Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Peter J. Binns"'
Autor:
Robin J. Nakkula, Youngjoo Byun, Werner Tjarks, Lai Chu Wu, Kent J. Riley, Rolf F. Barth, Peter J. Binns, Weilian Yang
Publikováno v:
Applied Radiation and Isotopes. 106:251-255
In this report we describe studies with N5-2OH, a carboranyl thymidine analog (CTA), which is a substrate for thymidine kinase 1 (TK1), using the F98 rat glioma model. In vivo BNCT studies have demonstrated that intracerebral (i.c.) osmotic pump infu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ae5e4c366022255c8965d6d20c5f6d
https://doi.org/10.1016/j.apradiso.2015.06.031
https://doi.org/10.1016/j.apradiso.2015.06.031
Autor:
Owendi Ongayi, Kent J. Riley, Tianyao Huo, Weilian Yang, Vijay Gottumukkala, Shinji Kawabata, Rolf F. Barth, Peter J. Binns, Gong Wu, M. Graça H. Vicente
Publikováno v:
Journal of Neuro-Oncology. 103:175-185
Boron neutron capture therapy (BNCT) is based on the nuclear capture and fission reactions that occur when non-radioactive 10B is irradiated with low energy thermal neutrons to produce α-particles (10B[n,α]7Li). Carboranylporphyrins are a class of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f4892e1a73db3236bd4379227b9e69
https://doi.org/10.1007/s11060-010-0376-5
https://doi.org/10.1007/s11060-010-0376-5
Autor:
Peter J. Binns, Sanath Kumar, Bijan Sedghi, Michael C. Joiner, Svend O. Freytag, Stephen L. Brown, Kenneth N. Barton, Jay Burmeister, Benjamin Movsas, Jae Ho Kim
Publikováno v:
Journal of Radiation Research. 51:621-626
Boron neutron capture therapy/BNCT/Adenoviral gene therapy/Sodium iodide symporter/NIS. Boron Neutron Capture Therapy (BNCT) effectiveness depends on the preferential sequestration of bor on in cancer cells relative to normal tissue cells. We present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbbaf99763a65d5b3fee49fa7b66b3e
https://doi.org/10.1269/jrr.10036
https://doi.org/10.1269/jrr.10036
Publikováno v:
Applied Radiation and Isotopes. 67:S328-S331
In the present report we have summarized studies carried out over the past five years on molecular targeting of the epidermal growth factor receptor (EGFR) and its mutant isoform, EFGRvIII, for BNCT of genetically engineered F98 rat gliomas, expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7770a3200f80d35546d4bb44bcc6b48
https://doi.org/10.1016/j.apradiso.2009.03.030
https://doi.org/10.1016/j.apradiso.2009.03.030
Autor:
V.A. Nievaart, W. S. Kiger, Kent J. Riley, R.L. Moss, K. Sköld, Iiro Auterinen, Otto K. Harling, Tiina Seppälä, L. Viererbl, M. Marek, J.R. Albritton, A. Rezaei, Peter J. Binns, Sauli Savolainen
Publikováno v:
Medical Physics. 35:5419-5425
The meaningful sharing and combining of clinical results from different centers in the world performing boronneutron capture therapy (BNCT) requires improved precision in dose specification between programs. To this end absorbed dose normalizations w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d799cb479ada24d965994e86946e7012
https://doi.org/10.1118/1.3005480
https://doi.org/10.1118/1.3005480
Autor:
Weilian Yang, Melvin L. Moeschberger, Sureshbabu Narayanasamy, Gong Wu, Staffan Eriksson, Michele Swindall, Youngjoo Byun, Kent J. Riley, Kevin P. Tordoff, Werner Tjarks, Peter J. Binns, Rolf F. Barth
Publikováno v:
Proceedings of the National Academy of Sciences. 105:17493-17497
The purpose of the present study was to evaluate the effectiveness of a 3-carboranyl thymidine analogue (3CTA), 3-[5-{2-(2,3-dihydroxyprop-1-yl)- o -carboran-1-yl}pentan-1-yl] thymidine, designated N5–2OH, for boron neutron capture therapy (BNCT) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d5f24b4412a097d1565f1564a2cbc0
https://doi.org/10.1073/pnas.0809569105
https://doi.org/10.1073/pnas.0809569105
Autor:
W. S. Kiger, Peter J. Binns, Mariana Casal, Kent J. Riley, Otto K. Harling, Herman Blaumann, S. J. González, O. A. Calzetta Larrieu, Juan Longhino
Publikováno v:
Medical Physics. 35:1295-1298
A dosimetry intercomparison between the boron neutron capture therapy groups of the Massachusetts Institute of Technology (MIT) and the Comisión Nacional de Energía Atómica (CNEA), Argentina was performed to enable combined analyses of NCT patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018af7ac2a3f47289f8e1d1b3215f72d
https://doi.org/10.1118/1.2884856
https://doi.org/10.1118/1.2884856
Publikováno v:
Radiation Protection Dosimetry. 126:610-614
Normalisation of prescribed dose in boron neutron capture therapy (BNCT) is needed to facilitate combining clinical data from different centres in the world to help expedite development of the modality. The approach being pursued within the BNCT comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a0968345797bbf55256cd7305e2546
https://doi.org/10.1093/rpd/ncm124
https://doi.org/10.1093/rpd/ncm124
Autor:
Kent J. Riley, Arlin B. Rogers, Jeffrey A. Coderre, Kathleen S. Cormier, Richard L. Julius, M. Frederick Hawthorne, Bradley W. Schuller, Peter J. Binns
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 68:205-210
Purpose: This report addresses the incidence of vascular endothelial cell apoptosis in the mouse small intestine in relation to the radiation-induced gastrointestinal (GI) syndrome. Methods and Materials: Nonanesthetized mice received whole-body irra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2be8cea71c56e36ee97b3b98854c93af
https://doi.org/10.1016/j.ijrobp.2006.12.069
https://doi.org/10.1016/j.ijrobp.2006.12.069
Improved Dose Targeting for a Clinical Epithermal Neutron Capture Beam Using Optional 6Li Filtration
Autor:
Wei Gao, Kent J. Riley, Otto K. Harling, Yakov Ostrovsky, J. Raymond Albritton, W. S. Kiger, Peter J. Binns
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 67:1484-1491
Purpose: The aim of this study was to construct a 6 Li filter and to improve penetration of thermal neutrons produced by the fission converter–based epithermal neutron beam (FCB) for brain irradiation during boron neutron capture therapy (BNCT). Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7907368dc8f61aa65b10673fbb9a319
https://doi.org/10.1016/j.ijrobp.2006.11.022
https://doi.org/10.1016/j.ijrobp.2006.11.022