Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Peter J, Hanley"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Initially, the two members of class 18 myosins, Myo18A and Myo18B, appeared to exhibit highly divergent functions, complicating the assignment of class-specific functions. However, the identification of a striated muscle-specific isoform of Myo18A, M
Externí odkaz:
https://doaj.org/article/f8d9a9c94e104495bd69f504cd8b95cc
Autor:
Peter J. Hanley
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Prostatic acid phosphatase (PAP) exists as two splice variants, secreted PAP and transmembrane PAP, the latter of which is implicated in antinociceptive signaling in dorsal root ganglia. However, PAP is predominantly expressed in the prostate gland a
Externí odkaz:
https://doaj.org/article/56b792daa04148988909fdaecc997887
Autor:
Antonella Russo, Hendrik Schürmann, Matthias Brandt, Katja Scholz, Anna Livia L. Matos, David Grill, Julian Revenstorff, Maximilian Rembrink, Meike von Wulffen, Lena Fischer‐Riepe, Peter J. Hanley, Hans Häcker, Monika Prünster, Francisco Sánchez‐Madrid, Sven Hermann, Luisa Klotz, Volker Gerke, Timo Betz, Thomas Vogl, Johannes Roth
Publikováno v:
Advanced Science, Vol 9, Iss 36, Pp n/a-n/a (2022)
Abstract Mechanisms keeping leukocytes distant of local inflammatory processes in a resting state despite systemic release of inflammatory triggers are a pivotal requirement for avoidance of overwhelming inflammation but are ill defined. Dimers of th
Externí odkaz:
https://doaj.org/article/436a845c56a94e71958ce48320f05a72
Autor:
Esther van den Bos, Stefan Walbaum, Benjamin Ambrosy, Giulio Innamorati, Thomas M. Wilkie, Peter J. Hanley, Markus Horsthemke, Nina Wettschureck, Anne C. Bachg
Publikováno v:
J Biol Chem
G protein–coupled receptor signaling is required for the navigation of immune cells along chemoattractant gradients. However, chemoattractant receptors may couple to more than one type of heterotrimeric G protein, each of which consists of a Gα, G
Autor:
Markus Horsthemke, Peter J. Hanley, Anne C. Bachg, Stefan Walbaum, Attila Mócsai, Benjamin Ambrosy, Jeanette H. W. Leusen, Paula Schütz
Publikováno v:
The Journal of Biological Chemistry
A long-standing hypothesis is that complement receptors (CRs), especially CR3, mediate sinking phagocytosis, but evidence is lacking. Alternatively, CRs have been reported to induce membrane ruffles or phagocytic cups, akin to those induced by Fcγ r
Publikováno v:
Journal of Visualized Experiments.
Chemotaxis is receptor-mediated guidance of cells along a chemical gradient, whereas chemokinesis is the stimulation of random cell motility by a chemical. Chemokinesis and chemotaxis are fundamental for the mobilization and deployment of immune cell
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030380618
Class IX myosins are simultaneously motor and signaling molecules. In addition to myosin class-specific functions of the tail region, they feature unique motor properties. Within their motor region they contain a long insertion with a calmodulin- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1cc13a378a284544f11f3a15f602145
https://doi.org/10.1007/978-3-030-38062-5_16
https://doi.org/10.1007/978-3-030-38062-5_16
Autor:
Peter J. Hanley
Publikováno v:
Reframing Cult Westerns.
Autor:
Sven Moyzio, Markus Horsthemke, Michael Sixt, Sandra A. Hemkemeyer, Martin Bähler, Roland Wedlich-Söldner, Peter J. Hanley, Sebastian Tacke, Anne C. Bachg, Barbara Müther, Katharina Groll
Publikováno v:
Journal of Biological Chemistry. 292:7258-7273
Macrophage filopodia, finger-like membrane protrusions, were first implicated in phagocytosis more than 100 years ago, but little is still known about the involvement of these actin-dependent structures in particle clearance. Using spinning disk conf
Autor:
Wolfgang A. Linke, Markus Horsthemke, Ursula Ravens, Frank U. Müller, Matthias D. Seidl, Monika Stoll, Pim R.R. van Gorp, Peter J. Hanley, Boris V. Skryabin, Thomas Zobel, Andreas Unger, Antoine A.F. de Vries, Ulrike Honnert, Anne C. Bachg, Martin Bähler, Lauryl M.J. Nutter, Sven Bogdan
Whereas myosin 18B (Myo18B) is known to be a critical sarcomeric protein, the function of myosin 18A (Myo18A) is unclear, although it has been implicated in cell motility and Golgi shape. Here, we show that homozygous deletion (homozygous tm1a, tm1b,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f1d2194887850de915051658f22e31
https://hdl.handle.net/1887/122160
https://hdl.handle.net/1887/122160