngoc Ninh, Curtis E. Moore, José Rivera-Chávez, Yulin Ren, Djaja D. Soejarto, A. Douglas Kinghorn
Publikováno v:
SSRN Electronic Journal.
Compounds derived from natural sources have been major contributors to the area of cancer chemotherapy for decades. As part of an ongoing effort to discover anticancer drug leads from tropical plants, a large-scale collection of Glycosmis ovoidea Pie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99d59d5395cd2994e55a8b2b3bceba9
https://doi.org/10.2139/ssrn.4147476
https://doi.org/10.2139/ssrn.4147476
Autor:
Hui Li, Peixuan Guo, Sijin Guo, Peter J. Blanco Carcache, Congcong Xu, Wah Chiu, Kaiming Zhang
Publikováno v:
RNA (New York, N.Y.). 27(9)
In biological systems, conformational changes and allosteric modulation play pivotal roles in regulating biological functions, such as the dynamic change of protein molecules, in response to binding or interacting with other factors such as pH, volta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a35c0142d293d42fb064cc4564bc01
https://pubmed.ncbi.nlm.nih.gov/34193550
https://pubmed.ncbi.nlm.nih.gov/34193550
Publikováno v:
Sustainable Development and Biodiversity ISBN: 9783030747787
There are five major structural groups of cancer chemotherapeutic agents derived from higher plants approved clinically in the USA. These are used either in their unmodified naturally occurring form, as semi-synthetic derivatives, or as a conjugate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dc12e0e711687509ee0b17369c244b3
https://doi.org/10.1007/978-3-030-74779-4_17
https://doi.org/10.1007/978-3-030-74779-4_17
Autor:
Djaja D. Soejarto, A. Douglas Kinghorn, Yulin Ren, Tran Ngoc Ninh, Peter J. Blanco Carcache, Gerardo D. Anaya-Eugenio
Publikováno v:
Phytother Res
The rare flavone 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone (PMF) has been isolated from several plant species, and its cytotoxic activity has been reported against many types of cancer cells. In this study, PMF was purified from Glycomis ovoidea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743327ec8344ce0f4de6b9b668a028a2
https://pubmed.ncbi.nlm.nih.gov/33124130
https://pubmed.ncbi.nlm.nih.gov/33124130
Publikováno v:
Food Chemistry. 202:269-275
The bioassay-guided fractionation of the aril of M. fragrans (mace spice) yielded five phenolic compounds, one new acyclic bis phenylpropanoid (1) and four previously known phenolic compounds: compounds (1) (S) 1-(3, 4, 5-trimethoxyphenyl)-2-(3-metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f58900d402940b112f561fcb6a70c10
https://doi.org/10.1016/j.foodchem.2016.01.060
https://doi.org/10.1016/j.foodchem.2016.01.060
Publikováno v:
Biotechnol Adv
Higher plant constituents have afforded clinically available anticancer drugs. These include both chemically unmodified small molecules and their synthetic derivatives currently used or those in clinical trials as antineoplastic agents, and an update
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded42355411ce1e53f504879c114d4cc
https://pubmed.ncbi.nlm.nih.gov/30633954
https://pubmed.ncbi.nlm.nih.gov/30633954