Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Peter J Rix"'
Autor:
James D Joseph, Beatrice Darimont, Wei Zhou, Alfonso Arrazate, Amy Young, Ellen Ingalla, Kimberly Walter, Robert A Blake, Jim Nonomiya, Zhengyu Guan, Lorna Kategaya, Steven P Govek, Andiliy G Lai, Mehmet Kahraman, Dan Brigham, John Sensintaffar, Nhin Lu, Gang Shao, Jing Qian, Kate Grillot, Michael Moon, Rene Prudente, Eric Bischoff, Kyoung-Jin Lee, Celine Bonnefous, Karensa L Douglas, Jackaline D Julien, Johnny Y Nagasawa, Anna Aparicio, Josh Kaufman, Benjamin Haley, Jennifer M Giltnane, Ingrid E Wertz, Mark R Lackner, Michelle A Nannini, Deepak Sampath, Luis Schwarz, Henry Charles Manning, Mohammed Noor Tantawy, Carlos L Arteaga, Richard A Heyman, Peter J Rix, Lori Friedman, Nicholas D Smith, Ciara Metcalfe, Jeffrey H Hager
Publikováno v:
eLife, Vol 8 (2019)
Externí odkaz:
https://doaj.org/article/d1935c5b03e6433ea06acf491e7dc6f2
Autor:
James D Joseph, Beatrice Darimont, Wei Zhou, Alfonso Arrazate, Amy Young, Ellen Ingalla, Kimberly Walter, Robert A Blake, Jim Nonomiya, Zhengyu Guan, Lorna Kategaya, Steven P Govek, Andiliy G Lai, Mehmet Kahraman, Dan Brigham, John Sensintaffar, Nhin Lu, Gang Shao, Jing Qian, Kate Grillot, Michael Moon, Rene Prudente, Eric Bischoff, Kyoung-Jin Lee, Celine Bonnefous, Karensa L Douglas, Jackaline D Julien, Johnny Y Nagasawa, Anna Aparicio, Josh Kaufman, Benjamin Haley, Jennifer M Giltnane, Ingrid E Wertz, Mark R Lackner, Michelle A Nannini, Deepak Sampath, Luis Schwarz, Henry Charles Manning, Mohammed Noor Tantawy, Carlos L Arteaga, Richard A Heyman, Peter J Rix, Lori Friedman, Nicholas D Smith, Ciara Metcalfe, Jeffrey H Hager
Publikováno v:
eLife, Vol 5 (2016)
ER-targeted therapeutics provide valuable treatment options for patients with ER+ breast cancer, however, current relapse and mortality rates emphasize the need for improved therapeutic strategies. The recent discovery of prevalent ESR1 mutations in
Externí odkaz:
https://doaj.org/article/e0d8a246d19143f9bd877f0b6caa0659
Autor:
Jeffrey H. Hager, Charles L. Sawyers, Michael E. Jung, Richard A. Heyman, Peter J. Rix, Ouathek Ouerfelli, Nian Wu, Elisa De Stanchina, Nicholas D. Smith, Mark Klang, Peter Smith-Jones, Howard I. Scher, Beatrice Darimont, Celine Bonnefous, Mark R. Herbert, Teresa Wasielewska, John Sensintaffar, Chunyan Cao, Guangbin Yang, Hong Zhao, Jing Qian, Gang Shao, Vivek Arora, Steven Dorow, Anna Aparicio, Ling Cai, Eric D. Bischoff, Kate Grillot, Yu Chen, Anna Dilhas, Samedy Ouk, Chris Tran, James D. Joseph, John Wongvipat, Nicola J. Clegg
PDF file - 185K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0f57c8b6ecb96bc53146deeb63d113
https://doi.org/10.1158/0008-5472.22393724.v1
https://doi.org/10.1158/0008-5472.22393724.v1
Autor:
Jeffrey H. Hager, Charles L. Sawyers, Michael E. Jung, Richard A. Heyman, Peter J. Rix, Ouathek Ouerfelli, Nian Wu, Elisa De Stanchina, Nicholas D. Smith, Mark Klang, Peter Smith-Jones, Howard I. Scher, Beatrice Darimont, Celine Bonnefous, Mark R. Herbert, Teresa Wasielewska, John Sensintaffar, Chunyan Cao, Guangbin Yang, Hong Zhao, Jing Qian, Gang Shao, Vivek Arora, Steven Dorow, Anna Aparicio, Ling Cai, Eric D. Bischoff, Kate Grillot, Yu Chen, Anna Dilhas, Samedy Ouk, Chris Tran, James D. Joseph, John Wongvipat, Nicola J. Clegg
PDF file - 181K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9d43c3d094fe2a4e4d08a204389238
https://doi.org/10.1158/0008-5472.22393718
https://doi.org/10.1158/0008-5472.22393718
Autor:
Jeffrey H. Hager, Charles L. Sawyers, Michael E. Jung, Richard A. Heyman, Peter J. Rix, Ouathek Ouerfelli, Nian Wu, Elisa De Stanchina, Nicholas D. Smith, Mark Klang, Peter Smith-Jones, Howard I. Scher, Beatrice Darimont, Celine Bonnefous, Mark R. Herbert, Teresa Wasielewska, John Sensintaffar, Chunyan Cao, Guangbin Yang, Hong Zhao, Jing Qian, Gang Shao, Vivek Arora, Steven Dorow, Anna Aparicio, Ling Cai, Eric D. Bischoff, Kate Grillot, Yu Chen, Anna Dilhas, Samedy Ouk, Chris Tran, James D. Joseph, John Wongvipat, Nicola J. Clegg
PDF file - 241K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95de4c884e1f7ad8e36b2ca14c471b7
https://doi.org/10.1158/0008-5472.22393730.v1
https://doi.org/10.1158/0008-5472.22393730.v1
Autor:
Jeffrey H. Hager, Charles L. Sawyers, Michael E. Jung, Richard A. Heyman, Peter J. Rix, Ouathek Ouerfelli, Nian Wu, Elisa De Stanchina, Nicholas D. Smith, Mark Klang, Peter Smith-Jones, Howard I. Scher, Beatrice Darimont, Celine Bonnefous, Mark R. Herbert, Teresa Wasielewska, John Sensintaffar, Chunyan Cao, Guangbin Yang, Hong Zhao, Jing Qian, Gang Shao, Vivek Arora, Steven Dorow, Anna Aparicio, Ling Cai, Eric D. Bischoff, Kate Grillot, Yu Chen, Anna Dilhas, Samedy Ouk, Chris Tran, James D. Joseph, John Wongvipat, Nicola J. Clegg
PDF file - 312K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318f3ae7f053ae4cf142c57f94aff43b
https://doi.org/10.1158/0008-5472.22393733.v1
https://doi.org/10.1158/0008-5472.22393733.v1
Autor:
Jeffrey H. Hager, Charles L. Sawyers, Michael E. Jung, Richard A. Heyman, Peter J. Rix, Ouathek Ouerfelli, Nian Wu, Elisa De Stanchina, Nicholas D. Smith, Mark Klang, Peter Smith-Jones, Howard I. Scher, Beatrice Darimont, Celine Bonnefous, Mark R. Herbert, Teresa Wasielewska, John Sensintaffar, Chunyan Cao, Guangbin Yang, Hong Zhao, Jing Qian, Gang Shao, Vivek Arora, Steven Dorow, Anna Aparicio, Ling Cai, Eric D. Bischoff, Kate Grillot, Yu Chen, Anna Dilhas, Samedy Ouk, Chris Tran, James D. Joseph, John Wongvipat, Nicola J. Clegg
PDF file - 151K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2537b6280aa6c75940e1aff9128e4712
https://doi.org/10.1158/0008-5472.22393715
https://doi.org/10.1158/0008-5472.22393715
Autor:
Jeffrey H. Hager, Charles L. Sawyers, Michael E. Jung, Richard A. Heyman, Peter J. Rix, Ouathek Ouerfelli, Nian Wu, Elisa De Stanchina, Nicholas D. Smith, Mark Klang, Peter Smith-Jones, Howard I. Scher, Beatrice Darimont, Celine Bonnefous, Mark R. Herbert, Teresa Wasielewska, John Sensintaffar, Chunyan Cao, Guangbin Yang, Hong Zhao, Jing Qian, Gang Shao, Vivek Arora, Steven Dorow, Anna Aparicio, Ling Cai, Eric D. Bischoff, Kate Grillot, Yu Chen, Anna Dilhas, Samedy Ouk, Chris Tran, James D. Joseph, John Wongvipat, Nicola J. Clegg
PDF file- 366K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a47cb5fd62962d1636eb34a355b1e71
https://doi.org/10.1158/0008-5472.22393727.v1
https://doi.org/10.1158/0008-5472.22393727.v1
Autor:
Jeffrey H. Hager, Charles L. Sawyers, Michael E. Jung, Richard A. Heyman, Peter J. Rix, Ouathek Ouerfelli, Nian Wu, Elisa De Stanchina, Nicholas D. Smith, Mark Klang, Peter Smith-Jones, Howard I. Scher, Beatrice Darimont, Celine Bonnefous, Mark R. Herbert, Teresa Wasielewska, John Sensintaffar, Chunyan Cao, Guangbin Yang, Hong Zhao, Jing Qian, Gang Shao, Vivek Arora, Steven Dorow, Anna Aparicio, Ling Cai, Eric D. Bischoff, Kate Grillot, Yu Chen, Anna Dilhas, Samedy Ouk, Chris Tran, James D. Joseph, John Wongvipat, Nicola J. Clegg
PDF file - 483K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9be4da5cb4d1a3ca1b2f93d23f8117a
https://doi.org/10.1158/0008-5472.22393721.v1
https://doi.org/10.1158/0008-5472.22393721.v1
Autor:
Karensa L. Douglas, Kyoung-Jin Lee, Johnny Y. Nagasawa, Anna Aparicio, Nhin Lu, Andiliy G. Lai, Joshua A. Kaufman, Mehmet Kahraman, Celine Bonnefous, John Sensintaffar, Jeffrey H. Hager, James Joseph, Steven P. Govek, Peter J. Rix, Michael J. Moon, Rene Prudente, Katherine L. Grillot, Julien Jackaline D, Beatrice Darimont, Nicholas D. Smith
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:367-372
Potent estrogen receptor ligands typically contain a phenolic hydrogen-bond donor. The indazole of the selective estrogen receptor degrader (SERD) ARN-810 is believed to mimic this. Disclosed herein is the discovery of ARN-810 analogs which lack this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652ad125c719f124722ac974d5c62830
https://doi.org/10.1016/j.bmcl.2018.12.042
https://doi.org/10.1016/j.bmcl.2018.12.042