Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Peter Henklein"'
Autor:
Michael Henkel, David Mitzner, Peter Henklein, Franz-Josef Meyer-Almes, Anna Moroni, Mattia L Difrancesco, Leonhard M Henkes, Michael Kreim, Stefan M Kast, Ulrich Schubert, Gerhard Thiel
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11112 (2010)
BackgroundPB1-F2 is a proapoptotic influenza A virus protein of approximately 90 amino acids in length that is located in the nucleus, cytosol and in the mitochondria membrane of infected cells. Previous studies indicated that the molecule destabiliz
Externí odkaz:
https://doaj.org/article/d750ef13fc514eb9ab39d492520fe55b
Autor:
Sara Pagans, Angelika Pedal, Brian J North, Katrin Kaehlcke, Brett L Marshall, Alexander Dorr, Claudia Hetzer-Egger, Peter Henklein, Roy Frye, Michael W McBurney, Henning Hruby, Manfred Jung, Eric Verdin, Melanie Ott
Publikováno v:
PLoS Biology, Vol 3, Iss 2, p e41 (2005)
The human immunodeficiency virus (HIV) Tat protein is acetylated by the transcriptional coactivator p300, a necessary step in Tat-mediated transactivation. We report here that Tat is deacetylated by human sirtuin 1 (SIRT1), a nicotinamide adenine din
Externí odkaz:
https://doaj.org/article/1f4e87794ef5457ca7e901e53e2cc8de
Autor:
Ilse Drung, Peter Henklein, Ulrike Kuckelkorn, Peter M. Kloetzel, Karin Klingel, Karl Stangl, Christin Keller, Antje Voigt, Kathrin Textoris-Taube, Sandra Jäkel, Gudrun Szalay
Publikováno v:
Amino Acids. 39:243-255
Proteasomes are known to be the main suppliers of MHC class I (MHC-I) ligands. In an attempt to identify coxsackievirus B3 (CVB3)-MHC-I epitopes, a combined approach of in silico MHC-I/transporters associated with antigen processing (TAP)-binding and
Autor:
René Röder, Hardy Weißhoff, Clemens Mügge, Ulrich S. Schubert, Louis A. Carpino, Peter Henklein, Petra Henklein, Michael Pätzel
Publikováno v:
Journal of Peptide Science. 16:65-70
To prevent aspartimide formation and related side products in Asp-Xaa, particularly Asp-Gly-containing peptides, usually the 2-hydroxy-4-methoxybenzyl (Hmb) backbone amide protection is applied for peptide synthesis according to the Fmoc-protocols. I
Publikováno v:
Zeitschrift für Naturforschung B. 64:1159-1168
Two types of lanthanide complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) for the labelling of biomolecules were investigated by HPLC, MS and NMR spectroscopy. The elution behavior of lanthanide complexes of N-functionalize
Autor:
Eberhard Krause, Adel Ali Abdel-Maksoud, Holger Wenschuh, Ayman El-Faham, Michael Beyermann, Michael Bienert, Peter Henklein, Louis A. Carpino, Dumitru Ionescu, Khaled Nasr
Publikováno v:
Organic letters, 11(16): 3718–3721
The N-dicyclopropylmethyl (Dcpm) residue, introduced into amino acids via reaction of dicyclopropylmethanimine hydrochloride with an amino acid ester followed by sodium cyanoborohydride or triacetoxyborohydride reduction, can be used as an amide bond
Autor:
Paul W. Sheppard, Marion Schmolke, Alexander Kloss, Dagmar Siele, Peter Henklein, Burkhardt Dahlmann, Sébastien Apcher, Lothar Kuehn
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 72:219-225
Oligo-arginines are cell-penetrating peptides and find use as carriers for transportation of various membrane-impermeable biopharmaceuticals into target cells. We have found that oligo-arginines of a length of 4-10 amino acids, but especially (Arg)(8
Autor:
Josef FLOßDORF, Victor Wray, Torsten Federau, Ulrich Schubert, Peter Henklein, Dietmar Schomburg
Publikováno v:
International Journal of Peptide and Protein Research. 47:297-310
The HIV-1-specific Vpu protein is an 81 amino acid class I integral membrane phosphoprotein that induces degradation of the virus receptor CD4 in the endoplasmic reticulum and enhances the release of virus particles from infected cells. Vpu is of amp
Autor:
Jason Kindrachuk, Sandy Hsiang Yu Chiang, Rudolf Volkmer, Lindsay L. Weaver, Melissa Elliott, Nelly Panté, Dirk F. H. Winkler, Susan W. Farmer, Kai Hilpert, Jana Körner, Håvard Jenssen, Anne S. Ulrich, Robert E. W. Hancock, Peter Henklein, Christopher D. Fjell
Publikováno v:
Chemistry & Biology; Vol 16
SummaryThere is an urgent need to coat the surfaces of medical devices, including implants, with antimicrobial agents to reduce the risk of infection. A peptide array technology was modified to permit the screening of short peptides for antimicrobial
Autor:
Takeshi Watanabe, Christa Scholz, Helga Wessner, Peter Henklein, Gerd Hansen, Cordula Petter, Wolfgang Höhne
Publikováno v:
Journal of Molecular Recognition. 21:401-409
A phage display library with disulfide-cyclized peptides was screened for peptides binding to chitinases from Serratia marcescens. One of those peptides was found to efficiently inhibit chitinase A and two others were inhibitors of chitinase B. Compl