Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Peter Hollowell"'
Autor:
Peter Hollowell, Zongyi Li, Xuzhi Hu, Sean Ruane, Cavan Kalonia, Christopher F. van der Walle, Jian R. Lu
Publikováno v:
Molecules, Vol 25, Iss 9, p 2047 (2020)
Monoclonal antibodies (mAbs) are an important class of biotherapeutics; as of 2020, dozens are commercialized medicines, over a hundred are in clinical trials, and many more are in preclinical developmental stages. Therapeutic mAbs are sequence modif
Externí odkaz:
https://doaj.org/article/44d1b41bc4d24bfea42125a37085f16b
Autor:
Sean Ruane, Zongyi Li, Peter Hollowell, Arwel Hughes, Jim Warwicker, John R. P. Webster, Christopher F. van der Walle, Cavan Kalonia, Jian R. Lu
Publikováno v:
Molecular Pharmaceutics. 20:1643-1656
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c63e4b09144d941d8e7d1fefdd79a107
https://doi.org/10.1021/acs.molpharmaceut.2c00864
https://doi.org/10.1021/acs.molpharmaceut.2c00864
Autor:
Suman Saurabh, Cavan Kalonia, Zongyi Li, Peter Hollowell, Thomas Waigh, Peixun Li, John Webster, John M. Seddon, Jian R. Lu, Fernando Bresme
Publikováno v:
Molecular Pharmaceutics. 19:3288-3303
Histidine, a widely used buffer in monoclonal antibody (mAb) formulations, is known to reduce antibody aggregation. While experimental studies suggest a nonelectrostatic, nonstructural (relating to secondary structure preservation) origin of the phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cfc736a2bbb02338069722ffd49724
https://doi.org/10.1021/acs.molpharmaceut.2c00453
https://doi.org/10.1021/acs.molpharmaceut.2c00453
Autor:
John R. P. Webster, Frances Separovic, Jack Hart, Luke A. Clifton, Jessica Carter, Andrew J. McBain, Mingrui Liao, Hai Xu, Stephen M. King, Mario Campana, Marc-Antoine Sani, Ke Fa, Thomas A. Waigh, Peter Hollowell, Peixun Li, Haoning Gong, Shiying Zhu, Xuzhi Hu, Jian R. Lu, Armando Maestro
Publikováno v:
Gong, H, Sani, M, Hu, X, Fa, K, Hart, J W, Liao, M, Hollowell, P, Carter, J, Clifton, L A, Campana, M, Li, P, King, S M, Webster, J R P, Maestro, A, Zhu, S, Separovic, F, Waigh, T A, Xu, H, Mcbain, A J & Lu, J R 2020, ' How do Self-Assembling Antimicrobial Lipopeptides Kill Bacteria? ', ACS applied materials & interfaces, vol. 12, no. 50, pp. 55675-55687 . https://doi.org/10.1021/acsami.0c17222
Antimicrobial peptides are promising alternatives to traditional antibiotics. A group of self-assembling lipopeptides was formed by attaching an acyl chain to the N-terminus of α-helix-forming peptides with the sequence Cx-G(IIKK)yI-NH2 (CxGy, x = 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470f1f62fddb3aca4a4af8b3309feb1e
https://doi.org/10.1021/acsami.0c17222
https://doi.org/10.1021/acsami.0c17222
Autor:
Weimiao Wang, Mario Campana, Faheem Padia, Haoning Gong, Huayang Liu, Xuzhi Hu, Gordon Alastair Bell, Peixun Li, Jos Cooper, Jian R. Lu, Mingrui Liao, Peter Hollowell, Elias Pambou, Carlo Bawn, John R. P. Webster, Kun Ma
Publikováno v:
Hu, X, Pambou, E, Gong, H, Liao, M, Liu, H, Hollowell, P & Lu, J R 2020, ' How does substrate hydrophobicity affect the morphological features of reconstituted wax films and their interactions with nonionic surfactant and pesticide? ', Journal of Colloid and Interface Science, vol. 575, pp. 245-253 . https://doi.org/10.1016/j.jcis.2020.04.043
Hypothesis: Surfactants are widely used in agri-sprays to improve pesticide efficiency, but the mechanism underlying their interactions with the surface wax film on plants remains poorly understood. To facilitate physical characterisations, we have r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3c6d8755f0f4505b53cf9490ba92e4
https://doi.org/10.1016/j.jcis.2020.04.043
https://doi.org/10.1016/j.jcis.2020.04.043
Autor:
Daniela Ciumac, Kangcheng Shen, Luke A. Clifton, Andrew J. McBain, Thomas A. Waigh, Jian R. Lu, Haoning Gong, Mingrui Liao, Peter Hollowell, John R. P. Webster, Sorasak Phanphak, Giovanna Fragneto, Mario Campana, Xuzhi Hu, Ke Fa
Publikováno v:
Gong, H, Liao, M, Hu, X, Fa, K, Phanphak, S, Ciumac, D, Hollowell, P, Shen, K, Clifton, L A, Campana, M, Webster, J R P, Fragneto, G, Waigh, T A, Mcbain, A J & Lu, J R 2020, ' Aggregated Amphiphilic Antimicrobial Peptides Embedded in Bacterial Membranes ', ACS applied materials & interfaces, vol. 12, no. 40, pp. 44420-44432 . https://doi.org/10.1021/acsami.0c09931
Molecular dynamics (MD) simulations, stochastic optical reconstruction microscopy (STORM), and neutron reflection (NR) were combined to explore how antimicrobial peptides (AMPs) can be designed to promote the formation of nanoaggregates in bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0454e8b962d267d906cae8154875c6a
https://doi.org/10.1021/acsami.0c09931
https://doi.org/10.1021/acsami.0c09931
Autor:
Sean Ruane, Haoning Gong, Gordon Alastair Bell, Zongyi Li, Huayang Liu, Robert M. Dalgliesh, Jian R. Lu, Elias Pambou, Faheem Padia, Mingrui Liao, Najet Mahmoudi, Peter Hollowell, Xuzhi Hu
Publikováno v:
Journal of colloid and interface science. 586
Hypothesis Surfactants have been widely used as adjuvants in agri-sprays to enhance the solubility of pesticides in foliar spray deposits and their mobility through leaf cuticles. Previously, we have characterised pesticide solubilisation in nonionic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf46c636e6731f0ba56a745b8c60f7a9
https://pubmed.ncbi.nlm.nih.gov/33162043
https://pubmed.ncbi.nlm.nih.gov/33162043
Autor:
Sean Ruane, Faheem Padia, Elias Pambou, Gordon Alastair Bell, Huayang Liu, Carlo Bawn, Sarah E. Rogers, Kun Ma, Peter Hollowell, Stephen M. King, Peixun Li, Jian R. Lu, Xuzhi Hu, Zongyi Li, Haoning Gong
Publikováno v:
Journal of colloid and interface science. 556
Hypothesis Nonionic surfactants are used as adjuvants in agri-sprays to stabilise pesticides, but what happens when pesticide-loaded micelles are brought into direct contact with plant leaves? As pesticide solubilisation dehydrates the micellar shell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0de311e92b5e6761c3140f348da9d5e
https://pubmed.ncbi.nlm.nih.gov/31499436
https://pubmed.ncbi.nlm.nih.gov/31499436