Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Peter I. Schrier"'
1
Transfection of IL-2 Augments CTL Response to Human Melanoma Cells In Vitro
Autor: Suzanne Osanto, Peter I. Schrier, Carolien E. van der Minne, Corlien A. Aarnoudse, Corry W. van der Spek, Nathalie Brouwenstijn, Andrea van Elsas
Publikováno v: Journal of Immunotherapy. 20:343-353
We have transfected human melanoma cell line 518A2 with the cDNA encoding interleukin-2 (IL-2) or granulocyte-macrophage colony-stimulating factor (GM-CSF), and compared cytokine-producing clones for their ability to induce melanoma-specific cytotoxi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e9587d8559f46fab28a4058c3b03e7
https://doi.org/10.1097/00002371-199709000-00003
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2
N-ras oncogene expression changes the growth characteristics of human melanoma in two independent SCID-hu mouse models
Autor: Klaus Wolff, Sue A. Inoue, Burkhard Jansen, Hans-Georg Eichler, Hubert Pehamberger, Andrea van Elsas, Hermine Wadl, Peter I. Schrier
Publikováno v: International Journal of Cancer. 67:821-825
Fifteen percent of all human melanomas carry mutations in ras genes, the majority of which are located in codon 61 of the N-ras gene. However, the biological significance of these mutations is as yet unknown. In this study, we investigated the influe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d00ba272d1b5ab9f892abe7ae580cfb
https://doi.org/10.1002/(sici)1097-0215(19960917)67:6<821::aid-ijc11>3.0.co
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3
Stretch-induced paracrine hypertrophic stimuli increase TGF-beta1 expression in cardiomyocytes
Autor: Annemieke J E T, van Wamel, Cindy, Ruwhof, Lizette J M, van der Valk-Kokshoorn, Peter I, Schrier, Arnoud, van der Laarse
Publikováno v: Molecular and cellular biochemistry. 236(1-2)
Cardiac hypertrophy refers to the abnormal growth of cardiomyocytes, and is often caused by valvular heart disease and hypertension. It involves the activation of growth, including increased protein synthesis and changes in gene expression. Transform
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74e1905df899a3c608fe4b8f2a160fe1
https://pubmed.ncbi.nlm.nih.gov/12190114
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4
TCR reconstitution in Jurkat reporter cells facilitates the identification of novel tumor antigens by cDNA expression cloning
Autor: Corlien A, Aarnoudse, Margreet, Krüse, Renate, Konopitzky, Nathalie, Brouwenstijn, Peter I, Schrier
Publikováno v: International journal of cancer. 99(1)
The identification of novel tumor antigens is of extreme importance for effective immunotherapy against cancer. A major obstacle in this field is the limited life span of tumor-specific cytotoxic T lymphocytes (CTLs) in vitro. Therefore we searched f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9a9aeb4ea73df9c3474cd06deb7fdabd
https://pubmed.ncbi.nlm.nih.gov/11948485
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6
Analysis of N-ras Mutations in Human Cutaneous Melanoma: Tumor Heterogeneity Detected by Polymerase Chain Reaction/Single-Stranded Conformation Polymorphism Analysis
Autor: S. van der Flier, Peter I. Schrier, A. Vacca, M. Kruse-Wolters, S.F. Zerp, A. van Elsas, D. J. Ruiter
Publikováno v: Recent Results in Cancer Research ISBN: 9783642787737
Determination of the activation state of oncogenes as well as tumor suppressor genes is a main subject of interest in the analysis of the mechanism of tumor initiation. In human melanoma, the c-myc and N-ras oncogenes have been found to be activated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bb488275557e7ceb60b06bd7f550426
https://doi.org/10.1007/978-3-642-78771-3_5
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7
Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: growth features and cytogenetics
Autor: Peter I. Schrier, Vincent T.H.B.M. Smit, Anne Hagemeijer, Cees J. Cornelisse, Hedda H. Van Ravenswaay Claasen, Cornelia A. M. van den Berg-Bakker, Peter J. K. Kuppen, Elsa M. Franken-Postma
Publikováno v: International journal of cancer. 53(4)
The characteristics of 7 newly established ovarian carcinoma cell lines and one granulosa tumor cell line obtained from tumor samples of 7 patients with varying histology of the primary tumor are reported. The cell lines were isolated from 5 serous c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c275a4643b2d6ac7a8f46ca3e49e5aaf
https://pubmed.ncbi.nlm.nih.gov/8436435
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8
Melanoma genetics and cytogenetics
Autor: Peter I. Schrier
Publikováno v: Clinics in dermatology. 10(1)
It is now well established that cancer has a genetic basis and is accompanied by structural alterations in the chromosomal DNA. Often, these alterations occur in genes playing an important role in the regulation of proliferation and differentiation.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0753db2c87bc6c6d1ffc410c83477321
https://pubmed.ncbi.nlm.nih.gov/1504926
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9
Role of adenovirus types 5 and 12 early region 1 b tumor antigens in oncogenic transformation
Autor: Johannes L. Bos, René Bernards, Peter I. Schrier, Alex J. van der Eb
Publikováno v: Virology, 127(1), 45. Elsevier
Recently we have reported that the difference in oncogenic potential between adenovirus type 5 (Ad5)- and Ad12-transformed cells in athymic nude mice is specified by early region 1b. In order to determine which of the two early region 1b. (Elb) tumor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8578cd34746e5d7f45d11fdb441b306a
https://dspace.library.uu.nl/handle/1874/13850
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