Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Peter J, van den Elsen"'
Autor:
Claudia Sestito, John J. P. Brevé, Marja C. J. A. van Eggermond, Joep Killestein, Charlotte E. Teunissen, Joram van Rossum, Micha M. M. Wilhelmus, Benjamin Drukarch, Peter J. van den Elsen, Anne-Marie van Dam
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-12 (2017)
Abstract Background Leukocyte infiltration into the central nervous system is an important feature of multiple sclerosis (MS) pathology. Among the infiltrating cells, monocytes comprise the largest population and are considered to play a dual role in
Externí odkaz:
https://doaj.org/article/a5bd94e19988421e8d28186597e115ae
Autor:
Rob C M de Jong, Mark M Ewing, Margreet R de Vries, Jacco C Karper, Antonius J N M Bastiaansen, Hendrika A B Peters, Fabiana Baghana, Peter J van den Elsen, Céline Gongora, J Wouter Jukema, Paul H A Quax
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185820 (2017)
Genetic P300/CBP-associated factor (PCAF) variation affects restenosis-risk in patients. PCAF has lysine acetyltransferase activity and promotes nuclear factor kappa-beta (NFκB)-mediated inflammation, which drives post-interventional intimal hyperpl
Externí odkaz:
https://doaj.org/article/7fba7a515cb24939b510a5d62c71ae04
Publikováno v:
Biology, Vol 1, Iss 3, Pp 869-879 (2012)
The chemokine receptor CCR5 regulates trafficking of immune cells of the lymphoid and the myeloid lineage (such as monocytes, macrophages and immature dendritic cells) and microglia. Because of this, there is an increasing recognition of the importan
Externí odkaz:
https://doaj.org/article/c53c3015821440809b8902c9e0ce8ed4
Autor:
T Huibertus van Essen, Sake I van Pelt, Inge H G Bronkhorst, Mieke Versluis, Fariba Némati, Cécile Laurent, Gregorius P M Luyten, Thorbald van Hall, Peter J van den Elsen, Pieter A van der Velden, Didier Decaudin, Martine J Jager
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164292 (2016)
Uveal melanoma (UM) with an inflammatory phenotype, characterized by infiltrating leukocytes and increased human leukocyte antigen (HLA) expression, carry an increased risk of death due to metastases. These tumors should be ideal for T-cell based the
Externí odkaz:
https://doaj.org/article/81eba8a66d0847c4b825c012cde07949
Publikováno v:
Vijayan, S, Sidiq, T, Yousuf, S, van den Elsen, P J & Kobayashi, K S 2019, ' Class I transactivator, NLRC5: a central player in the MHC class I pathway and cancer immune surveillance ', Immunogenetics, vol. 71, no. 3, pp. 273-282 . https://doi.org/10.1007/s00251-019-01106-z
Major histocompatibility complex (MHC) class I and class II molecules play critical roles in the activation of the adaptive immune system by presenting antigens to CD8+ and CD4+ T cells, respectively. Although it has been well known that CIITA (MHC c
Autor:
Peter J van den Elsen
Publikováno v:
Frontiers in Immunology, Vol 2 (2011)
MHC-I and MHC-II molecules play an essential role in the immune response to pathogens by virtue of their ability to present peptides to CD8+ and CD4+ T cells, respectively. Given this critical role, MHC-I and MHC-II genes are regulated in a tight fas
Externí odkaz:
https://doaj.org/article/5043276d97b84a3db225a604605748c7
Autor:
Marion H. König, Hans Gelderblom, N.G. Dekker-Ensink, Peter J. K. Kuppen, Anniek Zaalberg, Marloes Swets, Peter J. van den Elsen, Cornelis J.H. van de Velde
Publikováno v:
Human Immunology, 77(9), 773-779
Swets, M, Koenig, M H, Zaalberg, A, Dekker-Ensink, N G, Gelderblom, H, van de Velde, C J H, van den Elsen, P J & Kuppen, P J K 2016, ' HLA-G and classical HLA class I expression in primary colorectal cancer and associated liver metastases ', Human Immunology, vol. 77, no. 9, pp. 773-779 . https://doi.org/10.1016/j.humimm.2016.03.001
Human Immunology, 77(9), 773-779. Elsevier Inc.
Swets, M, Koenig, M H, Zaalberg, A, Dekker-Ensink, N G, Gelderblom, H, van de Velde, C J H, van den Elsen, P J & Kuppen, P J K 2016, ' HLA-G and classical HLA class I expression in primary colorectal cancer and associated liver metastases ', Human Immunology, vol. 77, no. 9, pp. 773-779 . https://doi.org/10.1016/j.humimm.2016.03.001
Human Immunology, 77(9), 773-779. Elsevier Inc.
De novo expression of HLA-G has been demonstrated in colorectal cancer. HLA-G, amongst others, inhibits natural killer cell function, contributing to host immune defense evasion. Another mechanism to escape anti-tumor immunity is loss of HLA class I.
Autor:
Belinda W. C. Ommering, Peter J. van den Elsen, Jolanda van der Zee, Friedo W. Dekker, Carolina R. Jost
Publikováno v:
Medical Science Educator
Physician-scientists are urgently needed to make progress in the dynamic world of medical healthcare. Currently, there is a worldwide shortage in physicians pursuing a scientific career. Actively engaging students in research in early stages of medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357f0757eec6d05a87fb56928b556e32
https://hdl.handle.net/1887/95402
https://hdl.handle.net/1887/95402
Autor:
Ruud H. Wijdeven, Annet F Wierenga-Wolf, Jimmy J Akkermans, Jacques Neefjes, Peter J. van den Elsen, Rogier Q. Hintzen, Marvin M van Luijn
Publikováno v:
EMBO Reports, 19(9):e45553. Wiley-Blackwell
EMBO Reports, 19(9)
EMBO Reports
EMBO Reports, 19(9)
EMBO Reports
The cytokine interferon‐γ (IFNγ) can induce expression of MHC class II (MHCII) on many different cell types, leading to antigen presentation to CD4(+) T cells and immune activation. This has also been linked to anti‐tumour immunity and graft‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615b545fa94ac8548e630d4784d80c98
https://pure.eur.nl/en/publications/99d6341b-17e1-48af-b310-23386656bdc8
https://pure.eur.nl/en/publications/99d6341b-17e1-48af-b310-23386656bdc8
Autor:
Benjamin Drukarch, Micha M.M. Wilhelmus, Anne-Marie van Dam, Joep Killestein, Peter J. van den Elsen, Charlotte E. Teunissen, John J. P. Brevé, Joram van Rossum, Claudia Sestito, Marja C.J.A. van Eggermond
Publikováno v:
Sestito, C, Brevé, J J P, van Eggermond, M C J A, Killestein, J, Teunissen, C E, van Rossum, J, Wilhelmus, M M M, Drukarch, B, van den Elsen, P J & van Dam, A-M 2017, ' Monocyte-derived tissue transglutaminase in multiple sclerosis patients : reflecting an anti-inflammatory status and function of the cells? ', Journal of Neuroinflammation, vol. 14, no. 1, pp. 257 . https://doi.org/10.1186/s12974-017-1035-y
Journal of Neuroinflammation, 14(1). BioMed Central
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-12 (2017)
Journal of Neuroinflammation, 14
Journal of Neuroinflammation, 14(1). BioMed Central
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-12 (2017)
Journal of Neuroinflammation, 14
Background Leukocyte infiltration into the central nervous system is an important feature of multiple sclerosis (MS) pathology. Among the infiltrating cells, monocytes comprise the largest population and are considered to play a dual role in the cour