Zobrazeno 1 - 10
of 1 007
pro vyhledávání: '"Peter J Hotez"'
Autor:
Duc Minh Nguyen, Cristina Poveda, Jeroen Pollet, Fabian Gusovsky, Maria Elena Bottazzi, Peter J Hotez, Kathryn Marie Jones
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011519 (2023)
BackgroundChagas disease, chronic infection with Trypanosoma cruzi, mainly manifests as cardiac disease. However, the liver is important for both controlling parasite burdens and metabolizing drugs. Notably, high doses of anti-parasitic drug benznida
Externí odkaz:
https://doaj.org/article/1a67838d992942c3894c9ef56f930384
Autor:
Peter J Hotez, Salim S Abdool Karim, Lois Privor-Dumm, Jerome H Kim, Sarah Gilbert, Didi Thompson, Jean-Louis Excler
Publikováno v:
BMJ Global Health, Vol 8, Iss 6 (2023)
Although significant progress has been made in achieving goals for COVID-19 vaccine access, the quest for equity and justice remains an unfinished agenda. Vaccine nationalism has prompted calls for new approaches to achieve equitable access and justi
Externí odkaz:
https://doaj.org/article/846698c9e26043098c81582539ed6934
Autor:
Peter J Hotez, Lois Privor-Dumm, Melanie Saville, Jerome H Kim, Sarah Gilbert, Salim Abdool-Karim, Didi Thompson, Jean-Louis Excler
Publikováno v:
BMJ Global Health, Vol 8, Iss 6 (2023)
The COVID-19 pandemic triggered a sense of vulnerability and urgency that led to concerted actions by governments, funders, regulators and industry to overcome traditional challenges for the development of vaccine candidates and to reach authorisatio
Externí odkaz:
https://doaj.org/article/c60cd7d6c7bb46068a2dfbdc2736279f
Autor:
Peter J Hotez, Lois Privor-Dumm, Melanie Saville, Jerome H Kim, Sarah Gilbert, Salim Abdool-Karim, Didi Thompson, Jean-Louis Excler
Publikováno v:
BMJ Global Health, Vol 8, Iss 6 (2023)
Through the experiences gained by accelerating new vaccines for both Ebola virus infection and COVID-19 in a public health emergency, vaccine development has benefited from a ‘multiple shots on goal’ approach to new vaccine targets. This approach
Externí odkaz:
https://doaj.org/article/92d6ee737c1d4e9cb905d47e32dd3d83
Autor:
David J Diemert, Rodrigo Correa-Oliveira, Carlo Geraldo Fraga, Frederico Talles, Marcella Rezende Silva, Shital M Patel, Shirley Galbiati, Jessie K Kennedy, Jordan S Lundeen, Maria Flavia Gazzinelli, Guangzhao Li, Lara Hoeweler, Gregory A Deye, Maria Elena Bottazzi, Peter J Hotez, Hana M El Sahly, Wendy A Keitel, Jeffrey Bethony, Robert L Atmar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 3, p e0011236 (2023)
BackgroundRecombinant Schistosoma mansoni Tetraspanin-2 formulated on Alhydrogel (Sm-TSP-2/Alhydrogel) is being developed to prevent intestinal and hepatic disease caused by S. mansoni. The tegumentary Sm-TSP-2 antigen was selected based on its uniqu
Externí odkaz:
https://doaj.org/article/be96f1829afd483789795737d1949860
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 10, p e0002482 (2023)
There is broad consensus that the global response to the Covid-19 pandemic was inadequate, leading to unacceptable levels of avoidable morbidity and mortality. Three strategic missteps led to the lack of equitable vaccine access: The heavy reliance o
Externí odkaz:
https://doaj.org/article/e12daef2b354473dac4c04064792967e
Autor:
Sarah M Bartsch, MPH, Kelly J O'Shea, BSFS, Kevin L Chin, MPH, Ulrich Strych, PhD, Marie C Ferguson, MSPH, Maria Elena Bottazzi, ProfPhD, Patrick T Wedlock, MSPH, Sarah N Cox, MSPH, Sheryl S Siegmund, MS, Peter J Hotez, ProfMD, Bruce Y Lee, ProfMD
Publikováno v:
The Lancet Public Health, Vol 7, Iss 4, Pp e356-e365 (2022)
Summary: Background: Face mask wearing has been an important part of the response to the COVID-19 pandemic. As vaccination coverage progresses in countries, relaxation of such practices is increasing. Subsequent COVID-19 surges have raised the questi
Externí odkaz:
https://doaj.org/article/6e44642944874399bae131fb47137b64
Autor:
Kala Pham, Peter J Hotez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/335fd5fdd1a1401ca88156e616cd8a31
Autor:
Peter J Hotez
Publikováno v:
PLOS Global Public Health, Vol 2, Iss 10, p e0001173 (2022)
Externí odkaz:
https://doaj.org/article/4f874f70d3534286b112901940e4fb9f
Autor:
Madeleine Eunice Betouke Ongwe, Yoanne D Mouwenda, Koen A Stam, Peter G Kremsner, Bertrand Lell, David Diemert, Jeff Bethony, Maria E Bottazzi, Peter J Hotez, Remko V Leeuwen, Martin P Grobusch, Ayola A Adegnika, Oleg A Mayboroda, Maria Yazdanbakhsh
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0275013 (2022)
Metabolomics provides a powerful tool to study physiological changes in response to various perturbations such as vaccination. We explored whether metabolomic changes could be seen after vaccination in a phase I trial where Gabonese adults living eit
Externí odkaz:
https://doaj.org/article/ed445e508fab47d0a4352a9fcd870d4f