Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Peter J, Gawne"'
Autor:
Anna Lisa Palange, Daniele Di Mascolo, Miguel Ferreira, Peter J. Gawne, Raffaele Spanò, Alessia Felici, Luca Bono, Thomas Lee Moore, Marco Salerno, Andrea Armirotti, Paolo Decuzzi
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract Breast cancer cell colonization of the lungs is associated with a dismal prognosis as the distributed nature of the disease and poor permeability of the metastatic foci challenge the therapeutic efficacy of small molecules, antibodies, and n
Externí odkaz:
https://doaj.org/article/ea75570cde734811a99e5a807607e5b2
Autor:
Peter J. Gawne, Sara M.A. Pinto, Karin M. Nielsen, George P. Keeling, Mariette M. Pereira, Rafael T. M. de Rosales
Publikováno v:
Gawne, P, Pinto, S, Nielsen, K, Keeling, G, Pereira, M & T. M. de Rosales, R 2022, ' Microwave-assisted synthesis of [ 52 Mn]Mn-porphyrins: Applications in cell and liposome radiolabelling ', Nuclear Medicine and Biology, vol. 114-115, pp. 6-17 . https://doi.org/10.1016/j.nucmedbio.2022.08.006
Background: Manganese porphyrins have several therapeutic/imaging applications, including their use as radioprotectants (in clinical trials) and as paramagnetic MRI contrast agents. The affinity of porphyrins for lipid bilayers also makes them candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9a40c1ccafe0b79b6170475594e8aa
https://kclpure.kcl.ac.uk/en/publications/d9e2f957-f2d6-490d-94ef-532ac10c842b
https://kclpure.kcl.ac.uk/en/publications/d9e2f957-f2d6-490d-94ef-532ac10c842b
Publikováno v:
Chemical Society Reviews. 50:3355-3423
Nanomaterials offer unique physical, chemical and biological properties of interest for medical imaging and therapy. Over the last two decades, there has been an increasing effort to translate nanomaterial-based medicinal products (so-called nanomedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6213fece58f1817a8e973ad389e88906
https://doi.org/10.1039/d0cs00384k
https://doi.org/10.1039/d0cs00384k
Publikováno v:
Chemical reviews. 122(11)
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical application in a rational manner depends on reliable, clinically applicable methods for determining the fate and trafficking of therapeutic cells in vivo usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfe00ff7cb818777c9631aca5868b9e1
https://pubmed.ncbi.nlm.nih.gov/35549242
https://pubmed.ncbi.nlm.nih.gov/35549242
Autor:
Peter J, Gawne, Sara M A, Pinto, Karin M, Nielsen, George P, Keeling, Mariette M, Pereira, Rafael, T M de Rosales
Publikováno v:
Nuclear medicine and biology.
Manganese porphyrins have several therapeutic/imaging applications, including their use as radioprotectants (in clinical trials) and as paramagnetic MRI contrast agents. The affinity of porphyrins for lipid bilayers also makes them candidates for cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e42cc8a6a8c13efb36b2ac936894418e
https://pubmed.ncbi.nlm.nih.gov/36088876
https://pubmed.ncbi.nlm.nih.gov/36088876
Autor:
Peter J. Gawne, Sara M. A. Pinto, Karin M. Nielsen, George P. Keeling, Mariette M. Pereira, Rafael T. M. de Rosales
Manganese porphyrins have several therapeutic/imaging applications, including their use as radioprotectants (in clinical trials) and as paramagnetic MRI contrast agents. The affinity of porphyrins for lipid bilayers also makes them candidates for cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff828e348b3f958b8b71ba4c02a5b8a3
https://doi.org/10.26434/chemrxiv-2021-v8wm5-v2
https://doi.org/10.26434/chemrxiv-2021-v8wm5-v2
Autor:
Samantha Y.A. Terry, Andrew P. Cope, Peter J. Gawne, Fiona Clarke, Keren Turjeman, Yechezkel Barenholz, Rafael Torres Martin de Rosales, Nicholas J. Long
Publikováno v:
Theranostics
Gawne, P J, Clarke, F, Turjeman, K, Cope, A P, Long, N J, Barenholz, Y, Terry, S Y A & T. M. de Rosales, R 2020, ' PET Imaging of Liposomal Glucocorticoids using 89Zr-oxine: Theranostic Applications in Inflammatory Arthritis ', Theranostics, vol. 10, no. 9, pp. 3867-3879 . https://doi.org/10.7150/thno.40403
Gawne, P J, Clarke, F, Turjeman, K, Cope, A P, Long, N J, Barenholz, Y, Terry, S Y A & T. M. de Rosales, R 2020, ' PET Imaging of Liposomal Glucocorticoids using 89Zr-oxine: Theranostic Applications in Inflammatory Arthritis ', Theranostics, vol. 10, no. 9, pp. 3867-3879 . https://doi.org/10.7150/thno.40403
The encapsulation of Glucocorticoids (GCs) into long-circulating liposomes (LCLs) is a proven strategy to reduce the side effects of glucocorticoids and improve the treatment of inflammatory diseases, such as rheumatoid arthritis (RA). With the aim o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b199a14f854d533a90da453ba77f54a
http://europepmc.org/articles/PMC7086351
http://europepmc.org/articles/PMC7086351
Autor:
Michelle T. Ma, Ingebjørg N Hungnes, Fiona Clarke, Paul G. Pringle, Thomas R. Eykyn, Philip J. Blower, Fahad Al-Salemee, Samantha Y.A. Terry, R. Andrew Atkinson, Peter J. Gawne
Publikováno v:
Hungnes, I N, Al-Salemee, F, Gawne, P J, Eykyn, T, Atkinson, R A, Terry, S Y A, Clarke, F, Blower, P J, Pringle, P G & Ma, M T 2021, ' One-step, kit-based radiopharmaceuticals for molecular SPECT imaging : a versatile diphosphine chelator for 99mTc radiolabelling of peptides ', Dalton Transactions, vol. 50, no. 44, pp. 16156-16165 . https://doi.org/10.1039/d1dt03177e
Dalton Transactions
Dalton Transactions, Royal Society of Chemistry, 2021, 50 (44), pp.16156-16165. ⟨10.1039/d1dt03177e⟩
Hungnes, I, Al Salemee, F, Gawne, P, Eykyn, T R, Atkinson, A, Terry, S, Clarke, F, Blower, P J, Pringle, P G & Ma, M 2021, ' One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for 99m Tc radiolabelling of peptides ', Dalton Transactions, vol. 50, no. 44, pp. 16156-16165 . https://doi.org/10.1039/D1DT03177E
Dalton Transactions
Dalton Transactions, Royal Society of Chemistry, 2021, 50 (44), pp.16156-16165. ⟨10.1039/d1dt03177e⟩
Hungnes, I, Al Salemee, F, Gawne, P, Eykyn, T R, Atkinson, A, Terry, S, Clarke, F, Blower, P J, Pringle, P G & Ma, M 2021, ' One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for 99m Tc radiolabelling of peptides ', Dalton Transactions, vol. 50, no. 44, pp. 16156-16165 . https://doi.org/10.1039/D1DT03177E
Radiotracers labelled with technetium-99m (99mTc) enable accessible diagnostic imaging of disease, provided that radiotracer preparation is simple. Whilst 99mTc radiopharmaceuticals for imaging perfusion are routinely prepared from kits, and regularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9215b53701872aac69e2b7a2f051abaa
https://hdl.handle.net/1983/fb96ed35-28e8-45e8-8768-7b359c87aac6
https://hdl.handle.net/1983/fb96ed35-28e8-45e8-8768-7b359c87aac6
Autor:
Sara M. A. Pinto, Rafael Torres Martin de Rosales, Peter J. Gawne, Mariette M. Pereira, Karin M. Nielsen
Manganese porphyrins have several therapeutic/imaging applications; including their use as radioprotectants (in clinical trials), and as paramagnetic MRI contrast agents. The affinity of porphyrins for lipid bilayers also makes them candidates for ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ca1db1f78b9ba3b1458993827da2bd
https://doi.org/10.26434/chemrxiv-2021-v8wm5
https://doi.org/10.26434/chemrxiv-2021-v8wm5
Autor:
Ingebjørg N, Hungnes, Fahad, Al-Salemee, Peter J, Gawne, Thomas, Eykyn, R Andrew, Atkinson, Samantha Y A, Terry, Fiona, Clarke, Philip J, Blower, Paul G, Pringle, Michelle T, Ma
Publikováno v:
Dalton Transactions (Cambridge, England : 2003)
Radiotracers labelled with technetium-99m (99mTc) enable accessible diagnostic imaging of disease, provided that radiotracer preparation is simple. Whilst 99mTc radiopharmaceuticals for imaging perfusion are routinely prepared from kits, and regularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::919a396fdd0fd9be97ca0f7f4f7c2cfe
https://pubmed.ncbi.nlm.nih.gov/34704995
https://pubmed.ncbi.nlm.nih.gov/34704995