Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Peter J Cabot"'
Autor:
Naghmeh Hajarol Asvadi, Michael Morgan, Herath M Herath, Amitha K Hewavitharana, P Nicholas Shaw, Peter J Cabot
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90380 (2014)
A large body of evidence now exists for the immune cell expression, production, and the release of beta-endorphin (BE 1-31) within inflamed tissue. The inflammatory milieu is characterised by increased acidity, temperature and metabolic activity. Wit
Externí odkaz:
https://doaj.org/article/4795f4f2306449a9baf78549202e4c76
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77903 (2013)
Tissue damage or pathological alterations are not detectable in the majority of people with whiplash associated disorders (WAD). Widespread hyperalgisa, morphological muscle changes and psychological distress are common features of WAD. However littl
Externí odkaz:
https://doaj.org/article/6d770cf1baa9408396e83f02b08fd3b2
Autor:
Felicity M Davis, Amelia A Peters, Desma M Grice, Peter J Cabot, Marie-Odile Parat, Sarah J Roberts-Thomson, Gregory R Monteith
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36923 (2012)
In addition to their well-defined roles in replenishing depleted endoplasmic reticulum (ER) Ca(2+) reserves, molecular components of the store-operated Ca(2+) entry pathway regulate breast cancer metastasis. A process implicated in cancer metastasis
Externí odkaz:
https://doaj.org/article/b5284b525f9f4b0f8e4fe7352e5a9b47
Publikováno v:
Frontiers in Pharmacology, Vol 2 (2011)
Morphine is the core of perioperative pain management. However, when it comes to cancer surgery the possibility that this drug might affect tumor recurrence and metastasis has raised concerns. The results of two recent retrospective clinical trials i
Externí odkaz:
https://doaj.org/article/335c636e79f8450fb318247e8eb96579
Autor:
Felicity M Davis, Paraic A Kenny, Eliza T-L Soo, Bryce J W van Denderen, Erik W Thompson, Peter J Cabot, Marie-Odile Parat, Sarah J Roberts-Thomson, Gregory R Monteith
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23464 (2011)
BackgroundThe microenvironment plays a pivotal role in tumor cell proliferation, survival and migration. Invasive cancer cells face a new set of environmental challenges as they breach the basement membrane and colonize distant organs during the proc
Externí odkaz:
https://doaj.org/article/f4b5706716164733ba724fc70c52c898
Autor:
Priscilla Galante, Gabriel A. A. Campos, Jacqueline C. G. Moser, Danubia B. Martins, Marcia P. dos Santos Cabrera, Marisa Rangel, Luiza C. Coelho, Karina S. Simon, Veronica M. Amado, Jessica de A. I. Muller, Johannes Koehbach, Rink-Jan Lohman, Peter J. Cabot, Irina Vetter, David J. Craik, Monica C. Toffoli-Kadri, Victoria Monge-Fuentes, Jair T. Goulart, Elisabeth F. Schwartz, Luciano P. Silva, Anamelia L. Bocca, Márcia R. Mortari
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Animal venoms are rich sources of neuroactive compounds, including anti-inflammatory, antiepileptic, and antinociceptive molecules. Our study identified a protonectin peptide from the wasp Parachartergus fraternus' venom using mass spectrome
Externí odkaz:
https://doaj.org/article/b67d9db1535243309705120d264359b7
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Kappa opioid receptors have exceptional potential as an analgesic target, seemingly devoid of many problematic Mu receptor side-effects. Kappa-selective, small molecule pharmaceutical agents have been developed, but centrally mediated side-effects li
Externí odkaz:
https://doaj.org/article/3013e09cf1bb4fb3bcfd3869ba7c4bed
Autor:
Fahad Ahmed, Benjamin Tscharke, Jake W. O’Brien, Wayne D. Hall, Peter J. Cabot, P. Marcin Sowa, Saer Samanipour, Kevin V. Thomas
Publikováno v:
Environmental Science & Technology. 57:1712-1720
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f769a4ee489dfe200a0ef1ee5b2a74d
https://doi.org/10.1021/acs.est.2c06691
https://doi.org/10.1021/acs.est.2c06691
Autor:
Marie-Odile Parat, David Sturgess, Kim-Anh Lê Cao, Carl M.J. Kirkpatrick, Paul N. Shaw, Peter J. Cabot, Zeyad D. Nassar, Kye Gregory, Tharindu Vithanage, Nicholas Matigian, Nan Xie
Relationship between cAMP measurements and morphine mouse administration, and in vitro morphine-spiked plasma concentration. Data was analysed with GraphPad Prism software (v. 7.00). A) Mice were treated with saline or morphine (1 or 10 mg/kg) and pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afb43f3d8a465105bd158bb7af827b9
https://doi.org/10.1158/1078-0432.22470366.v1
https://doi.org/10.1158/1078-0432.22470366.v1
Autor:
Marie-Odile Parat, David Sturgess, Kim-Anh Lê Cao, Carl M.J. Kirkpatrick, Paul N. Shaw, Peter J. Cabot, Zeyad D. Nassar, Kye Gregory, Tharindu Vithanage, Nicholas Matigian, Nan Xie
Purpose: The purpose of this study is to investigate the potential interplay between opioid analgesia and tumor metastasis through modulation of μ-opioid receptor (MOR), Toll-like receptor 4 (TLR4) activation, and matrix degradation potential.Experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82514a6f7faab9b066ce3f4eca01fc68
https://doi.org/10.1158/1078-0432.c.6527538
https://doi.org/10.1158/1078-0432.c.6527538