Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Peter J Wettstein"'
Autor:
Brett D Shepard, Davide De Forni, David R McNamara, Andrea Foli, Stacey A Rizza, Roshini S Abraham, Keith Knutson, Peter J Wettstein, Franco Lori, Andrew D Badley
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3096 (2008)
During uncontrolled HIV disease, both TNF-related apoptosis inducing ligand (TRAIL) and TRAIL receptor expression are increased. Enhanced TRAIL sensitivity is due to TRAIL receptor up-regulation induced by gp120. As a result of successful antiretrovi
Externí odkaz:
https://doaj.org/article/7c716647a9ab4942bd2923f33ba0cdf0
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-17 (2018)
Abstract Background Genetic introgression between divergent lineages is now considered more common than previously appreciated, with potentially important consequences for adaptation and speciation. Introgression is often asymmetric between populatio
Externí odkaz:
https://doaj.org/article/de1170aa023b40f3a0a23942b7efa2d3
Autor:
Kimberly G. Laffey, Robert J. Stiles, Melissa J. Ludescher, Tessa R. Davis, Shariq S. Khwaja, Richard J. Bram, Peter J. Wettstein, Venkataraman Ramachandran, Christopher A. Parks, Edwin E. Reyes, Alejandro Ferrer, Jenna M. Canfield, Cory E. Johnson, Richard D. Hammer, Diana Gil, Adam G. Schrum
Publikováno v:
Proceedings of the National Academy of Sciences. 119
During normal T cell development in mouse and human, a low-frequency population of immature CD4−CD8−double-negative (DN) thymocytes expresses early, mature αβ T cell antigen receptor (TCR). We report that these early αβ TCR+ DN (EADN) cells a
Autor:
Tessa R. Davis, Aaron J. Johnson, Jamie Rossjohn, Mark A. Daniels, Alejandro Ferrer, Adam G. Schrum, Deanne Hebrink, Kevin D. Pavelko, Stephen E. P. Smith, Jenna M. Canfield, Katelynn M. Wilton, Peter J. Wettstein, Dietmar J. Kappes, Diana Gil, Larry R. Pease, Scott R. Burrows, James McCluskey, April M. Huseby Kelcher, Claudia Neuhauser, Zhenjun Chen, Steven C. Neier, Eva M. Carmona, Andrew H. Limper, Robert J. Stiles
Publikováno v:
Sci Immunol
During αβ T cell development, T cell antigen receptor (TCR) engagement transduces biochemical signals through a protein-protein interaction (PPI) network that dictates dichotomous cell fate decisions. It remains unclear how signal specificity is co
Autor:
Eric L. Matteson, Cynthia S. Crowson, Michael A. Strausbauch, John M. Davis, Sherine E. Gabriel, Peter J. Wettstein, Keith L. Knutson, Sara J. Achenbach, Terry M. Therneau
Publikováno v:
Clin Immunol
To identify associations between immunostimulated cytokine production and disease characteristics, peripheral blood lymphocytes were collected from 155 adult patients with rheumatoid arthritis (RA) before and after a 5-year interval. The lymphocytes
Autor:
Chi-Ren Shyu, Tessa R. Davis, Venkataraman Ramachandran, Adam G. Schrum, Richard J. Bram, Kimberly G. Laffey, Diana Gil, Cory E. Johnson, Peter J. Wettstein, Richard D. Hammer, Melissa Ludescher, Shariq S. Khwaja, Robert J. Stiles
Publikováno v:
Blood. 134:1463-1463
T cell lymphoblastic leukemia (T-ALL) is an aggressive cancer arising from transformed thymocytes. Most human T-ALL involves hyperactive NOTCH signaling that is often caused by activating NOTCH mutations. However, the identification of specific molec
Publikováno v:
BMC Evolutionary Biology
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-17 (2018)
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-17 (2018)
Background Genetic introgression between divergent lineages is now considered more common than previously appreciated, with potentially important consequences for adaptation and speciation. Introgression is often asymmetric between populations and pa
Autor:
Pam Skaran, Myung S. Park, Jeff A. Sloan, Philip A. Low, David M. Sletten, Juliane Bingener, Peter J. Wettstein, Andrea L. McConico, Paul J. Novotny
Publikováno v:
Journal of the American College of Surgeons. 221:111-121
Background The Institute of Medicine has included the comparison of minimally invasive surgical techniques in its research agenda. This study seeks to evaluate a model for the comparison of minimally invasive procedures using patient-reported outcome
Publikováno v:
Journal of Immunological Methods. 412:24-34
T lymphocyte responses to challenges with multiple pathogens depend on the diversity of their T cell receptors (TcRs) that are heteroduplexes of alpha and beta chains. The regions of alpha and beta chains that define TcR specificity are encoded by re
Autor:
Zelalem Temesgen, Amy M. Sainski, Andrew D. Badley, Peter J. Wettstein, Giota Touloumi, Nathan W. Cummins, Jacqueline Neuhaus, James D. Neaton, Matthew S. Freiberg, Sharon R Lewin, Montserrat Plana, Michael A. Strausbauch, Stacey A. Rizza
Publikováno v:
AIDS Research and Human Retroviruses. 30:476-479
Most patients on suppressive antiretroviral therapy (ART) experience improvements in CD4 T cell count. However, some patients with undetectable viral load continue to lose CD4 T cells for unknown reasons. Casp8p41 is a host-derived protein fragment t