Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter J, Schlegel"'
Autor:
Nafisa Burhani, Hani M. Babiker, Emad Elquza, Andrea J. Bullock, Ely Benaim, Allyson J. Ocean, Lee G. Hicks, Peter J. Schlegel, Christine B. Peterson, Daruka Mahadevan, Mitesh J. Borad, Callie Heaton
Publikováno v:
Investigational New Drugs. 40:81-90
Background RX-3117 is an oral small molecule antimetabolite, cyclopentyl pyrimidyl nucleoside that is activated by cancer cells over-expressing uridine cytidine kinase 2 (UCK2). Single agent RX-3117 demonstrated efficacy in a phase I trial in patient
Autor:
Hani, Babiker, Peter J, Schlegel, Lee G, Hicks, Andrea J, Bullock, Nafisa, Burhani, Daruka, Mahadevan, Emad, Elquza, Mitesh J, Borad, Ely, Benaim, Christine, Peterson, Callie, Heaton, Allyson J, Ocean
Publikováno v:
Investigational new drugs. 40(1)
Background RX-3117 is an oral small molecule antimetabolite, cyclopentyl pyrimidyl nucleoside that is activated by cancer cells over-expressing uridine cytidine kinase 2 (UCK2). Single agent RX-3117 demonstrated efficacy in a phase I trial in patient
Autor:
Lee G. Hicks, Peter J. Schlegel, Hani M. Babiker, Andrea J. Bullock, Nafisa Burhani, Callie Heaton, Christine B. Peterson, Ely Benaim, Allyson J. Ocean
Publikováno v:
Journal of Clinical Oncology. 37:420-420
420 Background: RX-3117 is an oral small molecule antimetabolite, cyclopentyl pyrimidyl nucleoside that is activated by cancer-enriched uridine cytidine kinase 2. Single agent RX-3117 has demonstrated efficacy in a phase III single agent clinical stu
Autor:
Roger M. Lyons, Yunfei Wang, Philip Y. Dien, Nicholas J. Di Bella, Robert N. Raju, Julie Boston, Kathryn S. Kolibaba, Svetislava J. Vukelja, David Barrera, Raymond Taetle, Peter J. Schlegel, Thomas E. Boyd, Lina Asmar, Kristi A. Boehm, Ernest W. Cochran
Publikováno v:
Blood. 115:475-480
This study evaluated the efficacy and safety of single-agent bortezomib in indolent B-cell lymphoma that had relapsed from or was refractory to rituximab. Sixty patients enrolled: 59 were treated with bortezomib 1.3 mg/m2 on days 1, 4, 8, and 11 for
Publikováno v:
The American Journal of Medicine. 107:643-645
Publikováno v:
Journal of Immunotherapy. 23:507-508
Autor:
Lina Asmar, Yunfei Wang, Kristi A Boehm, Julie Boston, Svetislava J Vukelja, Peter J Schlegel, Roger M. Lyons, David Hakimian, Philip Dien, Ernest Cochran, David N Barrera, Robert N Raju, Thomas E Boyd, Kathryn S. Kolibaba, Raymond Taetle, Nicholas Di Bella
Publikováno v:
Blood. 112:1572-1572
This study was designed to evaluate the efficacy and safety of bortezomib as monotherapy in patients (pts) with indolent B-cell lymphoma who have relapsed following, or who are refractory to, rituximab therapy. A total of 60 patients enrolled and 59