Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Peter Iveson"'
Autor:
Eric O. Aboagye, Duncan Hiscock, Peter Iveson, Giampaolo Tomasi, Maciej Kaliszczak, Quang-Dé Nguyen, Susan Hoppmann, Sebastian Trousil
PDF file - 999K, Supplementary Figure S1: Scheme of FASTlab-compatible automated synthesis of 18FGE-226. Supplementary Figure S2. Interaction of GE-226 with HER2 as determined by Surface Plasmon Resonance. Supplementary Figure S3: Tracer uptake is de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9f3000c23d0e017655ced9d9f81488
https://doi.org/10.1158/1078-0432.22451966
https://doi.org/10.1158/1078-0432.22451966
Autor:
Eric O. Aboagye, Duncan Hiscock, Peter Iveson, Giampaolo Tomasi, Maciej Kaliszczak, Quang-Dé Nguyen, Susan Hoppmann, Sebastian Trousil
Purpose: Expression of HER2 has profound implications on treatment strategies in various types of cancer. We investigated the specificity of radiolabeled HER2-targeting ZHER2:2891 Affibody, [18F]GE-226, for positron emission tomography (PET) imaging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fafd75f8919e1a457dc8e87f599ace
https://doi.org/10.1158/1078-0432.c.6522347
https://doi.org/10.1158/1078-0432.c.6522347
Autor:
Julian Grigg, Duncan Hiscock, Bard Indrevoll, Lone Omtvedt, Matthias Glaser, Dimitrios Mantzilas, Sajinder K. Luthra, Shales Jonathan Robert, Peter Iveson
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:925-932
An 18 F-labelled human epidermal growth factor receptor (HER2) receptor binding radiotracer is a potential tool to non-invasively identify HER2 positive tumour lesions in subjects with recurrent metastatic breast cancer. Having explored the manual ra
Autor:
Matthias Glaser, Bard Indrevoll, Joseph Arukwe, Antonios Danikas, Anthony Wilson, Duncan Hiscock, Susan Hoppmann, Rajiv Bhalla, Peter Iveson
Publikováno v:
Journal of Nuclear Medicine. 54:1981-1988
Human epidermal growth factor receptor (HER2)–targeted Affibody molecules radiolabeled with 18F allow the noninvasive assessment of HER2 status in vivo through PET imaging. Such agents have the potential to improve patient management by selecting i
Autor:
Line Roed, Paul Evans, Andreas Gram, Inger Oulie, Henrik Rasmussen, Ben Newton, Lars-G. Wistrand, Derek Grant, Gunnar Hagelin, Peter Iveson, Mikkel Thaning, Astri Rogstad
Publikováno v:
Acta Radiologica. 51:1014-1020
Background: Contrast-induced nephrotoxicity is a significant risk when using radiographic contrast media clinically, especially in high risk patients. Consequently, there is a need for a new contrast agent with improved clinical safety with regards t
Imaging has played an important part in the diagnosis of disease and development of the understanding of the underlying disease mechanisms and is now poised to make an impact in the development of new pharmaceuticals. This chapter discusses the under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c016dcd82a33a85385f3b10a4f5d537c
https://doi.org/10.1016/bs.pmch.2014.10.002
https://doi.org/10.1016/bs.pmch.2014.10.002
Autor:
Matthias, Glaser, Peter, Iveson, Susan, Hoppmann, Bård, Indrevoll, Anthony, Wilson, Joseph, Arukwe, Antonios, Danikas, Rajiv, Bhalla, Duncan, Hiscock
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 55(6)
Autor:
Eric O. Aboagye, Duncan Hiscock, Sebastian Trousil, Peter Iveson, Maciej Kaliszczak, Susan Hoppmann, Quang-Dé Nguyen, Giampaolo Tomasi
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 20(6)
Purpose: Expression of HER2 has profound implications on treatment strategies in various types of cancer. We investigated the specificity of radiolabeled HER2-targeting ZHER2:2891 Affibody, [18F]GE-226, for positron emission tomography (PET) imaging.
Autor:
Peter Iveson, Matthew Morrison, Yana K. Reshetnyak, Edvin Wilhelm Johannesen, Sven Macholl, Donald M. Engelman, Oleg A. Andreev, Bente E. Arbo
Publikováno v:
Molecular imaging and biology. 14(6)
A novel molecular imaging agent has been developed recently, which stains tissues of low extracellular pH [pH (low) insertion peptide, pHLIP(®)]. A pH-dependent process of peptide folding and insertion into cell membranes has been found in vitro. Ta
Autor:
Peter Iveson, Johanna Haukkala, Pia Leppänen, Anne Roivainen, Jukka Laine, Hege Karlsen, Seppo Ylä-Herttula, Pauliina Luoto, Ian D. Wilson, Iina Laitinen, Alan Cuthbertson, Juhani Knuuti
Publikováno v:
European journal of nuclear medicine and molecular imaging. 36(12)
Increased expression of αvβ3/αvβ5 integrin is involved in angiogenesis and the inflammatory process in atherosclerotic plaques. The novel 68Ga-DOTA-RGD peptide binds with high affinity to αvβ3/αvβ5 integrin. The aim of this study was to inves