Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Peter J Stogios"'
Autor:
Malene L Urbanus, Andrew T Quaile, Peter J Stogios, Mariya Morar, Chitong Rao, Rosa Di Leo, Elena Evdokimova, Mandy Lam, Christina Oatway, Marianne E Cuff, Jerzy Osipiuk, Karolina Michalska, Boguslaw P Nocek, Mikko Taipale, Alexei Savchenko, Alexander W Ensminger
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 12, Pp 1-20 (2016)
Abstract Pathogens deliver complex arsenals of translocated effector proteins to host cells during infection, but the extent to which these proteins are regulated once inside the eukaryotic cell remains poorly defined. Among all bacterial pathogens,
Externí odkaz:
https://doaj.org/article/90c7ff684d7f4248a728c84036429cc9
An inserted α/β subdomain shapes the catalytic pocket of Lactobacillus johnsonii cinnamoyl esterase.
Autor:
Kin-Kwan Lai, Peter J Stogios, Clara Vu, Xiaohui Xu, Hong Cui, Sara Molloy, Alexei Savchenko, Alexander Yakunin, Claudio F Gonzalez
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23269 (2011)
Microbial enzymes produced in the gastrointestinal tract are primarily responsible for the release and biochemical transformation of absorbable bioactive monophenols. In the present work we described the crystal structure of LJ0536, a serine cinnamoy
Externí odkaz:
https://doaj.org/article/b8c3006b4f68446f94fa9a8f4093d465
Autor:
Emma Lash, Victoria Prudent, Peter J. Stogios, Alexei Savchenko, Suzanne M. Noble, Nicole Robbins, Leah E. Cowen
Publikováno v:
mBio. 14
Candida albicans is a leading human fungal pathogen that can cause life-threatening infections in immunocompromised individuals, with mortality rates of ~40%. The ability of this organism to grow in both yeast and filamentous forms is critical for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20e4217e74dfff570ae9bb26123e2b0f
https://doi.org/10.1128/mbio.03434-22
https://doi.org/10.1128/mbio.03434-22
Autor:
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J. Little, Tatiana Skarina, Peter J. Stogios, Sarah Birstonas, Brian K. Coombes, Alexei Savchenko
Publikováno v:
Infect Immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdc45b17e0588b3c7e6b377b50f1333
https://doi.org/10.1128/iai.00094-23
https://doi.org/10.1128/iai.00094-23
Autor:
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J. Little, Tatiana Skarina, Peter J. Stogios, Sarah Birstonas, Brian K. Coombes, Alexei Savchenko
Publikováno v:
Infect Immun
The NleGs are the largest family of type 3 secreted effectors in attaching and effacing (A/E) pathogens, such as enterohemorrhagic Escherichia coli (EHEC), enteropathogenic E. coli, and Citrobacter rodentium. NleG effectors contain a conserved C-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f0791c21853d442124e0dd36859481
https://doi.org/10.1128/iai.00505-22
https://doi.org/10.1128/iai.00505-22
Autor:
Jordan D. Lin, Peter J. Stogios, Kento T. Abe, Avril Wang, John MacPherson, Tatiana Skarina, Anne-Claude Gingras, Alexei Savchenko, Alexander W. Ensminger
Toxin-antitoxin (TA) systems are abundant genetic modules in bacterial chromosomes and on mobile elements. They are often patchily distributed and their physiological functions remain poorly understood. Here, we characterize a TA system inLegionella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1b8882417460f03b7f99a1306e8b752
https://doi.org/10.1101/2022.11.26.518041
https://doi.org/10.1101/2022.11.26.518041
Autor:
Melissa R. Cruz, Shane Cristy, Shantanu Guha, Giuseppe Buda De Cesare, Elena Evdokimova, Hiram Sanchez, Dominika Borek, Pedro Miramón, Junko Yano, Paul L. Fidel, Alexei Savchenko, David R. Andes, Peter J. Stogios, Michael C. Lorenz, Danielle A. Garsin
Publikováno v:
Nature Communications. 13
Fungal pathogens are a continuing challenge due to few effective antifungals and a rise in resistance. In previous work, we described the inhibition of Candida albicans virulence following exposure to the 68 amino acid bacteriocin, EntV, secreted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedb15cdb33ab3829e77703bbb4efdd2
https://doi.org/10.1038/s41467-022-33613-1
https://doi.org/10.1038/s41467-022-33613-1
Autor:
Patrick Diep, Peter J. Stogios, Elena Evdokimova, Alexei Savchenko, Radhakrishnan Mahadevan, Alexander F. Yakunin
Extracytoplasmic solute binding proteins (SBPs) are molecular shuttles involved in the cellular uptake of various small molecules and metal ions including Ni(II). Our previous study with the Ni(II) binding proteins (NiBPs) CjNikZ from Campylobacter j
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e903ea5ce2172339ec6281adda267e70
https://doi.org/10.1101/2022.10.03.510666
https://doi.org/10.1101/2022.10.03.510666
Autor:
Meenakshi Venkatesan, Michael Fruci, Lou Ann Verellen, Tatiana Skarina, Nathalie Mesa, Peter J. Stogios, Alexei Savchenko
The sulfonamides (sulfas) are the oldest class of synthetic antibacterial that target the essential, conserved dihydropteroate synthase (DHPS) enzyme, encoded by folP, through chemical mimicry of its substrate p-aminobenzoic acid (pABA). Resistance h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0da9c54d70b28e6130c75a1ff2f240ff
https://doi.org/10.1101/2022.06.30.498311
https://doi.org/10.1101/2022.06.30.498311
Autor:
Yilan Liu, Anna Khusnutdinova, Jinjin Chen, David Crisante, Khorcheska Batyrova, Kaushik Raj, Michelle Feigis, Erfan Shirzadi, Xiaotong Wang, Roham Dorakhan, Xue Wang, Peter J. Stogios, Alexander F. Yakunin, Edward H. Sargent, Radhakrishnan Mahadevan
Publikováno v:
Metabolic engineering. 74
Rising concerns about climate change and sustainable energy have attracted efforts towards developing environmentally friendly alternatives to fossil fuels. Biosynthesis of n-butane, a highly desirable petro-chemical, fuel additive and diluent in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2c333a312c97e5a690502847be175d
https://pubmed.ncbi.nlm.nih.gov/36244545
https://pubmed.ncbi.nlm.nih.gov/36244545