Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Peter J. Caspers"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 304 (2024)
We have developed a method to determine the limit of detection (LoD) for quantitative measurement of exogenous analytes in the outer layer of the human skin by in vivo confocal Raman spectroscopy. The method is in accordance with the guidelines of th
Externí odkaz:
https://doaj.org/article/5c3a431fcaf941428f27099bfe36a4e9
Autor:
Yassine Aaboubout, Quincy M. van der Toom, Maria A. J. de Ridder, Maria J. De Herdt, Berdine van der Steen, Cornelia G. F. van Lanschot, Elisa M. Barroso, Maria R. Nunes Soares, Ivo ten Hove, Hetty Mast, Roeland W. H. Smits, Aniel Sewnaik, Dominiek A. Monserez, Stijn Keereweer, Peter J. Caspers, Robert J. Baatenburg de Jong, Tom C. Bakker Schut, Gerwin J. Puppels, José A. Hardillo, Senada Koljenović
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveThe depth of invasion (DOI) is considered an independent risk factor for occult lymph node metastasis in oral cavity squamous cell carcinoma (OCSCC). It is used to decide whether an elective neck dissection (END) is indicated in the case of
Externí odkaz:
https://doaj.org/article/747aa41bb148456e9bc6861b26397bd8
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 542 (2021)
The composition of topical and transdermal formulations is known to determine the rate and the extent of drug delivery to and through the skin. However, to date, the role of excipients in these formulations on skin delivery of actives has received li
Externí odkaz:
https://doaj.org/article/f866b4957ce24cc196e41f830f0e66ce
Autor:
Hamed Abbasi, Lorraine J. Lauwerends, Tom C. Bakker Schut, Inês P. Santos, Peter J. Caspers, Jose A. U. Hardillo, Senada Koljenović, Alexander L. Vahrmeijer, Robert J. Baatenburg de Jong, Stijn Keereweer, Gerwin J. Puppels
Publikováno v:
Analyst, 148(12), 2647-2872. Royal Society of Chemistry
The analyst
The analyst
Near-infrared (NIR) fluorescence imaging using exogenous fluorescent agents provides whole-field images in real-time to assist the surgeon in the excision of a tumor. Although the method has high sensitivity, the specificity can sometimes be lower th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f6977840680e2c77a334b15e775f9a
https://pure.eur.nl/en/publications/bfb93ffc-5e3c-4e3c-92f1-cddedbb2544d
https://pure.eur.nl/en/publications/bfb93ffc-5e3c-4e3c-92f1-cddedbb2544d
Autor:
Lluis M. Mir, Gerwin J. Puppels, Caroline Robert, Angelo Paci, Alexander M.M. Eggermont, Emilie Lanoy, Matthieu Texier, Vincent Noordhoek Hegt, Senada Koljenović, Gorana Tomasic, Nyam Kamsu Kom, Atmane Seck, David Planchard, Benjamin Besse, Emilie Routier, Christine Mateus, Céline Boutros, Séverine Roy, Tom C. Bakker Schut, Peter J. Caspers, Antoine Azan
Mean LD score for the validation data set for Stratum Corneum skin layer for MEK inhibitors (A), EGFR inhibitors (B) and BRAF inhibitors (C) and for Viable Epidermis skin layer for MEK inhibitors (D), EGFR inhibitors (E) and BRAF inhibitors (F). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ecd191e71b2feda7c9ec688f3b0137b
https://doi.org/10.1158/0008-5472.22415429.v1
https://doi.org/10.1158/0008-5472.22415429.v1
Autor:
Lluis M. Mir, Gerwin J. Puppels, Caroline Robert, Angelo Paci, Alexander M.M. Eggermont, Emilie Lanoy, Matthieu Texier, Vincent Noordhoek Hegt, Senada Koljenović, Gorana Tomasic, Nyam Kamsu Kom, Atmane Seck, David Planchard, Benjamin Besse, Emilie Routier, Christine Mateus, Céline Boutros, Séverine Roy, Tom C. Bakker Schut, Peter J. Caspers, Antoine Azan
Summary of cutaneous adverse events at the different time point for each patient included in this study. n/a: not available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d3d084213de11c179b2a6167ee2d1d
https://doi.org/10.1158/0008-5472.22415420.v1
https://doi.org/10.1158/0008-5472.22415420.v1
Autor:
Lluis M. Mir, Gerwin J. Puppels, Caroline Robert, Angelo Paci, Alexander M.M. Eggermont, Emilie Lanoy, Matthieu Texier, Vincent Noordhoek Hegt, Senada Koljenović, Gorana Tomasic, Nyam Kamsu Kom, Atmane Seck, David Planchard, Benjamin Besse, Emilie Routier, Christine Mateus, Céline Boutros, Séverine Roy, Tom C. Bakker Schut, Peter J. Caspers, Antoine Azan
Revised Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480ca7e33c5a8a2e90e9f1d8c477383f
https://doi.org/10.1158/0008-5472.22415426.v1
https://doi.org/10.1158/0008-5472.22415426.v1
Autor:
Lluis M. Mir, Gerwin J. Puppels, Caroline Robert, Angelo Paci, Alexander M.M. Eggermont, Emilie Lanoy, Matthieu Texier, Vincent Noordhoek Hegt, Senada Koljenović, Gorana Tomasic, Nyam Kamsu Kom, Atmane Seck, David Planchard, Benjamin Besse, Emilie Routier, Christine Mateus, Céline Boutros, Séverine Roy, Tom C. Bakker Schut, Peter J. Caspers, Antoine Azan
Raman spectroscopy is a noninvasive and label-free optical technique that provides detailed information about the molecular composition of a sample. In this study, we evaluated the potential of Raman spectroscopy to predict skin toxicity due to tyros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d841ca02b5256f3888f01c11d96a097
https://doi.org/10.1158/0008-5472.c.6509285.v1
https://doi.org/10.1158/0008-5472.c.6509285.v1
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 887 (2020)
Previously, we reported the use of Confocal Raman Spectroscopy (CRS) to investigate the topical delivery of actives and excipients. We have also correlated the results from CRS with findings from in vitro diffusion studies in human skin. However, unt
Externí odkaz:
https://doaj.org/article/98ac06e7fe114fbe9fa856fe4af2c936
Autor:
Yassine Aaboubout, Viacheslav Artyushenko, Iskander Usenov, T. C. Bakker Schut, Elisa M. Barroso, L. C. van der Sar, Gerwin J. Puppels, Peter J. Caspers, Senada Koljenović, Alexey Bocharnikov, J.J. van den Dobbelsteen, M. R. Nunes Soares
Publikováno v:
Medical Engineering & Physics, 97, 40-46. Elsevier
Medical Engineering & Physics, 97
Medical Engineering & Physics, 97
This study reports on the effects of insertion velocity, needle tip geometry and needle diameter on tissue deformation and maximum insertion force. Moreover, the effect of multiple insertions with the same needle on the maximum insertion force is rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd4a90b74134bb07da6e04c81bed3a3
https://doi.org/10.1016/j.medengphy.2021.10.003
https://doi.org/10.1016/j.medengphy.2021.10.003